Gene Information

Name : fliI (HH0565)
Accession : NP_860096.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 542916 - 544292 bp
Length : 1377 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence : 
ATGTCATTGTCTCAAATCAAACAAAAACTTCAAAATAATATTAATCTTTCCCCAAGCTATGGACATCTTGTAAAAGTGAT
GCAAAATATGTTAGTGGCTAATGGCGTAAAACCTTCGGTGGGTGATATTGTGAAGATTCTCTCGCATTATGAAGCACCTT
CTTTGAAAGAATGCAATCAATCTTCAGAGGAATCTCTACAATTTGCTCATAATATGCAAACACATAATCTCGGTATGGTA
ATGGCTATTGAAGGGGAACATTTTTTCATTAGCCCCTTTTCATTTATAGAGGGACATAAATGTGGCGATAAAGTGGAGAT
TCTCAATCACGGATTGCATATTCCTGTGGGAGAGAATATGCTTGGACGAGTGATTAATCCACTTGGAGAACCCATTGATG
ACAAGGGAGCATTGCATACTTCTCATACTACACTGCTTATGCGTCCGCCTATAAGTGCGCTTAAAAGGGGGTTGATAAAT
GAAGTCTTTGAAGTGGGTGTAAAATCAATTGATGGAATCCTTACCTGTGGAAAGGGACAAAAAATGGGTATTTTTGCAGG
TTCAGGCGTAGGAAAATCCACACTTATGGGTATGATAGTGCGTGGTTCAAATGCACCTATTAAAGTAATCGCTCTTATTG
GGGAAAGAGGGAGAGAGGTCCCAGAGTTTATCCATAAAAATCTCAATAATGATTTAACCAATACCATTCTTGTGGTAGCT
ACAAGTGATGATTCTCCACTTATGCGTAAGTATGGAGCATTTAGTGCGATGGCGATCGCGGAGTATTTCAAATCACTCGG
TAATGATGTGCTTTTTATTATGGATTCTATAACGCGTTTTGCAATGGCACAAAGAGAAATTGGTTTGGCACTCGGCGAAC
CACCTACAAGCAAAGGTTATCCGCCATCTGTGCTTACACTTTTACCTCAATTAATGGAACGTGCGGGAAAGGAGGATGGT
GTAGGTTCTATCACAGCTTTTTTCACGGTGCTTGTTGAAGGAGATGATTTGAGTGACCCTGTTGCTGACCAAAGTCGCTC
TATCCTTGATGGACATATTGTGCTTAATCGTGACCTCACTGATATGGGAATTTATCCGCCTATTAATATTCTTAATTCTG
CTTCACGCGTTATTAATGACATTATTAGCCCTGAACATTTGCAAGTTATTCGTAAATTTCGGCGATTGTATTCGCTTCTT
AAGGAAAATGAAGTGCTTATACGCATTGGTGCATACCAAAGAGGTGCAGATAAAGAGCTTGATGAAGCTATTACAAAGCG
TTCGCTTATGGAATCATTTTTAAAACAGGAAATGAATGAGCAATGGAGCTTTGAACGCTCTTTTCAAGAGCTCTTGCATA
TTATGGAAGATGTGTAA

Protein sequence : 
MSLSQIKQKLQNNINLSPSYGHLVKVMQNMLVANGVKPSVGDIVKILSHYEAPSLKECNQSSEESLQFAHNMQTHNLGMV
MAIEGEHFFISPFSFIEGHKCGDKVEILNHGLHIPVGENMLGRVINPLGEPIDDKGALHTSHTTLLMRPPISALKRGLIN
EVFEVGVKSIDGILTCGKGQKMGIFAGSGVGKSTLMGMIVRGSNAPIKVIALIGERGREVPEFIHKNLNNDLTNTILVVA
TSDDSPLMRKYGAFSAMAIAEYFKSLGNDVLFIMDSITRFAMAQREIGLALGEPPTSKGYPPSVLTLLPQLMERAGKEDG
VGSITAFFTVLVEGDDLSDPVADQSRSILDGHIVLNRDLTDMGIYPPINILNSASRVINDIISPEHLQVIRKFRRLYSLL
KENEVLIRIGAYQRGADKELDEAITKRSLMESFLKQEMNEQWSFERSFQELLHIMEDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-76 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-78 48
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-82 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 8e-81 45
escN CAI43874.1 EscN protein Virulence LEE Protein 6e-81 45
escN AAC38383.1 EscN Virulence LEE Protein 4e-82 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-80 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-80 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 9e-82 45
escN AAC31513.1 L0034 Virulence LEE Protein 6e-82 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-82 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-82 45
escN AAK26715.1 EscN Virulence LEE Protein 3e-80 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-82 45
escN AAL57542.1 EscN Virulence LEE Protein 3e-80 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-73 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-74 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-73 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-73 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-74 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-74 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-74 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-55 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-62 42
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-80 41
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 41
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-80 41
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-80 41
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-80 41
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-78 41
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-78 41
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-79 41
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-79 41
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-61 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_860096.1 flagellum-specific ATP synthase VFG0048 Protein 7e-80 52
fliI NP_860096.1 flagellum-specific ATP synthase VFG0390 Protein 4e-78 50
fliI NP_860096.1 flagellum-specific ATP synthase VFG2144 Protein 1e-80 48
fliI NP_860096.1 flagellum-specific ATP synthase VFG2331 Protein 4e-77 47
fliI NP_860096.1 flagellum-specific ATP synthase VFG1254 Protein 6e-81 47
fliI NP_860096.1 flagellum-specific ATP synthase VFG1008 Protein 3e-63 46
fliI NP_860096.1 flagellum-specific ATP synthase VFG0730 Protein 2e-82 45
fliI NP_860096.1 flagellum-specific ATP synthase VFG0812 Protein 3e-82 45
fliI NP_860096.1 flagellum-specific ATP synthase VFG0515 Protein 5e-74 45
fliI NP_860096.1 flagellum-specific ATP synthase VFG0192 Protein 4e-78 45
fliI NP_860096.1 flagellum-specific ATP synthase VFG1778 Protein 1e-63 45
fliI NP_860096.1 flagellum-specific ATP synthase VFG2499 Protein 2e-81 44