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Name : mxiA (CP0147) Accession : NP_858280.1 Strain : Genome accession: NC_004851 Putative virulence/resistance : Virulence Product : Mxi-Spa secretion machinery protein MxiA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4789 EC number : - Position : 126749 - 128809 bp Length : 2061 bp Strand : + Note : - DNA sequence : GTGATCCAGTCTTTTCTTAAGCAAGTAAGTACTAAGCCTGAATTAATTATATTAGTGCTTATGGTTATGATCATTGCTAT GTTGATCATACCATTACCTACATACCTTGTTGATTTTTTAATAGGGCTTAATATTGTACTTGCTATTCTCGTTTTTATGG GATCATTTTATATTGAAAGAATATTGAGTTTTTCTACATTCCCTTCGGTTTTGTTGATAACGACATTATTTCGTCTCGCT TTATCAATAAGTACTAGTCGACTAATTTTAGTTGATGCGGATGCGGGTAAAATTATTACTACATTTGGCCAGTTTGTCAT TGGTGATAGTCTGGCTGTAGGTTTTGTTATTTTTTCAATAGTAACTGTTGTGCAGTTCATTGTTATAACAAAAGGATCTG AAAGGGTTGCGGAGGTAGCTGCTCGCTTTTCTCTTGACGGTATGCCGGGGAAACAAATGAGCATTGATGCGGATTTAAAG GCTGGAATTATTGATGCCGCAGGAGCTAAAGAAAGACGCAGTATTCTGGAACGTGAGAGTCAATTGTATGGTTCATTTGA TGGAGCAATGAAGTTCATTAAAGGTGATGCAATTGCTGGCATCATTATTATTTTTGTCAATTTAATAGGAGGTATTTCTG TTGGTATGAGTCAACATGGAATGTCCCTATCTGGTGCATTATCTACTTATACCATACTAACTATTGGTGACGGATTGGTC TCTCAGATTCCTGCTCTGTTAATTTCTATAAGTGCAGGATTTATCGTTACAAGAGTTAATGGTGATAGCGATAATATGGG ACGTAACATAATGTCCCAGATATTTGGGAATCCTTTTGTTCTCATTGTTACATCAGCTCTTGCCTTGGCGATAGGGATGT TGCCAGGTTTTCCGTTTTTTGTTTTTTTCCTGATAGCAGTTACTTTGACGGCTTTATTCTATTATAAAAAGGTCGTAGAA AAAGAAAAAAGTCTGTCTGAGTCTGATTCTAGTGGCTATACTGGTACATTTGATATTGATAATAGCCATGACTCATCTTT GGCAATGATAGAAAATCTGGATGCTATTAGTTCAGAAACCGTTCCTTTAATTTTATTATTTGCCGAAAATAAGATAAATG CAAATGATATGGAAGGTCTTATTGAAAGGATAAGAAGTCAGTTCTTTATTGATTATGGTGTCAGGCTTCCAACTATTTTA TATAGAACAAGCAATGAGCTTAAGGTCGATGATATTGTTTTGTTAATAAATGAGGTGCGTGCCGATAGTTTTAATATATA CTTTGACAAAGTGTGTATTACAGATGAAAATGGAGATATAGATGCTCTAGGTATTCCTGTTGTTTCAACTTCATATAATG AACGTGTTATTTCTTGGGTAGACGTTTCATATACAGAAAATCTAACTAATATTGATGCTAAAATTAAAAGTGCTCAAGAT GAATTTTATCACCAGTTGTCACAAGCTTTATTAAACAACATAAATGAGATTTTTGGTATACAAGAAACAAAAAATATGTT AGATCAGTTTGAAAATCGGTATCCTGATCTATTAAAGGAAGTCTTCCGACATGTGACTATACAGAGAATTTCTGAGGTAT TACAAAGATTGCTTGGAGAAAATATTTCTGTTCGCAATTTAAAACTTATTATGGAGTCTTTGGCGCTTTGGGCTCCCAGA GAAAAAGATGTCATAACATTAGTTGAACATGTCCGTGCATCACTTTCTAGGTATATTTGTAGTAAAATAGCTGTTTCTGG TGAGATTAAAGTTGTGATGCTTTCCGGATATATTGAGGATGCAATAAGAAAAGGGATAAGGCAAACCTCTGGTGGCTCTT TCTTGAATATGGATATAGAGGTTTCGGATGAGGTAATGGAAACTTTAGCACATGCTTTGAGAGAATTGAGAAATGCAAAA AAAAATTTCGTTCTTTTGGTATCAGTAGATATACGTAGGTTTGTTAAAAGACTTATAGATAACAGATTTAAGAGTATACT CGTTATATCGTATGCTGAGATTGATGAAGCATATACCATTAATGTATTAAAGACTATTTAG Protein sequence : MIQSFLKQVSTKPELIILVLMVMIIAMLIIPLPTYLVDFLIGLNIVLAILVFMGSFYIERILSFSTFPSVLLITTLFRLA LSISTSRLILVDADAGKIITTFGQFVIGDSLAVGFVIFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK AGIIDAAGAKERRSILERESQLYGSFDGAMKFIKGDAIAGIIIIFVNLIGGISVGMSQHGMSLSGALSTYTILTIGDGLV SQIPALLISISAGFIVTRVNGDSDNMGRNIMSQIFGNPFVLIVTSALALAIGMLPGFPFFVFFLIAVTLTALFYYKKVVE KEKSLSESDSSGYTGTFDIDNSHDSSLAMIENLDAISSETVPLILLFAENKINANDMEGLIERIRSQFFIDYGVRLPTIL YRTSNELKVDDIVLLINEVRADSFNIYFDKVCITDENGDIDALGIPVVSTSYNERVISWVDVSYTENLTNIDAKIKSAQD EFYHQLSQALLNNINEIFGIQETKNMLDQFENRYPDLLKEVFRHVTIQRISEVLQRLLGENISVRNLKLIMESLALWAPR EKDVITLVEHVRASLSRYICSKIAVSGEIKVVMLSGYIEDAIRKGIRQTSGGSFLNMDIEVSDEVMETLAHALRELRNAK KNFVLLVSVDIRRFVKRLIDNRFKSILVISYAEIDEAYTINVLKTI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| invA | NP_461817.1 | needle complex export protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | YP_217815.1 | invasion protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | NP_457290.1 | possible secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | NP_806499.1 | virulence-associated secretory protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| ECs3731 | NP_311758.1 | EivA | Not tested | LIM | Protein | 3e-178 | 61 |
| invA | AAS66860.1 | InvA | Not tested | SSR-2 | Protein | 3e-170 | 57 |
| ysaV | AAS66840.1 | YsaV | Not tested | SSR-1 | Protein | 4e-148 | 53 |
| unnamed | AAL06368.1 | EscV | Virulence | LEE | Protein | 2e-99 | 42 |
| escV | YP_003223476.1 | translocator EscV | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | CAC81861.1 | EscV protein | Virulence | LEE II | Protein | 3e-98 | 42 |
| escV | YP_003236089.1 | putative translocator EscV | Virulence | LEE | Protein | 5e-99 | 42 |
| escV | AAK26714.1 | EscV | Virulence | LEE | Protein | 1e-98 | 42 |
| escV | AAL57541.1 | EscV | Virulence | LEE | Protein | 1e-98 | 42 |
| escV | CAI43875.1 | EscV protein | Virulence | LEE | Protein | 1e-98 | 42 |
| escV | YP_003232152.1 | T3SS structure protein EscV | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | AFO66414.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 3e-96 | 41 |
| escV | AFO66296.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 2e-96 | 41 |
| escV | AAC31514.1 | L0035 | Virulence | LEE | Protein | 4e-99 | 41 |
| escV | ACU09459.1 | EscV protein | Virulence | LEE | Protein | 4e-99 | 41 |
| escV | NP_290269.1 | hypothetical protein | Virulence | LEE | Protein | 6e-99 | 41 |
| ECs4569 | NP_312596.1 | hypothetical protein | Virulence | LEE | Protein | 6e-99 | 41 |
| escV | AAC38382.1 | EscV | Virulence | LEE | Protein | 7e-99 | 41 |
| lssD | AAO18050.1 | LssD | Virulence | TTSS locus | Protein | 1e-113 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG1006 | Protein | 0.0 | 100 |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG0557 | Protein | 0.0 | 65 |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG1780 | Protein | 2e-149 | 51 |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG0729 | Protein | 4e-99 | 41 |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG0813 | Protein | 3e-99 | 41 |
| mxiA | NP_858280.1 | Mxi-Spa secretion machinery protein MxiA | VFG0384 | Protein | 9e-110 | 41 |
