Gene Information

Name : serS (Pro1304)
Accession : NP_875695.1
Strain : Prochlorococcus marinus CCMP1375
Genome accession: NC_005042
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1203372 - 1204649 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCTTGATCAGAGAAAGATTAGAGAAAACCCAACTCTTATAGAAAAAGGCTTAGCTCGTCGTGGCTTAAAAGTTAATTT
GGCCCCTTTAACAGAAGCTAGTGAAAGACTTAAAGGACTGGAGCAGCATCGCAATTCTTTACAAGCAAAAGGGAATTTAA
TAGGTAAAGAAGTTGGCCAGAAAATTAAATCTGGCATTAGTCCTAATTCAGAAGAAGTTGTTTCATTACGCAGCAAAGGC
AATGAATTGAAAAGAGAAATAAATGTACTTGAAGAAGAAGAAAAAGCTCTAGCCAAGTCAATTAGAAAAAGAATTCTCAA
TTATCCAAATATCCCTTATTCAGAATGTCCTGATGGGAAGGATGAAAATGACAACCTTCAAATACGTAATTGGGGGAATC
CTCTAAAAGGTGAAGGATATAAAGAACATTGGGAAATAGCTGAAGAGCTTGGTCTACTTGATACAGAAAAATCAGTTCGA
ATTGCAAAAAGCCGCTTTGTAACTCTTTTCAACCATGGAGCAAGGTTAGAAAGATCACTAATTAACTTTATGCTGGATAT
TCATACTTCTAAGGGATATTCAGAAGTACTTCCTCCTGTTCTTGTTAACACAGCAAGTCTTGAAGGCTCTGGACAACTTC
CAAAATTTGCAGAAGAAAGCTTTAAATGTTCAGAAGATGATCTTTGGCTGACTCCAACAGCAGAAGTACCTTTAACTTCT
TTACATAGAAATGAAGTTATACCTTTTGAAAAACTACCAATTAAATATGTAGCGTATAGCCCTTGTTTTCGAAGAGAAGC
TGGAAGCTATGGTCGAGATACTAGAGGTCTAATAAGACTACATCAGTTCAATAAAGTTGAACTTTATTGGTTCGTTGAGC
CTAAAAAATCTAAAGAAGCACACCAAATCATTACTGCAGACGCAGAAGCCATTCTTCAGAAACTAGAATTACCCTATAGA
GTTGTAGAGCTTTGTTCAGGAGATTTAGGATTCTCAGCTTCATGCACATATGACTTAGAAGTTTGGCTCCCTGGAGCAAA
TTCCTACAGAGAGATTTCTAGTTGCAGCAATTGTGATGATTTTCAAGCCAGGCGATCTTTTATTAGGACTAAGAAAGGCA
ATCAAACTCAACTTGTTCATACTCTCAACGCTAGCGGTTTAGCAATTGGCAGAACAATGGCAGCAATACTAGAGAATGGA
CAGCAATCTGATGGAACTGTCAAACTGCCAAAAGCACTAGTCCCATATTTTGGAGAGAACCAATTGACCCCTCAATAA

Protein sequence :
MLDQRKIRENPTLIEKGLARRGLKVNLAPLTEASERLKGLEQHRNSLQAKGNLIGKEVGQKIKSGISPNSEEVVSLRSKG
NELKREINVLEEEEKALAKSIRKRILNYPNIPYSECPDGKDENDNLQIRNWGNPLKGEGYKEHWEIAEELGLLDTEKSVR
IAKSRFVTLFNHGARLERSLINFMLDIHTSKGYSEVLPPVLVNTASLEGSGQLPKFAEESFKCSEDDLWLTPTAEVPLTS
LHRNEVIPFEKLPIKYVAYSPCFRREAGSYGRDTRGLIRLHQFNKVELYWFVEPKKSKEAHQIITADAEAILQKLELPYR
VVELCSGDLGFSASCTYDLEVWLPGANSYREISSCSNCDDFQARRSFIRTKKGNQTQLVHTLNASGLAIGRTMAAILENG
QQSDGTVKLPKALVPYFGENQLTPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-82 46