Gene Information

Name : hemC (AM700)
Accession : YP_153925.1
Strain : Anaplasma marginale St. Maries
Genome accession: NC_004842
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 638378 - 639289 bp
Length : 912 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTATGCTCCTGTGGTCAGGCTGGGAACAAGAGGAAGCACGCTGGCACTAATACAAGCAGAGGAGGTCAAAGCCGCAAT
TGCAGCCCACTTTCCTGAGGTCCGAGTGGATGTTACCAAGATAAAAACGTCTGGGGATATAAAGGTTGACAGGCCACTGT
GTGACATTGGCGGCAAGGGCCTGTTCATCAAAGAGATAGAAGAGGCCCTGTTGGCCAATAAGATAGACATTGCCGTACAC
TCGGCCAAGGATGTTCCGGGCTTTTATTCCGAAAACTTAGACATGCCGTGCGTACTCAAAAGAAGATCTCCCATGGACGT
TTTTATATCTGTAAAGTACAAAAGCCTAAACTCCTTACCCGCCGGAGCAAAAATCGGCACCTCATCGATCAGAAGGAAGG
TGCAGCTTCTCGCTTTCAGACCAGACCTGGAAATAACCCCCATGCGGGGCAATGTTGACACCAGAATCGCTAAGGTACAA
TCTGGCGAGTGCGACGGTATAGTGCTGGCTGAGGCTGGGGTGGACAGGATATCTGCACGTGCTAAGATCACCGAGGTATT
ACATCCAGACGTGATGTTGGGGGCCGTAGGCCAGGGGGCAATATGCGTTCAGTGTAGAAAAAGCGACGAAGGAATAGTGC
GTATGCTCGCAAAGTTGAACGACCATGAGTCATTCACGGCCGTGCTGGCTGAGCGAAGCTTCATGAAGGCTGTGAACGGC
TCCTGCCACACACCTTTAGCTGCAATGGCTAGGTATGTGGACAGTGGCCTGATGTCGATGAAGTGCATGCTAGCGCATGA
CTCTCGTACCATGGTATCCGCAGAACGCACTTTTCCTGAACGTGATGCAGAAAGTGTGGGCTTTGAAATGGGGGTGATGC
TCAAGGATGAGTTACGGCTTCGTGGCGTATAA

Protein sequence :
MYAPVVRLGTRGSTLALIQAEEVKAAIAAHFPEVRVDVTKIKTSGDIKVDRPLCDIGGKGLFIKEIEEALLANKIDIAVH
SAKDVPGFYSENLDMPCVLKRRSPMDVFISVKYKSLNSLPAGAKIGTSSIRRKVQLLAFRPDLEITPMRGNVDTRIAKVQ
SGECDGIVLAEAGVDRISARAKITEVLHPDVMLGAVGQGAICVQCRKSDEGIVRMLAKLNDHESFTAVLAERSFMKAVNG
SCHTPLAAMARYVDSGLMSMKCMLAHDSRTMVSAERTFPERDAESVGFEMGVMLKDELRLRGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-47 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-47 44