Gene Information

Name : hemC (HH1727)
Accession : NP_861258.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1653201 - 1654166 bp
Length : 966 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGCAAAGCAGAGCGGAGCAGATAGAGAGCTAGTTATTGGCTCACGTGGAAGTATATTGGCTTTATGGCAAGCTGAATA
TATCAAGTCTTGCCTTAAAGCTCAATGTGGTTTGCAATCTCGCATACAAATTATTAAAACTCGTGGTGATAAAATTCTTG
ATGTGCCTTTGGCAAAAATAGGTGGAAAGGGGCTTTTTACTAAAGAGTTAGAAGAAATGCTTTTAAGCAAAGATATTGAT
TTGGCTGTGCATAGCCTCAAAGATGTGCCTGTAGAATTTGTGCCTGAACTCGATTTAGCAGCTATTACTCAACGTGAGAG
TGCAAATGATTGTTTTTTGAGTGTAAATTATCCCAATCTTAATGCTTTACCACAAGGAGCAAAAGTAGGGACAACTTCCC
TACGCCGCTCAATGCAGATTAAAAAATATCGCTCTGATTTAGATACATTAAGTTTGCGTGGCAATGTGCAAACACGACTA
GAGAAACTCCATAATGGTGCATTTGATGCAATTATCCTCGCTCAAGCAGGAGTGAATAGGCTTAAAATCAATACACAAGA
TGTGCGTTATATCGTGCCCTTAGATTTTATGATACCTGCGATGGGGCAGGGTGCGCTTGGAATAGAAATGCGTAAGGATT
CTATATTTTTTGATAGAATTGCTGTGCTTAATGATAAGCAGAGTGCGCTTTGTGTGAGTGCAGAAAGGGCTTTTGTGAGG
ACATTAGAGGGTGGGTGTCAAGTGCCAATAGGCGTGTATGCACAATTTAGCAATAATAAACTCACACTTCAAGCTATAGT
AGGATTGCCTGATGGAAGTGAAGTATTACAAGATAGTGTCGAGGATTCTATAAATATAGATGATATAAATGCAAGCGAGA
ATCTAGGTATAGCATTTGCACAAAAATTTATTGATAAAGGTGCAAAAGAACTTCTTGAGCGAGCAGCAAAAATAGCATTT
GCATAA

Protein sequence :
MAKQSGADRELVIGSRGSILALWQAEYIKSCLKAQCGLQSRIQIIKTRGDKILDVPLAKIGGKGLFTKELEEMLLSKDID
LAVHSLKDVPVEFVPELDLAAITQRESANDCFLSVNYPNLNALPQGAKVGTTSLRRSMQIKKYRSDLDTLSLRGNVQTRL
EKLHNGAFDAIILAQAGVNRLKINTQDVRYIVPLDFMIPAMGQGALGIEMRKDSIFFDRIAVLNDKQSALCVSAERAFVR
TLEGGCQVPIGVYAQFSNNKLTLQAIVGLPDGSEVLQDSVEDSINIDDINASENLGIAFAQKFIDKGAKELLERAAKIAF
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-57 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-57 48