Gene Information

Name : metB (RB6443)
Accession : NP_867260.1
Strain : Rhodopirellula baltica SH 1
Genome accession: NC_005027
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 3393276 - 3394469 bp
Length : 1194 bp
Strand : +
Note : PMID: 9843488 best DB hits: BLAST: pir:T45483; cystathionine gamma-lyase homolog [imported] -; E=9e-93 pir:F83595; probable cystathionine gamma-lyase PA0400 [imported] -; E=1e-92 gb:AAG19548.1; (AE005045) cystathionine alpha synthase; MetB; E=3e-92 COG: P

DNA sequence :
ATGAGCTCTTCCAACTCGAACCACAAGTTTCGAACTCGCGCGATTCATGTCGGCAACGAAGTGGATCCACAAACCGGCGC
GGTTGTTCCGCCCATTCACTTCGCCAGTACGTTTCGACAACCCGGTGCGGGTGAGTGGGGACAATACGACTATTCGCGTA
GCGGCAACCCAACTCGAACGGGCCTGCAAGACACGCTCTCCTCGCTGGAAAATGGTTGTGGATCGCTTGCGTTTTCGTCC
GGCATGGCTGCCATTCACGCGGTCACCATGCTGTTGGAATCGGGCGATCACGTCGTCGCGGGATCTGATATCTACGGTGG
TGCCTACCGACTGCTACACCAGATCTGCAATCGCAGCGGTATCGAAGTCACCTTGGTCGACGTCACCGATTTACAGGCAA
TCGAAAACGCAATCACCGATCGGACCAAACTGATCTGGACCGAATCGATCGGTAATCCCCGCATGACGATTTCCGATTTA
CCAGCCATCGCTCGCCTAGCCAAATCCAAAGGAATCCTTTCGGGTGTCGACAACACATTCGGCACCCCGGCACTTTTGCG
GCCGCTGGACTTCGGCATCGACATCGTCATGCACTCGGCAACGAAGTACCTGGGCGGGCACAGCGATTGTCTGGGTGGCA
CCCTCGCGGTCGCGGATTCCGAGCTTTATGACCAACTCTATTTTGTCCAAAACGCGACTGGCGCCGTGCTCGACCCGATG
AGCAGTTTCTTGATCGCTCGCGGGCTGAAGACTCTCGATCTGCGTGTTCGCGAACAATCAAGAACGGCGCTTCGATTGGC
GAAATGGCTGGAAGCCCATCCCATGGTTCGATCGGTGCTTTACCCAGGCTTGCCATCGCACAACCAGCACGAACTTGCCC
GCCAACTGTTCGGACAACATCAAAGTGACTCAGAAGAAACACACTTCGGCGCTATGATCACGTTCGAACTGGATGCGACC
TTGGACCAAGTTCGCGAGGTTTGCCAATCGACCGAATTATTCCACCTGGCGGTCAGCCTCGGTGCGGTGGAATCCTTGAT
CGAGCAACCCGCCACGATGTCTCACGCTTCCTACGCTCCGGAAGCTCGTGCGGCTCACGGGATCACGGATTCATTGATCC
GTCTTTCGGTCGGCCTAGAATCTCCTTCCGATCTGGAAGCCGATTTGGAACGCGCGATCGCCATTATCGGGTAG

Protein sequence :
MSSSNSNHKFRTRAIHVGNEVDPQTGAVVPPIHFASTFRQPGAGEWGQYDYSRSGNPTRTGLQDTLSSLENGCGSLAFSS
GMAAIHAVTMLLESGDHVVAGSDIYGGAYRLLHQICNRSGIEVTLVDVTDLQAIENAITDRTKLIWTESIGNPRMTISDL
PAIARLAKSKGILSGVDNTFGTPALLRPLDFGIDIVMHSATKYLGGHSDCLGGTLAVADSELYDQLYFVQNATGAVLDPM
SSFLIARGLKTLDLRVREQSRTALRLAKWLEAHPMVRSVLYPGLPSHNQHELARQLFGQHQSDSEETHFGAMITFELDAT
LDQVREVCQSTELFHLAVSLGAVESLIEQPATMSHASYAPEARAAHGITDSLIRLSVGLESPSDLEADLERAIAIIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-74 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-75 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_867260.1 cystathionine gamma-lyase BAC0207 Protein 3e-61 42