Gene Information

Name : tktA (Pro1770)
Accession : NP_876161.1
Strain : Prochlorococcus marinus CCMP1375
Genome accession: NC_005042
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1624148 - 1626157 bp
Length : 2010 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCGCCTGTTTCTCTTGAATCGCTCTGCATTAACAGCATAAGAATGCTCGCTGTAGATGCAGTAAATAAATC
CAAAAGTGGGCATCCTGGCCTGCCTATGGGATGTGCACCTATGGGGTATACCCTATGGGACAAATTTCTCAGACATAATC
CTAAAAATCCTAAGTGGTTCAATCGAGACCGTTTTGTTCTTTCTGCAGGTCATGGGTGCATGCTTTTATATGCACTGTTG
CATTTAACTGGCTATGACTCAGTCACGATCGATGATATAAAACAATTTCGTCAATGGGGTGCAAGAACTCCTGGTCACCC
TGAAACATTTGAAACTGCTGGTGTAGAAGTAACCGCGGGGCCATTGGGAGCAGGCATATCAAACGCAGTAGGCCTTGCAA
TAGCAGAAGCCCATCTTGCTGCCAAATTCAATAAAGCAGATGCCAAAATCGTTGATCACTTCACATACGTGATAATGGGA
GATGGATGCAATCAAGAGGGAGTTGCATCAGAAGCTTGCTCTCTTGCAGGCCATCTCAAGTTAGGTAAATTAATTGCGTT
ATATGACGACAATCACATAACAATTGATGGTCGAACTGATGTTTCATTCACAGAGGATGTACTAAAACGCTATGAATCCT
ATGGATGGCATGTTCAACATGTTCAAGAAGGTAATACTGATGTAGATGCAATTGCCAAAGCAATTGAGTCAGCAAAAGCA
ATTTCTGACAAACCATCCATTATCAAAGTTACAACAACAATTGGTTTTGGATCTCCTAACAAAAGTGATACCGCAGGAGT
TCATGGTGCGCCTCTAGGCGAGGAAGAGGCTGAACTGACTAGGAAATCATTGGATTGGCCATATGAACCCTTTGAAATTC
CTAATGAGGTTTATCAGCAATATCAAAAAGCAATAGTGCGTGGCGAGAGCTTAGAAAAAGAATGGAATCAATTGTTAGAT
AATTATCGAAAAAAATATTCTAATGAAGCTGAAGAATTCGAAAGAATGTTAAGAGGTGAACTCCCTTCAGACTGGGATAA
AGACTTACCTTCATACACCCCTAAAGACAATGGACTAGCAACTCGAAAACATTCTCAAATATGTCTAGGTGCAATTGGTC
CCAATCTTCCTGAACTAATTGGTGGTTCTGCTGATTTAACTCACTCAAATTACACAGACATCAAGGGTGAAAGTGGTTCT
TTCCAGCCTGAAACACCTGAGAAACGTTACCTTCACTTTGGTGTCAGAGAACATGCGATGGCAGCAATACTGAATGGAAT
TGCTTATCACAACAGTGGATTAATACCCTATGGAGGAACTTTCCTCGTTTTCGCTGATTACATGAGAGGGTCGATGCGAT
TATCTGCTCTCAGTGAACTTGGCGTTATCTACGTATTGACTCATGACTCCATTGGTGTTGGAGAGGATGGTCCTACTCAT
CAACCCATTGAAACTATTCCTTCTCTACGAGCAATACCAAATATGCTTGTTTTTAGACCAGGAGATGGCAATGAAACTTC
TGGAAGCTATAAACTTGCAATAGAAAATCGCAAACGTCCTAGTTCTCTTTGTCTCAGCAGACAAGGCATGCCTAATCAAG
CAAATTCATCAAGTAAAAAAGTTGCATTAGGAGGATACGTTATTGAGGATTGTGTAGGCACACCAGATCTCATTTTGATT
GGTACAGGTTCCGAATTAAATCTATGTATTGAAGCTGCTCAAGAGCTAACAAATCAAGGTAAAAAAATTAGAGTTGTTTC
AATGCCTTGTATGGAACTTTTTGAAGAGCAAAGCGCATCATACAAAGAAGAGGTTTTACCTCCTCTTGTTAGAAAAAGGT
TAGTTGTAGAAGCTGCACTGTCATTCGGATGGCATAAATATATAGGCCTTGATGGAGACAGCGTTACTATGAATAGTTTC
GGCGCATCTGCACCCGGAGGAACATGTATGGAAAAATTTGGGTTTACAGTTGAAAATGTTATCAATAAAGCAAAGAAACT
TCTTAACTAA

Protein sequence :
MVAAPVSLESLCINSIRMLAVDAVNKSKSGHPGLPMGCAPMGYTLWDKFLRHNPKNPKWFNRDRFVLSAGHGCMLLYALL
HLTGYDSVTIDDIKQFRQWGARTPGHPETFETAGVEVTAGPLGAGISNAVGLAIAEAHLAAKFNKADAKIVDHFTYVIMG
DGCNQEGVASEACSLAGHLKLGKLIALYDDNHITIDGRTDVSFTEDVLKRYESYGWHVQHVQEGNTDVDAIAKAIESAKA
ISDKPSIIKVTTTIGFGSPNKSDTAGVHGAPLGEEEAELTRKSLDWPYEPFEIPNEVYQQYQKAIVRGESLEKEWNQLLD
NYRKKYSNEAEEFERMLRGELPSDWDKDLPSYTPKDNGLATRKHSQICLGAIGPNLPELIGGSADLTHSNYTDIKGESGS
FQPETPEKRYLHFGVREHAMAAILNGIAYHNSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPIETIPSLRAIPNMLVFRPGDGNETSGSYKLAIENRKRPSSLCLSRQGMPNQANSSSKKVALGGYVIEDCVGTPDLILI
GTGSELNLCIEAAQELTNQGKKIRVVSMPCMELFEEQSASYKEEVLPPLVRKRLVVEAALSFGWHKYIGLDGDSVTMNSF
GASAPGGTCMEKFGFTVENVINKAKKLLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-156 51
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-152 50