Gene Information

Name : clpC (RB6751)
Accession : NP_867440.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3586111 - 3588690 bp
Length : 2580 bp
Strand : +
Note : PMID: 8016066 best DB hits: BLAST: pir:T36384; probable ATP-binding proteinase - Streptomyces; E=0.0 swissprot:P37571; CLPC_BACSU NEGATIVE REGULATOR OF GENETIC; E=0.0 ddbj:BAB03822.1; (AP001507) class III stress response-related; E=0.0 COG: BS_clpC; COG05

DNA sequence :
ATGTACGAACGGTTTACTGACCGAGCCAGGAAAGTCATGCAATTGGCTAACCAAGAGGCTCAACGATTCAATCACGAATA
CATCGGCACCGAACACATTTTGTTGGGTTTGGTGAAAGAGGGCAGCGGCGTTGCTGCCAACGTATTGAAAAATCTCGAGG
TCGATCTGCGAAAAATTCGCCTCGAAGTCGAGAAATTGGTGCAAAGCGGGCCTGAAATGGTGACCGTTGGCAAATTGCCA
CAGACACCACGTGCGAAGAAAGTCATCGAATATTCGATGGAAGAAGCTCGCAATCTCAATCACAGCTACGTCGGCACCGA
GCACATTCTGCTGGGTCTGCTGCGTGAGCAAGAAGGCGTCGCCGCTCAAGTTCTGATGAACTTGGGGCTGAAGCTGGAAG
ACGTCCGCGAAGAAGTCCTCAACCTGTTGGGACACGGTCTCGAAGGCGCTGAAGTTGGCGAACGCGGTGGCCGTGGCGGC
GACGGCGAAGGCAGCAGTGGCGGCAGCGGAAGCAGCAAGAGCGGCAAGAGCAAAACTCCTGCCCTGGATAGCTTTGGCCG
CGACCTGACCGAACTGGCAAAGAAAGGTGAACTTGATCCAGTCATCGGCCGCGAACGAGAAATCGAACGCGCCATCCAAA
TTCTTTGCCGTCGTACGAAAAACAACCCCGTCCTGCTGGGCGAAGCCGGTGTCGGTAAAACCGCCATCATCGAAGGCTTT
GCACAACGAGTTGTCGGCGGCGAAGTGCCTGAAATCTTGGCCGAGAAACGCATTGTCGTTCTCGACCTCGCCATGATGGT
CGCTGGTACCAAGTACCGCGGTCAATTCGAAGAACGCATCAAAGCGGTCATGACCGAAGTGCGTCGCGTCAAGAACACGA
TTCTTTTCATCGATGAACTTCACACCCTGGTCGGTGCCGGTGGTGCCGAAGGCGCAATCGACGCTGCCAACGTTCTGAAG
CCAGCTTTGGCTCGGGGCGAAATCCAGTGCATCGGTGCAACGACCCTGGACGAGTACCGGAAGTACATCGAAAAGGACAA
CGCCCTGGCTCGTCGTTTCCAAGAGATCATGGTCGAGCCAACCGGCAAGACGGAAACAATCGAAATCCTCAAAGGATTGC
GTGAACGCTACGAAGAGCACCACCGAGTTCAATTCACCGACGATGCCGTTGTTGCGGCCGTCGAAATGAGCGAACGCTAC
ATCACTGCGCGTTGCCTGCCTGACAAGGCTATCGACGTGATCGATGAAGCCGGTGCTCGTGTGCGTCTTCGCACCATGAC
TCGTCCACCAGACTTGAAAGAGATCGACGAGCAAGTCGAAACGCTGAACAAGGACAAAGAAGACGCGGTTGCCAACCAAG
ACTTCGAAAAAGCCGCCAACCTGCGTGATCAAGCCGAAAAACTTCGCAAGAAGAAAGAGCAGATCACTCAAGAGTGGCGT
GAAAAGAGTCAGCAAACCGATGGCGTCGTCGACGAAGAAATCATCGCAGAAGTCGTCAGCAAAATGACGGGCATTCCATT
GACTCGATTGTCAACGGAAGACTCCCTGCGTTTGCTGAAGATGGAAGAAGAACTGCACAAACGCGTCGTCAGCCAAAGCC
AAGCCGTCACGGCCGTTGCGAAAGCTGTTCGCCGAAGTCGCTCGGGATTGAAAGACCCCAAGCGTCCTACCGGTTCGTTC
ATCTTCGCCGGTCCAACCGGTGTCGGTAAAACGTTGCTCGCCAAGGCGCTCGCCGAATACATGTTCGGTGACGCGGATGC
GTTGGTGCACATCGACATGTCCGAGTACATGGAGAAACACAACGTTAGCCGTCTGATCGGTGCCCCTCCCGGATTCGTGG
GTTACGAAGAAGGTGGTCAGCTGACCGAGAAGATTCGCCGGCGTCCGTACGCGGTCGTGCTGTTCGACGAAATCGAAAAG
GCTCACCCCGATGTCTTCAACATGTTGTTGCAAGTCATGGAAGAAGGTCGCCTGACGGATTCGTTCGGACGAAACGTCGA
CTTCCGAAACACGATCTTGATCATGACCACCAACGCGGGTGCGGAAGCGATCAAGAACGAATCGGCATTCGGTTTCCAAA
AACCCGATGGCGATGCGAGCTACGACTCGATGAAGTCTCGTGTGATGGACCAAATTGAACGCGTCTTCCGTCCTGAGTTC
TTGAACCGTTTGGACGACACAATCATCTTCCGTCACTTGACCACGACCGACCTGAAGGGCGTGATCGACTTCGAACTGTC
CAAGGTTCGCGAACGTTTGCTCGATCGTGGCTTGGCCATCGATTTAAGCGACGAAGCGAAGGAGTTCTTGATCAAGAAAG
GCAGCAACCTCGATTACGGGGCTCGTCCACTTCGCCGTGCGATCGAGCAACGCATCGAAGACCCACTCGGCGAAGAATTG
CTGCGTGGTGCTTTCGAAGGCAAGGACACGATCATCATCGATGTTCACAAAGACGACAGTGGCAAGATCACACGTCTGAA
CTTCGAAGGCGAAAGCCGCGGCTGGGCAGACAGCGATTCCGAAGAGGAAACCGTGCCTGCCGCCAGCAGCGACGATCAAT
CGAAATCCGATGAGTCGTAA

Protein sequence :
MYERFTDRARKVMQLANQEAQRFNHEYIGTEHILLGLVKEGSGVAANVLKNLEVDLRKIRLEVEKLVQSGPEMVTVGKLP
QTPRAKKVIEYSMEEARNLNHSYVGTEHILLGLLREQEGVAAQVLMNLGLKLEDVREEVLNLLGHGLEGAEVGERGGRGG
DGEGSSGGSGSSKSGKSKTPALDSFGRDLTELAKKGELDPVIGREREIERAIQILCRRTKNNPVLLGEAGVGKTAIIEGF
AQRVVGGEVPEILAEKRIVVLDLAMMVAGTKYRGQFEERIKAVMTEVRRVKNTILFIDELHTLVGAGGAEGAIDAANVLK
PALARGEIQCIGATTLDEYRKYIEKDNALARRFQEIMVEPTGKTETIEILKGLRERYEEHHRVQFTDDAVVAAVEMSERY
ITARCLPDKAIDVIDEAGARVRLRTMTRPPDLKEIDEQVETLNKDKEDAVANQDFEKAANLRDQAEKLRKKKEQITQEWR
EKSQQTDGVVDEEIIAEVVSKMTGIPLTRLSTEDSLRLLKMEEELHKRVVSQSQAVTAVAKAVRRSRSGLKDPKRPTGSF
IFAGPTGVGKTLLAKALAEYMFGDADALVHIDMSEYMEKHNVSRLIGAPPGFVGYEEGGQLTEKIRRRPYAVVLFDEIEK
AHPDVFNMLLQVMEEGRLTDSFGRNVDFRNTILIMTTNAGAEAIKNESAFGFQKPDGDASYDSMKSRVMDQIERVFRPEF
LNRLDDTIIFRHLTTTDLKGVIDFELSKVRERLLDRGLAIDLSDEAKEFLIKKGSNLDYGARPLRRAIEQRIEDPLGEEL
LRGAFEGKDTIIIDVHKDDSGKITRLNFEGESRGWADSDSEEETVPAASSDDQSKSDES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC NP_867440.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 57
clpC NP_867440.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 3e-142 50