Gene Information

Name : thiC (AM440)
Accession : YP_153743.1
Strain : Anaplasma marginale St. Maries
Genome accession: NC_004842
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 397898 - 399700 bp
Length : 1803 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGCACCCCTGCAATACACACCATACCCACTTGTGTGATACTCATCGCTATTCACAACCCAAAAAAGATGAGCACCCTGC
CATAGGGGTGTTGTGCCTCGATGCAAAAGGGTATATACTCCGCCCGAGTTCTAGGTTTTTTATGGATTATTCCGGAGTAT
ATCCGTCATCCTCTAAAGTGTACGTGCGTGGGAATTTGTATTCTGACGTTAATGTTGGAATGCGTAAGGTTGCCATAAAA
AACGGAACGTCTGAGTTTCTTGTATACGATACAGGCGGGCCCTACACTGACCGCGAGGCCAAGCTGGATATCAAATCTGG
CATACGAAAGTTAAGAAGCACTTGGATCGAAAACAGGCGTGATACTTCCCCCGTGCAAAGAAGTTTTGTTCCCAGCGGGA
GTTCATGCACTAGGTATCAAAAAGCAGCAGAGAATGTCCTGCGGAAAATTGCCGGAGGTAGCCCGGTCACACAGCTGTTT
TATGCCCAAAATGGCATTATAACACCAGAAATGGAATACGTAGCTATTCGCGAAAATGCGCTTCGCATGCAGGTAGGTTC
CTCGGAAACTGGGGCTGCTGCGCACCAGGAGATCACTCCGGAGTTTGTGAGGCAGGAGATAGCAGCAGGAAGGGCAATAA
TCCCGGCAAACATTAATCACCCAGAATCCGAACCCATGGTAATTGGAAGGAATTTTCTGGTCAAAATAAACGCCAACATC
GGGAACTCAGCTGTGCTTTCCGGCATTGAAGAAGAAGTGAAAAAGATGGCGCTCGCCGTCGCGTACGGAGCGGACACAGT
TATGGATTTGTCCACAGGGAGTGACATACACAACATCAGAGAATGGATAATAAGAAACAGCCCAGTGCCCATAGGGACGG
TGCCTATATATCAAGCACTCAACAAGGTAAAAGGGGTTGTTGAGAATCTGAGTTTCGAGGTTTTCAAAGAGACGATAATA
GAACAGGCGGAGCAAGGCGTGGATTATTTTACCATCCATGCCGGCGTGCTGAAAGACTACATCAAGCATGCTCGCGGTCG
GGTTACAGGAATAGTCTCCCGAGGCGGCGCTATTATGGCCCAGTGGTGCTTAGCGCACAACAAGGAGAATTTTTTGTACA
CACACTTTGATGAGATCTGCGAAATCATGGGCAGTTACGATGTTGCCTTTTCCTTGGGAGATGGGCTGAGGCCCGGCTCC
ATAGACGATGCAAACGATGAAGCACAGTTTCTGGAACTGAAAACCCTCGGGGAGCTGGTCAAGGTGGCTTGGCACCATGG
TTGCCAGGTAATGGTTGAAGGCCCCGGACATGTGCCCATGCATCTCATAAAAGAGAACATGGAAAAACAACTGCACCTCT
GTAGTGAGGCACCATTTTACACCCTCGGCCCGCTCACGACTGACATAGCACCGGGTTATGACCATATTACTAGTGCTATA
GGCGCAGCGATGATCGGGTGGTACGGCACTGCAATGCTGTGTTACGTAACTCCAAAAGAGCACTTAGGGCTGCCGAATAT
TGATGACGTAAAAGCGGGGGTGATATCCTATAAAATTGCGGCACACGCCGCTGATCTGGCAAAAGGAAATCCATCCGCCT
ATGCTAGAGATTACGCGCTGAGCCAGGCAAGGTTTGATTTCCGATGGTACGATCAGTTCAATCTCTCGCTAGACCCGCTA
ACTGCAAAGTCGCTACACGATGAATCTCTGCCCGGCAAGGGAGGCAAAACTGCAAATTTCTGTTCCATGTGTGGGCCGAA
ATTTTGCTCAATGAAACTGAGCAAAGAGTTGGTAGACCAATAG

Protein sequence :
MHPCNTHHTHLCDTHRYSQPKKDEHPAIGVLCLDAKGYILRPSSRFFMDYSGVYPSSSKVYVRGNLYSDVNVGMRKVAIK
NGTSEFLVYDTGGPYTDREAKLDIKSGIRKLRSTWIENRRDTSPVQRSFVPSGSSCTRYQKAAENVLRKIAGGSPVTQLF
YAQNGIITPEMEYVAIRENALRMQVGSSETGAAAHQEITPEFVRQEIAAGRAIIPANINHPESEPMVIGRNFLVKINANI
GNSAVLSGIEEEVKKMALAVAYGADTVMDLSTGSDIHNIREWIIRNSPVPIGTVPIYQALNKVKGVVENLSFEVFKETII
EQAEQGVDYFTIHAGVLKDYIKHARGRVTGIVSRGGAIMAQWCLAHNKENFLYTHFDEICEIMGSYDVAFSLGDGLRPGS
IDDANDEAQFLELKTLGELVKVAWHHGCQVMVEGPGHVPMHLIKENMEKQLHLCSEAPFYTLGPLTTDIAPGYDHITSAI
GAAMIGWYGTAMLCYVTPKEHLGLPNIDDVKAGVISYKIAAHAADLAKGNPSAYARDYALSQARFDFRWYDQFNLSLDPL
TAKSLHDESLPGKGGKTANFCSMCGPKFCSMKLSKELVDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 9e-179 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 9e-179 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 8e-167 60