Gene Information

Name : serS (AM759)
Accession : YP_153958.2
Strain : Anaplasma marginale St. Maries
Genome accession: NC_004842
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 695774 - 697063 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCACGACATTGAGCTTATTAAAAAAGACCCTGAGCTGTTTGACAGGGCCATGATATCCCGTGGCTTTGGTGAGCAGGC
GGAAAAAATCATCGAATTAGATCTAAAAAAGAGGGGGGAGCTGTCTACTTTGTATTCCCTACGAGAACAACGAAACGCAG
TAACGCGGGAGGTGGCCCTCTTGAAGCGTAGCGGAATCGAGTGCACACCCCAAATCGAGGCCTCCAAGAAACTGGCTGAA
GAGATCGCAACACTTGAGCACAGTATTAAGGAGGACACGAAACTTTCCAACTTACTTGAAAGCCTCCCTAATGTCCCTGA
CCCTATAGTGCCGGTAGGCAAAGATGAGAGTCATAACGTTGAAGTGCGGTCACACGGACAGAGGAGAGATTTCGCTTTTG
GTATCAGGCCCCATTATGAGCTTGGCGAAATGCTGAATTTGTTGGATTTCAAGCGCGCCGCAGTGCTGTCTGGAGCCAGA
TTTTCCATTTTAAAAGGTCAGCTTGCGGAGCTAGAGAGAGCACTTGCAAGCTTTATGCTAGATATGCACACCAAGGAGTT
TGGGTATACAGAAATATCACATCCAGTCTTGGTGAACGAGCGCACAATGTACAACGTGGGTCAATTACCAAAGTTTCACG
ATGATTCTTTCCGCACTACAAACAACTTCAGGCTTGCACCGACCAGTGAAGTTGCACTGGCTAATCTGGTATCGGGAACA
ACGCTCCCACGTGACTCCTTGCCGATGAGATTTACGGCATATTCCCAATGCTTTAGGGCAGAAGCTGGAAGTGCCGGCCT
AGATACGCGGGGCATGATGCGACAGCATCAATTTGGCAAGGTGGAGCTCGTTAGTATTACTACAAGCGACGCATCAAATG
CTGAGCTTGAGAGGATGACTTCAATCGCGGAAGAGGTACTGAAGAGGCTAGAACTCCCGTATAGAGTTATGCTATTATGT
TCAGGGGATATGGGGTTTTCCGCAAGCATTTCTTACGACTTGGAAGTGTGGATGCCGGCCCAGGACAAGTATAGGGAGAT
TTCCAGCTGCTCAAACTGTAGGGATTTTCAAGCCCGAAGGATGGGGGCGAAGTATTTCTTCTTCGAGAACAAGAAAAAGC
ACTCCACACTGGTACATACCCTAAACGGTTCTGCGCTCGCTATCGGGAGGACAATAGCCGCTATCATGGAGAACTATCAG
AACGAAGATGGATCCATCACTATCCCAGACGTGCTCAGAAAGTACACCGGAGCAAGCGCAATAATGCGCGCAGAAGATGC
CCTGCCTTGA

Protein sequence :
MHDIELIKKDPELFDRAMISRGFGEQAEKIIELDLKKRGELSTLYSLREQRNAVTREVALLKRSGIECTPQIEASKKLAE
EIATLEHSIKEDTKLSNLLESLPNVPDPIVPVGKDESHNVEVRSHGQRRDFAFGIRPHYELGEMLNLLDFKRAAVLSGAR
FSILKGQLAELERALASFMLDMHTKEFGYTEISHPVLVNERTMYNVGQLPKFHDDSFRTTNNFRLAPTSEVALANLVSGT
TLPRDSLPMRFTAYSQCFRAEAGSAGLDTRGMMRQHQFGKVELVSITTSDASNAELERMTSIAEEVLKRLELPYRVMLLC
SGDMGFSASISYDLEVWMPAQDKYREISSCSNCRDFQARRMGAKYFFFENKKKHSTLVHTLNGSALAIGRTIAAIMENYQ
NEDGSITIPDVLRKYTGASAIMRAEDALP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-92 48