Gene Information

Name : smpB (HH0121)
Accession : NP_859652.1
Strain : Helicobacter hepaticus ATCC 51449
Genome accession: NC_004917
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 118056 - 118523 bp
Length : 468 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCCCATACGAGTGATTGCAAAAAATAAAAAAGCATATTTTGATTATGAGATTCTTCAAAGTTTAGAAAGTGGTATTGT
GTTGCAAGGAAGCGAAGTAAAAAGTATTCGCGCAGGACGAGTAAATCTTAAAGATAGTTTTATAAAAATCATACGCGGAG
AAGCCTTTTTGTTTAATGCTCATATTTCATTTTTACAAACGACTTATACGCATTTTAAGCCCAATGAACGCAGAGAAAGG
AAACTTTTGCTTCATAAAAAAGAGATTGATAAATTGTTTGGGAGTGTAAGCAAAGAATCTTTAAGCATTGTTCCATTAAA
CATTTATTTTAATCAAAAAAATAAAATTAAACTTTGTATTGCACTTGTGCGAGGGAAAAAATTGCACGATAAGCGAGAGA
GCATTAAGAAAAAAATGCTTGAGCGTGAAGCAAGAGCGCATATGAAAAGCTATGGCAAAAAGTTGTAG

Protein sequence :
MPIRVIAKNKKAYFDYEILQSLESGIVLQGSEVKSIRAGRVNLKDSFIKIIRGEAFLFNAHISFLQTTYTHFKPNERRER
KLLLHKKEIDKLFGSVSKESLSIVPLNIYFNQKNKIKLCIALVRGKKLHDKRESIKKKMLEREARAHMKSYGKKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-21 44
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-23 44
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-22 42