Gene Information

Name : thyA (RB12614)
Accession : NP_870607.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 6794945 - 6795739 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAAGGCTATTTGCAACTATTAGACGAAGTCCTGCATGACGGGATTGATCGAGACGACCGGACGGGCGTCGGCACTCG
CAGTCTGTTTGGACGCCAAATGCGGTTTGATTTGGCGGAGGGTTTTCCTCTGTTGACGACTAAGAAGCTGCATATCCGGT
CGATTTTGCACGAATTGCTGTGGTTCCTTCGCGGGGACACCAACATCGGTTACCTAAAAGAGAACAAGGTTTCGATTTGG
GACGAGTGGGCCGATGAGGCCGGCGATCTGGGCCCGGTCTACGGTCACCAATGGCGAAGCTGGGAAGGTGCCAACGGCGA
CACGGTCGACCAAATCGCTTGGGTCGAAAACGAAATTCGCACCAACCCGAGATCACGCCGTTTGGTCGTTTCGGCTTGGA
ACGTGGCCGATGTGCCGAAGATGGCTTTGCCGCCGTGTCATTTGCTGTTTCAGTTTTATGTTTCTGGCGGACGGCTGTCT
TGTCAGTTGTATCAACGCAGCGCGGATTTGTTTTTGGGAGTGCCGTTCAATATCGCCAGCTACGCGATGTTGACGTCGAT
GATGGCCCATGTCACGGGTCTGAAGCCGGGCGAATTTGTTCACACGCTTGGCGACGTTCATCTCTATAGCAACCACTTCG
ACCAAGCTCGCGAACAACTCAGCCGAACGCCTCGGCCGTTGCCGACGTTTCATATCAAGCGAGACGTCGCATCGGTCACG
GATTTCCAGTTCGATGATTTCGAGCTGACAAACTACGACCCCCATCCCCACATCAAGGCTCCGGTGGCAGTTTAA

Protein sequence :
MQGYLQLLDEVLHDGIDRDDRTGVGTRSLFGRQMRFDLAEGFPLLTTKKLHIRSILHELLWFLRGDTNIGYLKENKVSIW
DEWADEAGDLGPVYGHQWRSWEGANGDTVDQIAWVENEIRTNPRSRRLVVSAWNVADVPKMALPPCHLLFQFYVSGGRLS
CQLYQRSADLFLGVPFNIASYAMLTSMMAHVTGLKPGEFVHTLGDVHLYSNHFDQAREQLSRTPRPLPTFHIKRDVASVT
DFQFDDFELTNYDPHPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-74 58