Gene Information

Name : hemC (Pro0494)
Accession : NP_874887.1
Strain : Prochlorococcus marinus CCMP1375
Genome accession: NC_005042
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 470762 - 471709 bp
Length : 948 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGCTCTAGACCAAGTGCGTATTGCTTCACGACGCAGCCAACTAGCCATGGTTCAGACAAACTGGGTAAAGGAAGAGCT
TGAAAAAGCCTGCCCCAGCATTGACATTTCCATAGAAGCGATGGCAACTCAAGGAGACAAAATTCTTGATGTAGCACTTG
CCAAAATTGGAGACAAAGGTCTTTTCACCAAAGAGCTTGAGGCTCAAATGCTGATTGGTCGTGCAGATATCGCAGTTCAT
TCTTTAAAAGATCTTCCAACCAACCTTCCTGAAGGGTTAATGCTTGGGTGCATAACTAAAAGGGAAGATCCTGCAGATGC
TCTAGTTGTAAATAAAAAATATAAGAATTACCAACTCAACGATCTTCCTGAAGGATCCGTTGTTGGGACAAGTTCTTTAA
GACGCTTAGCACAACTCCGACACCATTATCCAGGCCTTATTTTCAAAGATGTCCGTGGAAATGTAATTACACGCTTAGAG
AAGCTAGATTCAGGCGAATACGATTGTTTAATTTTGGCAGCTGCAGGGTTAACAAGACTTGGTTTTGGTAACAGAATTCA
TCAACTAATTCCTAGTGAAATATCACTTCATGCCGTAGGGCAAGGAGCTTTAGGAATAGAGTGCGTAAAAGACAAAGAAG
AAATACTCCAAATCATAAAAGTTCTAGAACATAAAGAATCTTCTTTAAGATGCCTTGCAGAGAGAGCATTTCTAAAGGAA
CTAGAAGGGGGGTGTCAAGTCCCTATTGGAGTCAACAGTAAAATTCAGGGACAAGAGCTCATCCTTACTGGCATGGTTGC
AAGCCTTGATGGTAAACAGCTAATAAGAGATACAAAAACAGGTTCTAGTATGCACCCGGAAACAATAGGGATAGAGCTAG
CAAATACTCTTAAATCGCAAGGAGCAATGGAAATACTAGAAGTGATTTTCAAAGAAGCACGAGCGTGA

Protein sequence :
MALDQVRIASRRSQLAMVQTNWVKEELEKACPSIDISIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLIGRADIAVH
SLKDLPTNLPEGLMLGCITKREDPADALVVNKKYKNYQLNDLPEGSVVGTSSLRRLAQLRHHYPGLIFKDVRGNVITRLE
KLDSGEYDCLILAAAGLTRLGFGNRIHQLIPSEISLHAVGQGALGIECVKDKEEILQIIKVLEHKESSLRCLAERAFLKE
LEGGCQVPIGVNSKIQGQELILTGMVASLDGKQLIRDTKTGSSMHPETIGIELANTLKSQGAMEILEVIFKEARA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-60 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-60 49