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Name : sepA (CP0070) Accession : NP_858203.1 Strain : Genome accession: NC_004851 Putative virulence/resistance : Virulence Product : extracellular serine protease SepA Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG3468 EC number : - Position : 52745 - 56839 bp Length : 4095 bp Strand : - Note : - DNA sequence : ATGAACAAAATATATTATCTTAAGTATTGCCATATAACCAAAAGCCTGATTGCTGTCTCCGAACTGGCCCGCAGGGTTAC CTGCAAAAGCCATCGCAGACTTTCACGTCGGGTTATTCTTACGTCTGTTGCAGCTTTATCACTTTCCTCGGCATGGCCAG CTCTGTCAGCAACGGTCAGTGCAGAGATCCCTTATCAGATATTCCGCGACTTTGCCGAGAATAAAGGTCAGTTTACGCCG GGGACCACGAATATTTCCATTTACGACAAGCAGGGCAATCTGGTCGGTAAACTTGATAAAGCCCCGATGGCTGATTTCAG TAGTGCCACTATTACTACCGGTAGCCTGCCTCCGGGAGACCATACACTTTACTCCCCTCAGTATGTGGTTACCGCCAAAC ATGTCAGCGGTTCTGACACGATGAGCTTCGGATACGCCAAAAACACCTATACTGCGGTTGGTACAAATAATAATAGCGGT CTTGATATTAAAACCCGCCGCCTGAGTAAACTGGTGACAGAGGTGGCGCCGGCAGAAGTGTCTGACATCGGGGCTGTGAG CGGTGCCTATCAGGCCGGCGGACGCTTTACTGAATTCTATCGCCTTGGGGGGGGGATGCAGTACGTCAAAGACAAAAATG GTAATCGCACCCAAGTGTATACCAATGGCGGATTTCTTGTTGGGGGAACCGTCAGCGCGCTGAACTCCTATAACAACGGA CAGATGATTACAGCTCAGACCGGTGACATTTTTAATCCCGCGAATGGACCTCTGGCTAATTATCTGAATATGGGGGACAG CGGCTCCCCCCTGTTTGCTTATGATTCCCTGCAAAAAAAATGGGTACTGATTGGCGTGCTTTCCTCAGGAACTAACTATG GAAATAACTGGGTCGTCACCACTCAGGATTTCCTTGGTCAGCAACCGCAAAATGATTTTGACAAAACTATAGCCTACACC TCTGGTGAAGGAGTACTGCAGTGGAAATATGATGCGGCTAATGGCACCGGCACACTGACTCAGGGAAACACGACTTGGGA TATGCATGGAAAGAAAGGAAATGATCTGAACGCAGGAAAAAACCTCCTGTTCACCGGCAATAATGGCGAGGTCGTTCTGC AGAATTCCGTTAATCAGGGAGCTGGGTATCTGCAGTTTGCCGGCGATTACAGGGTGTCCGCCCTGAACGGCCAGACATGG ATGGGGGGCGGGATTATCACCGATAAAGGAACCCACGTTCTGTGGCAGGTGAACGGAGTTGCCGGTGATAACCTGCATAA AACTGGCGAAGGTACCCTGACAGTAAACGGGACCGGTGTGAATGCAGGCGGACTCAAGGTGGGGGACGGTACCGTTATTC TCAACCAGCAGGCGGATGCTGACGGAAAGGTACAGGCTTTCAGCTCTGTTGGTATTGCCAGCGGTCGTCCGACAGTTGTG CTTTCTGACTCACAGCAAGTTAATCCGGATAATATTTCGTGGGGATACCGTGGAGGACGTCTGGAACTGAATGGTAATAA TCTGACCTTTACCCGTCTTCAGGCGGCTGACTACGGGGCCATCATTACCAATAACAGTGAGAAAAAATCAACGGTAACAC TCGACCTTCAGACATTAAAAGCCAGTGACATCAATGTACCGGTTAATACTGTCAGTATTTTTGGGGGGAGAGGAGCGCCG GGAGACCTATATTATGACAGTTCTACCAAGCAATATTTCATCCTGAAAGCGAGTTCATATTCCCCGTTCTTCTCCGATCT GAACAACAGCAGTGTCTGGCAGAATGTCGGAAAAGATCGTAATAAAGCCATTGATACTGTGAAGCAACAAAAAATTGAGG CCAGCAGCCAGCCTTATATGTATCACGGCCAACTAAACGGCAATATGGATGTGAATATTCCGCAGCTCTCAGGTAAGGAT GTACTGGCTCTTGATGGTTCAGTTAACCTGCCAGAAGGTTCGATAACCAAGAAGTCCGGCACGCTGATATTCCAGGGTCA TCCAGTTATTCATGCTGGAACGACGACTTCTTCCAGCCAGAGCGACTGGGAAACCCGTCAGTTTACGCTGGAAAAACTGA AACTCGATGCGGCAACATTCCATCTGTCCAGAAACGGCAAGATGCAGGGAGATATTAACGCCACCAATGGAAGTACAGTC ATTCTGGGAAGTAGCCGTGTCTTTACTGACAGGAGTGACGGAACCGGTAATGCGGTCTTCTCTGTTGAAGGGAGTGCCAC TGCAACCACAGTTGGTGACCAGAGTGATTACAGCGGAAATGTTACGCTGGAAAATAAATCATCCCTGCAAATCATGGAGA GATTCACCGGTGGTATTGAGGCTTATGATAGCACCGTGAGTGTGACCTCTCAGAATGCTGTTTTTGACCGTGTTGGCAGC TTTGTCAACAGCAGCCTGACCCTCGGAAAAGGAGCAAAACTTACGGCTCAGAGCGGTATTTTCAGCACCGGGGCTGTGGA TGTAAAAGAAAATGCTTCTCTGACCCTGACGGGGATGCCTTCTGCGCAGAAACAGGGGTATTACTCACCCGTAATTTCTA CAACAGAAGGGATTAACCTCGAAGATAACGCCAGCTTTTCTGTTAAAAATATGGGCTATCTGAGTTCGGATATTCATGCA GGAACCACTGCGGCAACCATTAATCTGGGAGACAGTGATGCTGATGCAGGGAAGACGGACTCTCCGTTATTCAGCTCCTT AATGAAGGGATATAACGCTGTTCTGAGAGGCAGTATTACGGGGGCACAGAGTACGGTAAATATGATCAATGCTCTGTGGT ACTCTGACGGAAAATCAGAGGCCGGTGCACTGAAGGCTAAGGGCTCGCGAATTGAACTGGGGGACGGGAAACACTTTGCC ACTTTACAAGTAAAAGAGCTTTCTGCAGATAATACCACGTTCCTGATGCATACCAACAACAGCCGGGCTGACCAGTTGAA TGTCACAGACAAACTGTCAGGCAGTAATAATAGCGTCCTGGTTGACTTTTTAAACAAACCAGCCAGTGAAATGAGCGTGA CGTTAATTACCGCACCGAAAGGGAGTGATGAGAAAACGTTCACTGCCGGTACGCAGCAGATTGGTTTCAGTAACGTTACG CCAGTAATCAGCACGGAAAAAACGGATGATGCCACAAAATGGGTGCTGACAGGATATCAGACTACCGCTGATGCCGGAGC CTCGAAAGCCGCAAAAGACTTTATGGCATCAGGTTATAAGTCCTTCCTTACAGAGGTCAATAACCTGAACAAACGTATGG GTGACCTGCGGGATACTCAGGGGGATGCCGGTGTCTGGGCACGCATAATGAATGGTACCGGTTCGGCAGATGGTGACTAC AGCGATAACTACACTCACGTTCAGATTGGTGTCGACAGAAAGCATGAGCTGGACGGTGTGGATTTATTTACGGGGGCATT GCTGACCTATACGGACAGCAATGCAAGCAGCCACGCATTCAGTGGAAAAAACAAATCCGTGGGTGGCGGTCTGTATGCCT CTGCACTCTTTAATTCCGGAGCTTATTTTGACCTGATTGGTAAATATCTCCATCATGATAATCAGCACACGGCGAATTTT GCCTCACTGGGAACAAAAGACTACAGCTCTCATTCCTGGTATGCCGGTGCTGAAGTTGGTTATCGTTACCACCTGACGAA AGAGTCCTGGGTGGAGCCACAGATAGAGCTGGTTTACGGTTCTGTATCAGGAAAAGCTTTTAGCTGGGAAGACCGGGGAA TGGCTCTGAGCATGAAAGACAAGGATTATAACCCACTGATTGGCCGTACTGGTGTTGACGTGGGAAGAGCCTTCTCCGGA GACGACTGGAAAATCACAGCTCGAGCCGGGCTGGGTTATCAGTTCGACCTGCTGGCGAACGGAGAAACGGTTCTGCAGGA TGCTTCCGGAGAGAAACGTTTCGAAGGTGAAAAAGATAGCAGGATGCTGATGACGGTAGGGATGAATGCGGAAATTAAGG ATAATATGCGTTTGGGACTGGAGCTGGAGAAATCAGCGTTCGGGAAATATAATGTGGATAATGCGATAAACGCCAACTTC CGTTATGTTTTCTGA Protein sequence : MNKIYYLKYCHITKSLIAVSELARRVTCKSHRRLSRRVILTSVAALSLSSAWPALSATVSAEIPYQIFRDFAENKGQFTP GTTNISIYDKQGNLVGKLDKAPMADFSSATITTGSLPPGDHTLYSPQYVVTAKHVSGSDTMSFGYAKNTYTAVGTNNNSG LDIKTRRLSKLVTEVAPAEVSDIGAVSGAYQAGGRFTEFYRLGGGMQYVKDKNGNRTQVYTNGGFLVGGTVSALNSYNNG QMITAQTGDIFNPANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSGTNYGNNWVVTTQDFLGQQPQNDFDKTIAYT SGEGVLQWKYDAANGTGTLTQGNTTWDMHGKKGNDLNAGKNLLFTGNNGEVVLQNSVNQGAGYLQFAGDYRVSALNGQTW MGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILNQQADADGKVQAFSSVGIASGRPTVV LSDSQQVNPDNISWGYRGGRLELNGNNLTFTRLQAADYGAIITNNSEKKSTVTLDLQTLKASDINVPVNTVSIFGGRGAP GDLYYDSSTKQYFILKASSYSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIEASSQPYMYHGQLNGNMDVNIPQLSGKD VLALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTTTSSSQSDWETRQFTLEKLKLDAATFHLSRNGKMQGDINATNGSTV ILGSSRVFTDRSDGTGNAVFSVEGSATATTVGDQSDYSGNVTLENKSSLQIMERFTGGIEAYDSTVSVTSQNAVFDRVGS FVNSSLTLGKGAKLTAQSGIFSTGAVDVKENASLTLTGMPSAQKQGYYSPVISTTEGINLEDNASFSVKNMGYLSSDIHA GTTAATINLGDSDADAGKTDSPLFSSLMKGYNAVLRGSITGAQSTVNMINALWYSDGKSEAGALKAKGSRIELGDGKHFA TLQVKELSADNTTFLMHTNNSRADQLNVTDKLSGSNNSVLVDFLNKPASEMSVTLITAPKGSDEKTFTAGTQQIGFSNVT PVISTEKTDDATKWVLTGYQTTADAGASKAAKDFMASGYKSFLTEVNNLNKRMGDLRDTQGDAGVWARIMNGTGSADGDY SDNYTHVQIGVDRKHELDGVDLFTGALLTYTDSNASSHAFSGKNKSVGGGLYASALFNSGAYFDLIGKYLHHDNQHTANF ASLGTKDYSSHSWYAGAEVGYRYHLTKESWVEPQIELVYGSVSGKAFSWEDRGMALSMKDKDYNPLIGRTGVDVGRAFSG DDWKITARAGLGYQFDLLANGETVLQDASGEKRFEGEKDSRMLMTVGMNAEIKDNMRLGLELEKSAFGKYNVDNAINANF RYVF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pic | NP_838464.1 | serine protease precurser | Virulence | SHI-1 | Protein | 0.0 | 58 |
| she | AAB58244.1 | mucinase | Virulence | SHI-1 | Protein | 0.0 | 56 |
| pic | NP_708747.3 | serine protease | Not tested | SHI-1 | Protein | 0.0 | 56 |
| pic | AAK00464.1 | Pic | Virulence | SHI-1 | Protein | 0.0 | 56 |
| unnamed | CAC39286.1 | hypothetical protein | Not tested | LPA | Protein | 0.0 | 54 |
| vat | YP_851472.1 | vacuolating autotransporter | Not tested | PAI III APEC-O1 | Protein | 0.0 | 47 |
| unnamed | CAD66214.1 | putative hemoglobin protease | Not tested | PAI III 536 | Protein | 0.0 | 47 |
| vat | AAO21903.1 | vacuolating autotransporter toxin | Virulence | Not named | Protein | 0.0 | 46 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| sepA | NP_858203.1 | extracellular serine protease SepA | VFG0861 | Protein | 0.0 | 56 |
| sepA | NP_858203.1 | extracellular serine protease SepA | VFG0903 | Protein | 0.0 | 56 |
| sepA | NP_858203.1 | extracellular serine protease SepA | VFG0635 | Protein | 0.0 | 56 |
| sepA | NP_858203.1 | extracellular serine protease SepA | VFG0904 | Protein | 0.0 | 47 |
| sepA | NP_858203.1 | extracellular serine protease SepA | VFG1689 | Protein | 0.0 | 47 |
