Gene Information

Name : hemC (NE0590)
Accession : NP_840674.1
Strain : Nitrosomonas europaea ATCC 19718
Genome accession: NC_004757
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 643563 - 644489 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCCAGTCCTAAAAAAATTGTTATTGCATCACGCGAGAGCCAGCTCGCTTTGTGGCAGGCGAATTTCATCCGGGGCCG
TCTGCTCGAATTATACCCGCAAACTGATATCACCATACTTGGCATGACGACCAAAGGAGATCAGATTCTGGATGTTTCCC
TGTCGAAAATTGGTGGCAAGGGACTTTTTATCAAGGAGCTCGAGCTGGCGCTGGAAGATGGTCGTGCGGATATCGCCGTG
CATTCCATGAAAGATGTGCCGATGATTGTTCCATCCGGATTCACACTGGCAGCTATTACGGAACGGGAAGATCCGCGTGA
TGCGTTTGTTTCAAATGATTTTTCCAGCTTGGAAGAATTGCCTGCCGGAAGTGTGGTGGGTACCTCCAGCCTGCGACGTG
AATCCCAGTTGCGTGCACGTTTTCCTCATCTGCAGGTGCGGCCGTTGCGTGGCAATGTCCAGACGCGGCTGAGAAAACTG
GATGAGGGAGAATACAGTGCGATCATTCTGGCTGCAGCCGGATTGAAGCGTCTGGAACTGGGGTATCGCATCAGTATGCT
GCTGCCACCCGAACTGAGCCTTCCTGCGGTTGGACAGGGTGCGCTGGGTATCGAATGCCGTGACAATGATCCTGATATGG
TGGAGTGGATGAAGCCATTGCACCACGCTGCAACAGCTTGCTGTGTGGAGGCGGAACGTGCCATGAGCCGTATGCTGGGG
GGCAGCTGTCAAGTGCCTCTGGGTGGCTTTGCCGAGATTTTCGAAGATGTATTGACCCTGCGCGGTTTTGTGGCGACTCC
TGACGGATCGAGAATGATTGCGGATAAATTATGCGGTAAACCGGAATCGGGTGAGCAGGTGGGTCAGCAACTGGCACAAA
ACCTGAAAGCTCATGGTGCGGAGGAAATTCTTGCTGCACTGGCGTGA

Protein sequence :
MSSPKKIVIASRESQLALWQANFIRGRLLELYPQTDITILGMTTKGDQILDVSLSKIGGKGLFIKELELALEDGRADIAV
HSMKDVPMIVPSGFTLAAITEREDPRDAFVSNDFSSLEELPAGSVVGTSSLRRESQLRARFPHLQVRPLRGNVQTRLRKL
DEGEYSAIILAAAGLKRLELGYRISMLLPPELSLPAVGQGALGIECRDNDPDMVEWMKPLHHAATACCVEAERAMSRMLG
GSCQVPLGGFAEIFEDVLTLRGFVATPDGSRMIADKLCGKPESGEQVGQQLAQNLKAHGAEEILAALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-73 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-73 55