Gene Information

Name : arsA (RB9551)
Accession : NP_868947.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Resistance
Product : ArsA-catalytic subunit of arsenic oxyanion-translocating ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 5135358 - 5137139 bp
Length : 1782 bp
Strand : -
Note : PMID: 9464374 best DB hits: BLAST: gb:AAD51849.1; AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4]; E=1e-162 swissprot:O50593; ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE; E=1e-148 swissprot:P52145; ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE; E=1e-147 COG: M

DNA sequence :
ATGCACTATCTCGAATCACCCACTCGCAATTTGTTCTTCACGGGCAAAGGAGGCGTTGGCAAAACGTCCATGGCTTGTGC
CACCGCGGTTCGTTTGGCGGATCGAGGCCGGCGCGTTCTGCTCGTGTCGACCGACCCCGCGTCAAACTTGGACGAAGTCC
TCGGCGTGACGCTCAGTAACAAGCCGACATCCGTTCCGGCGGTGGACAACCTTTCGGCGATGAACATTGATCCGGAGCAG
GCGGCGGCGGAGTATCGCGAGCGAATGGTGGGGCCGTATCGAGATGTTTTGCCCGAGGCTGCTGTTCAGAGCATGGAAGA
ACAGTTCTCGGGATCGTGCACGGTGGAGATCGCTGCTTTCGACGAATTCGCCAGACTGTTGGGCGACGAAAACGCGACGG
CAGACTTTGATCACATCGTTTTTGACACCGCGCCGACCGGACACACGTTGCGGTTGTTGACGTTGCCATCAGCTTGGTCG
GGATTCATGGATGAAAACACGTCCGGAACATCGTGTCTGGGACCGCTGGCAGGTTTGCAAAAGCAGCAAGCGATCTACCA
TTCGACGGTGGAGTCCCTTGGCGATTCATCTCGCACAACGTTGGTGTTGGTGACTCGACCGGAAGCGTCCACGCTTCGGG
AGGCTGATCGAACCAGCGACGAACTGAGGGAGCTCGGCGTTGAAAACCAAGCCTTGGTGATCAACGGAACCTTCGAGGCA
AGAGACAAATCAGATCCGATTGCCAACGCGATGGAACAACGGTGCAAAGAAGCGTTGATGGCGATGCCCAGCGGGCTCGC
TCAACTGCAACGCACGGTTGTGCCTTTGGCACCTCATGGCTTGGTTGGTATTGACGCTCTACGTCTGCTCGGGAGAACTG
AACCGAACGGGGAGATGGCCAGGAACGAGATTGCCGGTGAAGAACGCGTTTCGATCTTGGAGGCATTGCCCGCATCCGCT
TTGATCGATCAGTTGGCGACTCAGCAACACGGCGTGATTCTGACGATGGGCAAAGGTGGCGTCGGTAAAACAACCATCGC
TGCTGCGGTTGCGGTGGCACTTGCCGAACGCGGCTTGAAGGTTCATTTGTCGACCACCGATCCGGCCGCACACGTGAGCG
CGACCTTGGCCGCTGAAGAGTTGAGCGGTTTGACAATCAGTCGGATTGATCCCGCCGAAGTGACCGAGGCTTATCGACAA
GAAGTCTTGCGGACCGCGGGAGATGGTTTGGATGAGCAAGGGCGAGCGTTGTTGGAAGAGGATCTTCGTTCTCCCTGCAC
GGAAGAGATCGCCGTGTTTCGAGCGTTCGCCGATGCCGTGGCGGAAGGCGAGGATGGCTTTGTCGTTCTCGACACCGCGC
CCACCGGTCACACGATTCTCCTGTTGGATTCGGCACTTGCATATCATCGCGAAGTTTCGCGGCAGACCAACGAGGTGCCT
GAAAGCGTTCGGGAATTGTTGCCACGCTTGCGAGATTCAGATTTCACGCGGGTGTTGGTGGTGACGCTGCCCGAGTCGAC
CCCGGTACATGAAGCTCAGCGGTTGCAACAGGATTTGCGGCGAGCGGAGATCGAGCCGTTTGCTTGGGTGGTCAATCAAT
CGCTTAGTCCGTTGGTTGTCAAGGATCGGATTCTGGTTGGGCGTCAACAAAACGAAGAGCCTTACCTGCGTGAGGTATTC
ACTCAGCACGCGAAGCAAGCGGTGATCATTCCCTGGCAACTTGACCCGCCAATCGGAATCGAAGGTTTGCGGGAGTTGAC
CGCAGACAAGGCTTCTTGCTAA

Protein sequence :
MHYLESPTRNLFFTGKGGVGKTSMACATAVRLADRGRRVLLVSTDPASNLDEVLGVTLSNKPTSVPAVDNLSAMNIDPEQ
AAAEYRERMVGPYRDVLPEAAVQSMEEQFSGSCTVEIAAFDEFARLLGDENATADFDHIVFDTAPTGHTLRLLTLPSAWS
GFMDENTSGTSCLGPLAGLQKQQAIYHSTVESLGDSSRTTLVLVTRPEASTLREADRTSDELRELGVENQALVINGTFEA
RDKSDPIANAMEQRCKEALMAMPSGLAQLQRTVVPLAPHGLVGIDALRLLGRTEPNGEMARNEIAGEERVSILEALPASA
LIDQLATQQHGVILTMGKGGVGKTTIAAAVAVALAERGLKVHLSTTDPAAHVSATLAAEELSGLTISRIDPAEVTEAYRQ
EVLRTAGDGLDEQGRALLEEDLRSPCTEEIAVFRAFADAVAEGEDGFVVLDTAPTGHTILLLDSALAYHREVSRQTNEVP
ESVRELLPRLRDSDFTRVLVVTLPESTPVHEAQRLQQDLRRAEIEPFAWVVNQSLSPLVVKDRILVGRQQNEEPYLREVF
TQHAKQAVIIPWQLDPPIGIEGLRELTADKASC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 4e-135 52
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 5e-101 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsA NP_868947.1 ArsA-catalytic subunit of arsenic oxyanion-translocating ATPase BAC0571 Protein 4e-135 52
arsA NP_868947.1 ArsA-catalytic subunit of arsenic oxyanion-translocating ATPase BAC0572 Protein 2e-133 52
arsA NP_868947.1 ArsA-catalytic subunit of arsenic oxyanion-translocating ATPase BAC0030 Protein 1e-135 52