Gene Information

Name : thiC (HH1581)
Accession : NP_861112.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1509707 - 1511080 bp
Length : 1374 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGAACACAATGGGTGCAACAGCGTGCGGACGATAAAATTCGCACACAACTTCACTATGCAAAAAAAGGCATTATCAC
AAAAGAAATGGAATATGTAGCTAATATTGAAAATATAAGCGCTGAACTTATACGGCAAGAAATTGAACGTGGCAGACTGA
TTATTCCCGCAAATATCAATCATACCAATCTTAAACCTATGGGAATTGGCATAGCTACACGCACTAAAATTAATTCAAAT
ATTGGTAGCTCCTCACTTGCAAGCTCCATTGATGAAGAAGTAGAAAAAGTTAAAGTATCTATTAAATATGGTGCGGATAC
GATTATGGATTTAAGCACAGGTGGGGATTTAGATGAAATACGCACTGCAGTTATTCAAGCCTCAAGTGTGCCTATTGGAA
CGGTGCCTATATATCAGATTCTCTATGATGTAAAAAATGATATATTGCAGCTTGATATTGACACTATGCTTTCGGTGCTC
AAAAAACAAGCTAAACAAGGGGTAAGTTATTTCACTATTCATTGCGGATTTTTACTTTCACATATGCCATTTGTTGCTAA
ACGAAAAATGGGTATTGTCTCACGTGGTGGTAGCCTTATGGCAAGTTGGATGATGCACTACCACAAAGAAAATCCTTTTT
ATGAGTATTTTGATGAGATTCTCAAAATTTGCCAAGAATATGATGTATCTCTCTCGCTTGGAGATTCCTTGCGTCCGGGT
TGCTTGGCTGATGCGAGTGATGAGGCACAATTTGCCGAACTCAAAGTATTAGGTGAACTTGCTAAAAGAGCTTGGAAGGC
TGATGTGCAAGTAATGATAGAAGGACCCGGACACGTGCCGCTTAACCAAATTGAACGCAATGTTGAGCTTCAAAAACAAT
ATTGTAACCACGCACCTTTTTATGTGCTAGGACCTTTGGTTACAGACATTGCGGCAGGATATGACCATATCGCAAGTGCT
ATCGGTGCGTGTGTTGCCGCTTGGAAAGGAGTAGCAATGCTTTGTTATGTAACGCCAAAAGAACATTTAGGGCTTCCTAA
TGCCAAAGATGTGCGTGAGGGTATTTTAGCTTACAAAATTGCTGCACACGCTGCAGATATTGCTCGTGGGCGTATAGGTG
CGCGTGATAGAGATGATGCAATGAGTGATGCACGATATAGTTTTGATTGGAATAGACAATTTGAACTTGCCTTAGACCCA
GATAGAGCGCGTGAATACCACGATGAAGCCTTACCCCAAGAAGTATTTAAAGATGCCGAATTTTGCTCAATGTGTGGTCC
AAAATTCTGTAGCTATAAAATCTCACAAGATATTTTTAAAGCCCATAATGCTAAAGAATCTGAAGATACTCAACCTCTAG
CATCAAATCAATGA

Protein sequence :
MRTQWVQQRADDKIRTQLHYAKKGIITKEMEYVANIENISAELIRQEIERGRLIIPANINHTNLKPMGIGIATRTKINSN
IGSSSLASSIDEEVEKVKVSIKYGADTIMDLSTGGDLDEIRTAVIQASSVPIGTVPIYQILYDVKNDILQLDIDTMLSVL
KKQAKQGVSYFTIHCGFLLSHMPFVAKRKMGIVSRGGSLMASWMMHYHKENPFYEYFDEILKICQEYDVSLSLGDSLRPG
CLADASDEAQFAELKVLGELAKRAWKADVQVMIEGPGHVPLNQIERNVELQKQYCNHAPFYVLGPLVTDIAAGYDHIASA
IGACVAAWKGVAMLCYVTPKEHLGLPNAKDVREGILAYKIAAHAADIARGRIGARDRDDAMSDARYSFDWNRQFELALDP
DRAREYHDEALPQEVFKDAEFCSMCGPKFCSYKISQDIFKAHNAKESEDTQPLASNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-105 59
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-105 59
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 9e-101 55