Gene Information

Name : serS (HH1490)
Accession : NP_861021.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1426404 - 1427672 bp
Length : 1269 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATACAAAGGCATTGATAAATCAATTTGATGAAATAAAATCGCGACTTGCAATTAAAAAAGTAAGTGAAGAAAC
ATTGAGTGCTCTTAAAGATATGGCTCTTAAATATAAATCCTGCAAACAGGAGCTTGAAGAGTTACAAGCTTTTCAAAATA
AAACTTCAAAACTTTTTGGCGAATATAAAAGAGAGCAAAAAGATATTACAGCACTTAAAGTGGCGCTTGATGAGAATAAA
GTTAAGATGAGCACTTTAGAATCTACGCTAAAAGAGATAGAATCACATTTAGAAACACTTGCTTATGGGATACCGAATCT
ACCTGATGATGCCACGCCAGAGGGTGAGGATGAGAATGATAATGTTGAAATTAAAAAAGTGCTCTCTCCTCCACATTTTG
ATTTTGTTCCTAAAGAGCATTGGGAACTTGGTATTGCAAATGGTTGGATTGATTTTGAAGCAGGAGTAAAACTTGCTAAA
AGTCGTTTTAGTGTGTTGCGTGGAATGGGAGCAAAACTCAATCGCGCACTTATTAATTTTATGTTAGATTATAATGAAAA
AGCAGGTTTTGAATCTATTGTAACACCCGTAATTGTTAATGCACGAGCACTTTTTGGCACAGGACAGCTTCCAAAGTTTG
AAGAAGATATGTTTAAAGTAGATTCTCATTTTTGTGATGAACAAAGTGAGCACGATTTGTATCTTATCTCTACTTCAGAA
ATTACGCTTACTAATCTCTATCAAGATAGTATTATTCCAAGTGAGGAACTACCTATTATGCTCACAGCTCAAACACCTTG
TTTTCGTAAAGAAGCGGGAAGTGCAGGGCGAGATACGCGGGGTATGATACGCCAACATCAGTTTGATAAAGTTGAGCTTG
TGGCTATTACTCACCCAACCCAAAGTGCAGCAATGCAGGAGAAAATGGTGCAAACAGCAAGCGAGATTTTAAGTGAGCTT
AAGCTTCCACATCGTTTAATGCAGTTATGTGGTGGTGATTTGGGCTTTAGTGCAAGTAATACCATTGATATTGAAGTGTG
GCTTCCGGGACAAAATTGTTATCGTGAGATTAGCTCTATATCAAATACGCGTGATTTTCAAGCTCGTAGAGCGAAGATTC
GTTACAAAGAAAATGGTAAAAATGCCCTTGTGCATACACTTAATGGTTCATCTTTGGCAGTAGGACGCACACTTATTGCA
ATTATGGAAAATTATCAGCAAGTAGATGGGAGTGTAATGATTCCTGAAGTGCTACAAAAGTATCTATAA

Protein sequence :
MIDTKALINQFDEIKSRLAIKKVSEETLSALKDMALKYKSCKQELEELQAFQNKTSKLFGEYKREQKDITALKVALDENK
VKMSTLESTLKEIESHLETLAYGIPNLPDDATPEGEDENDNVEIKKVLSPPHFDFVPKEHWELGIANGWIDFEAGVKLAK
SRFSVLRGMGAKLNRALINFMLDYNEKAGFESIVTPVIVNARALFGTGQLPKFEEDMFKVDSHFCDEQSEHDLYLISTSE
ITLTNLYQDSIIPSEELPIMLTAQTPCFRKEAGSAGRDTRGMIRQHQFDKVELVAITHPTQSAAMQEKMVQTASEILSEL
KLPHRLMQLCGGDLGFSASNTIDIEVWLPGQNCYREISSISNTRDFQARRAKIRYKENGKNALVHTLNGSSLAVGRTLIA
IMENYQQVDGSVMIPEVLQKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-89 47