Gene Information

Name : thyA (MGA_0699)
Accession : NP_852828.1
Strain : Mycoplasma gallisepticum R
Genome accession: NC_004829
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 61769 - 62638 bp
Length : 870 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAAACATATTTAGATTTGTTAGAAAAAGTTATGACCAAAGGTGAGGTTAAAAAAGATCGAACTAACACAGGTACGAT
CTCTTATTTTGGCACTCAAAGTCGATATGATTTACGTGAAGGATTTCCATTATTAACAACTAAGAAAATGGCTTGAAAAG
CAATTTGCCATGAATTATTATGATTTCTTAAAGGTGATACGAATATCAAGTACTTGGTTGATCATAATGTGAACATTTGG
AACGAATGACCTTATGAAGCTTTTAAGAAATCAAATGACTTTAAAGGAGAGAGCTTACAAGACTTCGTTGAGAAAATTAA
AACTGATAACCAATTTGCTCAACAATACGGAAAACTAGGCCCTGTGTATGGAAAACAATGACGTGACTTTAATGGCGTTG
ATCAAATTGAGTGAGTTATCAACGAAATTAAAACTAACCCGTTTTCACGTCGTTTAATAGTAAGTGCGTGAAATCCTGGT
GAAATAAAAGAGATGGCCCTACCACCTTGTCATAGTTTTTTCCAGTTCTTTGTTAATGAAAAATATGAAATTTCACTGCA
ACTATACCAAAGAAGTGGGGACCTATTCTTAGGCGTGCCTTTTAATATTGCTTCTTATAGTTTGTTACTTTTAATGGTTG
CTCAAGTAACTGGGTTAAAACCTGCTGAATTTATCCATACAATTGGGGATACCCACATCTATTCAAACCACCTTGAACAA
GTAAAAATTCAACTACAAAGAGAACCTAAAAAACTTCCTAAAGTAACCCTAAACCCTGATATTAAAAATATCTTTGATTT
TAGATTCGAAGATATCAGTTTAGAAAACTATGAACACCATGACCCAATCAAAGGAAAGGTAGCTGTTTAA

Protein sequence :
MKTYLDLLEKVMTKGEVKKDRTNTGTISYFGTQSRYDLREGFPLLTTKKMAWKAICHELLWFLKGDTNIKYLVDHNVNIW
NEWPYEAFKKSNDFKGESLQDFVEKIKTDNQFAQQYGKLGPVYGKQWRDFNGVDQIEWVINEIKTNPFSRRLIVSAWNPG
EIKEMALPPCHSFFQFFVNEKYEISLQLYQRSGDLFLGVPFNIASYSLLLLMVAQVTGLKPAEFIHTIGDTHIYSNHLEQ
VKIQLQREPKKLPKVTLNPDIKNIFDFRFEDISLENYEHHDPIKGKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-68 52
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-55 49