Gene Information

Name : tktA (HH0026)
Accession : NP_859557.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 28808 - 30766 bp
Length : 1959 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCAAAAAACCTCACCACATATTACAGATGAAGATATACCTTTATTACAAAAAATGTCGCACACATTAGGGTTTTTGTG
TGCAGATATGGTGCAAAAAGCAAATAGCGGACATCCCGGCGCACCTATGGGACTTTCAGATATTGCAAGTGTGTTACATT
TTCATATTAATCTTGCTCCAACACAACCTCAATGGTTAAATCGAGATAGAATTATTTTTAGTGGAGGACACGCAAGCGCA
CTCGTATATTCGCTCCTTCATTTATGGGGTTTTGAGGTGAGTATGGCAGATTTGCACTCTTTTAGGCAATTAGATTCTAA
AACACCCGGACACCCTGAATATAGACATACTCAAGGTATTGAGATAACAACAGGTCCCCTTGGGCAAGGTATAGCAAATG
CAGTGGGTATGGCTATGGCAAGTAAATATGCACAGAATTTGTTTGGGCGGGAAATCATTTCGCATAATATATATTGTTTA
TGTGGCGATGGGGATTTACAGGAGGGTATCAGCTATGAAGCAGCTTCTTTAGCTGGACATCACGCTCTTTCAAATTTGAT
TCTTATTTATGATAGTAATCATATCACAATAGAAGGCGATACGCAACTTGCGATGAGTGAGGATATTGCTAAACGTTTTG
AAGCACAGGGTTGGGAAGTTTTAAGCTGCGATGGACACGACTATATACAAATTCACAATGTGCTTACCAATGCTAAAACT
TCTTCAAAACCCATACTTATTATTGCTCATACCATTATCGCTAAGAATGCCCTTAGTCTTGAGGGTAGTCATAAAGCACA
CGGCGCACCTTTGGGTGAAGAAATTATCGCCACAGCAAAGCAAAAACTTTCTTTTCCTGCAGAATCTTTTTATATACCTG
ATGATGTAGCACTTGCTTTTGGCACGATGAAGGAGCGTGGTGAGTTGAACTTTGCACAATGGTATAAAAATTATGAGAAT
CTCCCTCAAATTGCAAAAGAACGGCTTGATAAAATGAGAGAGCCCGATGTTTCCCATATTGTTTATCCACAATTTGCACT
TGGCGAAAGTATGGCTACACGTGTGAGTAATGGCAAGATTCTTAATAGTATTTCTCAAGCGTTAGAAGGATTTATTGGGG
GAAGTGCAGATTTAGCACCATCAAATAATACACAGCTACAAGATGAGGGTGATTTTCCGCAGGGTAAAAATTGGCATTTT
GGTATCCGAGAACACGCAATGGGTGCAATTTGTAATGGTGTGGCAAATTATGGCTTATTTTTACCTTTTTGCGCAACATT
TTTTGTTTTCAGTGATTATATGAGCCCAAGTGTGCGTGTAGCAAGCCTTATGAAAGCGAAAGTATATTATATTTGGACGC
ACGATAGTATAGGTGTGGGTGAAGATGGTGCGACACATCAGCCCATTGAACAATTAAGCCATTTTAGAGCAATGCCAAAT
CTCCTTGTTTTTCGTCCCGCTGATGCAAATGAGAATATTGCTTGTTGGCAGGTTGGCTTAGATTCCAAGCTACCTTGCGC
TTTTGTGCTTAGTCGTCAGAATCTCCCCGTTATTATGGAATCCACTCCTCAATTAAAAAAGCAAGTGCAAAAAGGCGGTT
ATGTATTGCGTTCGTGCGACAATGCAGTTATTACCCTTATGGCAAGCGGAAGTGAGGTAAGTCTTGCACTCAAAGCGTGT
GAAACACTAGAAGATTTAGGTATCAAAACACAAGTAGTAAGTGTACCTTGCCTTGATTTGCTTTTGGAACAACCTAAGGG
TTACATCAAAGAATTATGCGGAAAAAGTGCAGTGCTTGCTATTGAGGCTTCAAGAGGCTTAGAATGGTATGCAGTGGCTG
ATGAAGTGATTGGTATGCAGAGTTTTGGTGCTTCAGGGAAAGGCGAAGCCCTCTTTAATCGTTTTAATTTTAATATAGAT
TATATCATAGCTGCTGCACAAAAGCTTATTCAAAATTAA

Protein sequence :
MQKTSPHITDEDIPLLQKMSHTLGFLCADMVQKANSGHPGAPMGLSDIASVLHFHINLAPTQPQWLNRDRIIFSGGHASA
LVYSLLHLWGFEVSMADLHSFRQLDSKTPGHPEYRHTQGIEITTGPLGQGIANAVGMAMASKYAQNLFGREIISHNIYCL
CGDGDLQEGISYEAASLAGHHALSNLILIYDSNHITIEGDTQLAMSEDIAKRFEAQGWEVLSCDGHDYIQIHNVLTNAKT
SSKPILIIAHTIIAKNALSLEGSHKAHGAPLGEEIIATAKQKLSFPAESFYIPDDVALAFGTMKERGELNFAQWYKNYEN
LPQIAKERLDKMREPDVSHIVYPQFALGESMATRVSNGKILNSISQALEGFIGGSADLAPSNNTQLQDEGDFPQGKNWHF
GIREHAMGAICNGVANYGLFLPFCATFFVFSDYMSPSVRVASLMKAKVYYIWTHDSIGVGEDGATHQPIEQLSHFRAMPN
LLVFRPADANENIACWQVGLDSKLPCAFVLSRQNLPVIMESTPQLKKQVQKGGYVLRSCDNAVITLMASGSEVSLALKAC
ETLEDLGIKTQVVSVPCLDLLLEQPKGYIKELCGKSAVLAIEASRGLEWYAVADEVIGMQSFGASGKGEALFNRFNFNID
YIIAAAQKLIQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 7e-108 41
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-99 41