Gene Information

Name : RB10172 (RB10172)
Accession : NP_869285.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 5498330 - 5499799 bp
Length : 1470 bp
Strand : -
Note : PMID: 9369242 best DB hits: BLAST: gb:AAA64636.1; (U07235) aldehyde dehydrogenase [Mus musculus]; E=1e-163 gb:AAA51693.1; (M20456) aldehyde dehydrogenase [Homo sapiens]; E=1e-163 pir:DEHUE2; aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) 2 precursor,; E=1e-16

DNA sequence :
ATGTCGACAACCCTTCCAGAAATCGCACCCCCAAAAGTCCGTCACACCCAGTTGTTCATCGACGGCCAATGGCGGGATTC
AGCCAGCGGAAAAACGTTCGCCACGATCAACCCGGCCACCGAAGAAGAGATCGTTCAAGTCGCCGAAGGTGACAAGGAAG
ACATCGACGCTGCAGTGAAAGCGGCTCGCAAAGCGTTTGAGTCGGGTCCCTGGCGGACGATGGACGCTCGCGATCGCGGA
CGGCTGATGATGAAGTTGGCCGATGCGATCGAGAACGAGATCGATGAGCTGGCTCAACTCGAAACACTCGACAACGGGAA
ACCCCTTCGCGAATCGCGACATGCGGATTTGCCCTTGGTGATCGATGCCCTCCGCTACTACGCCGGCTACGCGGACAAGA
TCCAAGGCGAAACGGTTCCCATTCGTGGGAACTACCTCTGCTACACACGGAAAGAACCGGTCGGTGTGGTTGGACAGATC
ATCCCTTGGAACTTCCCCATGTTGATGGTCGCTTGGAAGTGGGGACCGGCTCTCGCCACTGGCTGCACGATCGTGATGAA
ACCCGCTGAACAGACACCGCTGACCTGCTTGCGGATGGCGCAGCTCGCCAAAGAGGTTGGCTTCCCCGATGGCGTCATCA
ATGTCGTGCCGGGCTTTGGCCCGACCGCCGGTGGAGCCCTGGTCGACCATCCTGGCGTCGACAAAATCGCCTTCACGGGA
GAACACCGAACGGCTCAATTGATTATGAAGAACTCCGCCCAATCGTTGAAACGACTGACGTTTGAACTGGGCGGCAAAAG
TCCCAATGTGATCTTCAGCGACGCGGACTTGGATGCCGCCGTGCAAGGCAGCTTCGTGGGTCTGTATCTGAACCAAGGCC
AATGTTGCTGTGCCGGCAGTCGCGTGTTCGTCGAAGAATCGATTCACGAAGCCTTCGTCGAAAAACTGACCGATTTGACA
AACAAACGTGTCGTCGGCAACCCATTTGAACACACCACCGAACAGGGTCCTCAAATCGACCAAGCTCAATTCGACAAGAT
CATGAGCTACATCGACAAAGGCAACCAGCAAGGCGCGTCCTGCGTCAGTGGTGGCAAGCGTTCCGGAGATCGTGGTTACT
TCATTGAGCCGACCGTGTTCACTGACGTTCAAGACGACATGGCGATCGCTCGCGATGAAATCTTCGGTCCTGTGATGAGC
GTGCTGTCATTCAAAGACAGCGACGACATTCTGAAACGAGCCAACGACACGATGTTTGGATTAGCGGCCGCCGTGTGGAC
GCAAGACATCAAGAAAGCTCACCACTTCGCCGCCAACGTTCGCGCGGGAACCGTGTGGGTCAACTGTTACGACGTCTTCG
ACGCCGCCGCCCCATTCGGCGGATTCAAGATGAGTGGCCAAGGCCGCGAACTAGGCACCGAAGGCCTGAAGGCTTACCTG
GAAAGCAAAACCGTGACGGTGGCCCTTTGA

Protein sequence :
MSTTLPEIAPPKVRHTQLFIDGQWRDSASGKTFATINPATEEEIVQVAEGDKEDIDAAVKAARKAFESGPWRTMDARDRG
RLMMKLADAIENEIDELAQLETLDNGKPLRESRHADLPLVIDALRYYAGYADKIQGETVPIRGNYLCYTRKEPVGVVGQI
IPWNFPMLMVAWKWGPALATGCTIVMKPAEQTPLTCLRMAQLAKEVGFPDGVINVVPGFGPTAGGALVDHPGVDKIAFTG
EHRTAQLIMKNSAQSLKRLTFELGGKSPNVIFSDADLDAAVQGSFVGLYLNQGQCCCAGSRVFVEESIHEAFVEKLTDLT
NKRVVGNPFEHTTEQGPQIDQAQFDKIMSYIDKGNQQGASCVSGGKRSGDRGYFIEPTVFTDVQDDMAIARDEIFGPVMS
VLSFKDSDDILKRANDTMFGLAAAVWTQDIKKAHHFAANVRAGTVWVNCYDVFDAAAPFGGFKMSGQGRELGTEGLKAYL
ESKTVTVAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-91 44
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-84 44
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 5e-62 43
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 9e-95 43
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 9e-95 43
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 9e-95 43
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-94 43
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 3e-62 42
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 3e-62 42
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 3e-62 42
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 2e-62 42
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 2e-62 42
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 7e-62 42
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 7e-62 42
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 2e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RB10172 NP_869285.1 aldehyde dehydrogenase VFG0082 Protein 1e-91 44