Gene Information

Name : pykF (Pro0923)
Accession : NP_875315.1
Strain : Prochlorococcus marinus CCMP1375
Genome accession: NC_005042
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 839129 - 840913 bp
Length : 1785 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGACAACGATAGATCTAAAACGTAGGACAAAGATCGTTGCGACAATAGGCCCTGCAACAGAAAGTCCAGAGAAAATCAC
AGAGCTTATTAAAGCAGGTGCTACAACCTTTAGACTGAATTTCTCGCATGGAGATCATGAAGAACATGCAAAACGGATAA
AAACCATCAGATCTGTTGCATCAGATTTAGGAGTAAACATAGGCATTCTTCAGGATTTACAAGGTCCTAAAATCAGATTA
GGAAGATTTAAAGAGGGTCCAGTCAACCTAAAAACAGGAGATGTATTTGCCCTAACTTCAGAAAACAAAGACTGCAATCA
GGAAATAGCTAATGTCACCTATGAAAACCTTGTCAATGAGGTGGAAAAAGGAAAAAGAATATTATTAGATGATGGAAGAG
TCGAAATGATTGTAGAGAATGTAGACAAGAAAAACAAATCACTTATTTGCAAAGTCACAGTTGGTGGAATTCTTTCAAAC
AACAAAGGGGTTAATTTCCCTGACGTACAACTATCAATTAATGCTTTAACTGAAAAAGATAAAATAGACCTTTCATTTGG
TCTAAAACAAGGAGTTGACTGGGTAGCTCTAAGTTTTGTTAGGAATCCAGCGGATATTCAAGAAATCAAGGAATTAATCA
GACGGCATGGTTATACCACTCCAATAGTTGCAAAAATAGAGAAATTTGAAGCAATAGACCAAATAGATTCAATACTCAGC
CTTTGTGATGGGGTGATGGTTGCAAGAGGCGATTTGGGTGTTGAAATGGATGCAGAAGAAGTACCTTTGCTGCAGAAAGA
ATTAATTAAAAAGGCCAATAGCCTTGGGATACCAATTATTACAGCTACCCAGATGTTGGATTCGATGGCCTCGAGTCCTA
GACCAACTAGGGCAGAAGTTAGCGATGTAGCTAATGCAATACTTGATGGTACAGATGCAGTAATGCTTTCTAACGAAACA
GCAGTGGGAGATTATCCAATAGAAGCTGTCGAAACCATGGCAAAAATAGCAAGAAGAATCGAGAGGGATTACCCACAAAG
AGCTTTAGAAAGCCACCTTCCAAGTACAATTCCTAATGCAATTAGTGCCGCAGTAAGTACTATTGCAAGACAATTAAACG
CAGCAGCAATACTTCCCCTAACTAAAAGTGGTGCAACTGCTCATAATGTGAGTAAGTTTCGTCCTGCTACCCCAATTCTT
GCCATAACAAGTGAAATTAGCGTCGCAAGAAGACTTCAATTGGTATGGGGTGTATCTCCCTTGTTGATAGATGCTCAAAA
AAGCACAAGCAAAACCTTTGGAATAGCAATGGAGCAGGCAATGGACATGAAATTATTAAAGCCCGGAGATCAAGTAGTAG
AAACAGCAGGAACCCTAACAGGCATAAGTGGTTCAACAGATTTAATTAAAGTAGGAATTGTCAGCAAGATAGTAGCGAGC
GGAAAAACAAAACCAATCGTTAAAGAAGGAACAATAAGTGGCAAACTTAGAGTTATAAATAAAGCAACCGATCTGTCAGA
TTTAAAATCAGGCGAAATACTAGTACTTGCAGAAAATGTACAATATAATTTGGACACTAAAACTCATATATCAGCAATGA
TATTTGAAGGCGAATATTCATTAATCAATACAAATAATCAAATTGAAGATAATAATATAATTCCTGCTATATATAATGTA
GAAGGAGCATGTACTAAATTTAAAAATGGCGAGATTGTCACACTAGATCTTAAAGATGGAAATATAATAAAGGGTCTTGC
TCAGGACCTGAAAACATATAATTAA

Protein sequence :
MTTIDLKRRTKIVATIGPATESPEKITELIKAGATTFRLNFSHGDHEEHAKRIKTIRSVASDLGVNIGILQDLQGPKIRL
GRFKEGPVNLKTGDVFALTSENKDCNQEIANVTYENLVNEVEKGKRILLDDGRVEMIVENVDKKNKSLICKVTVGGILSN
NKGVNFPDVQLSINALTEKDKIDLSFGLKQGVDWVALSFVRNPADIQEIKELIRRHGYTTPIVAKIEKFEAIDQIDSILS
LCDGVMVARGDLGVEMDAEEVPLLQKELIKKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDYPIEAVETMAKIARRIERDYPQRALESHLPSTIPNAISAAVSTIARQLNAAAILPLTKSGATAHNVSKFRPATPIL
AITSEISVARRLQLVWGVSPLLIDAQKSTSKTFGIAMEQAMDMKLLKPGDQVVETAGTLTGISGSTDLIKVGIVSKIVAS
GKTKPIVKEGTISGKLRVINKATDLSDLKSGEILVLAENVQYNLDTKTHISAMIFEGEYSLINTNNQIEDNNIIPAIYNV
EGACTKFKNGEIVTLDLKDGNIIKGLAQDLKTYN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-79 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-79 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-79 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-79 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF NP_875315.1 pyruvate kinase VFG0479 Protein 9e-80 45