Gene Information

Name : kpsU (RB12690)
Accession : NP_870651.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 6833336 - 6834088 bp
Length : 753 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAGTGCATGATCGTCATTCCCGCTCGCTTGGCCTCCTCTCGCCTCAGTCAAAAACTGTTGCTGCAAGCGGGCGGCAA
ATCAGTTCTGCAGCACACCTACGAAGCCGCCCTGAAATCGTCCGTCGCAGAGGAAGTGATCGTTGCGGTCGATGACCCGA
GACTTGCGGCTGAAGTCGATTCGTTCGGCGGGCAGGCTCGGTTGACCAGCGTTGACTGTCAAAGCGGAACCGATCGAATC
GCGGAAGTCGCTCTGATGCACGAAGACATCAACATCTTAATCAATGTCCAAGGCGACGAACCCGAAATCGATCCCAAGAC
GATCGATGCGGTGGCAAAGCTTTTGATGCAGCATCCCGAAGCTGACATTGCCACCGCGGCTTGTGCCATCAAAGATCGAG
AGCGAGTGGAAGACCCAAACTGTGTCAAAGCCGTCTTAGGCGACGACCACCGCGCGATCACCTTCAGTCGCGCTGCCGTT
CCGCATCCCCGCGATGGATTAACGGACGCCTTGCTCAATGCGGAACCGCCCAACTACTGGCAGCACATCGGGCTGTATGC
CTATCGTCGCGAATTCCTACTTTGGTTCGCGACTCAACCGCCCGGTCGTCTGGAGCAAATTGAAAAACTCGAACAACTCC
GAGCCATCGAAGCAGGAAAAACGATTGTTGTCGCCCCCGTCGAAGCATCCGCTCCGGGAATCGACACGCTCGAAGACTTC
CGTGCCTTCACAGCGAGAATCGAGTCTCAGTGA

Protein sequence :
MKCMIVIPARLASSRLSQKLLLQAGGKSVLQHTYEAALKSSVAEEVIVAVDDPRLAAEVDSFGGQARLTSVDCQSGTDRI
AEVALMHEDINILINVQGDEPEIDPKTIDAVAKLLMQHPEADIATAACAIKDRERVEDPNCVKAVLGDDHRAITFSRAAV
PHPRDGLTDALLNAEPPNYWQHIGLYAYRREFLLWFATQPPGRLEQIEKLEQLRAIEAGKTIVVAPVEASAPGIDTLEDF
RAFTARIESQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-36 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 7e-37 43
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-36 43