Gene Information

Name : metB (HH0062)
Accession : NP_859593.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 67490 - 68641 bp
Length : 1152 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAGCACGCTTGATACATTGCTGATACACGGGGGAGCAACCACAGACCCACGAACAGGTGCAGTTAATATCCCTAT
CTATCAAACTTCTACCTATGCCCAAAGTGCGCTCGGAGAACATTTAGGATATGAATACTCACGCACTAAGAATCCAACGC
GAGATGGCATTGAGAGCCTTATTGCCCAATGTGAGGGTGGAAAATTTGGCTTCGCTTTTGCTTCGGGTATGGCAGCTATT
GGCACGATTTTAAGTCTCTTTCAAAGTGGAGATTGCATTATCATTTCAAATAATGTCTATGGTGGCACTTTTAGAATCTT
AGATAAAGTTTTTTCACATTTTAATATTAGCTATAAAATTGTTGATACACGTGATTTGAAAGCATTAGAATCTGCTATTA
CGCCTGAAGTCAAAGCTGTGCTTATTGAAACTCCAGCAAATCCGCTTCTAAGTGTTACGCCTTTAGAGCAGGTTGCTATA
CTTGCGAAAAAAAAAGGTATTTTAAGCATTGTAGATAATACCTTTATGACGCCTTATTTACAAAAACCTTTAGAGCTTGG
CATTGATATCGTGATGCATTCAGCAACAAAATATCTTGGAGGACATAGCGACCTTATAGCAGGACTCGTAGTTGTAAATG
ATTCTGCACTTGCAGAACGTATCGGCTTTTTACAAAATAGTATTGGGGGAGTGTTAGCACCTTTTGATAGCTTTTTGCTT
ATTCGCGGTATGAAAACACTCGGGGTGCGTCTCCAGCGCCATTGTGAAAATGCTCTCTTTTTAGCACAAGCACTTAGCGA
GCATAGTGGGGTTGAAAAGGTATATTATCCCGGACTTAAAAGTGATGAAGGCTATCAAATACAAAACTCACAGGCTCGTA
GCGGTGGAGGAATGCTAAGTTTTGAACTCAAAAAAAATTATGATTATAGAATCTTTTTTAAATCCACGCAAACAATCGTT
TTAGCCGAAAGTTTAGGAGGTGTAGAATCCTTGCTTTGCCACCCTGCATCTATGACTCATGCTTCAATCCCCAAAGATGT
GCGTGAGCGTATGGGTATAAGCGAACATCTTATCCGCCTTTCTGTTGGTATTGAATATGCACAAGATTTACTTGATGATT
TAAATCAAGCCATTAAAAAAGCAAAGGTATAG

Protein sequence :
MKSTLDTLLIHGGATTDPRTGAVNIPIYQTSTYAQSALGEHLGYEYSRTKNPTRDGIESLIAQCEGGKFGFAFASGMAAI
GTILSLFQSGDCIIISNNVYGGTFRILDKVFSHFNISYKIVDTRDLKALESAITPEVKAVLIETPANPLLSVTPLEQVAI
LAKKKGILSIVDNTFMTPYLQKPLELGIDIVMHSATKYLGGHSDLIAGLVVVNDSALAERIGFLQNSIGGVLAPFDSFLL
IRGMKTLGVRLQRHCENALFLAQALSEHSGVEKVYYPGLKSDEGYQIQNSQARSGGGMLSFELKKNYDYRIFFKSTQTIV
LAESLGGVESLLCHPASMTHASIPKDVRERMGISEHLIRLSVGIEYAQDLLDDLNQAIKKAKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-90 53
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-92 53
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-65 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_859593.1 cystathionine gamma-synthase BAC0207 Protein 7e-65 45