Gene Information

Name : thiC (NE0038)
Accession : NP_840139.1
Strain : Nitrosomonas europaea ATCC 19718
Genome accession: NC_004757
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 50259 - 52157 bp
Length : 1899 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAAACGCCCGTTTCTAAGCTGGAAAAATTCACCAATGACAATGCCCGGGTAGATACGGCAGCAGTACAGCCATTGCC
CAATTCACGCAAGATTTATATTCAGGGTTCGCGTGCCGATATCCAGGTGCCAATGCGCGAAATCACCCAATCTGACACTG
CTACCGGACGGGGAGCAGAAAAAAACCCGCCAATCTATGTCTATGATACTTCCGGCCCCTATACTGATCCTGACACTCGC
ATAGATATACGCCATGGCTTGCCTCCTTTGCGCGAAAAATGGATTGATGAACGCGGGGATACCGAAATTCTCACCGGACT
GTCCTCGAGTTACAGTCTGAAAAGGCTGCAGGATCCCGCTCTGACGAAGATGCGCTTCAATCTGATGCGTCCGGTTCGGC
ATGCTAGGAATGGCGCCAATGTCACCCAGATGCACTATGCCAGACGCGGCATCATCACGCCGGAGATGGAATTTATCGCA
CTCCGGGAAAATCAGCGCAGAGAGCGTGTTGCTGATCTGGCAAGTAATGAGTTGTTGAACCGGCAGCATCCCGGACAGAG
TTTCGGTGCAATAATTCAGGAGTGGATCACGCCAGAATTCGTTCGTGATGAAGTAGCATGCGGACGTGCCATCATTCCCG
CCAACATCAATCACCCGGAAACGGAGCCAATGATCATCGGTCGCAATTTTCTGGTCAAGATCAACGCCAATATCGGTAAT
TCCGCACTGGGTTCCAGCATTCAGGATGAGGTGGAGAAAATGACCTGGGCGATCCGCTGGGGAGGAGATACGGTCATGGA
TCTGTCCACCGGAAAAAATATTCATGAGACACGTGAGTGGATTATTCGCAACAGTCCGGTTCCGATTGGAACCGTGCCCA
TTTATCAGGCACTGGAAAAAGTGGATGGCAAAGCGGAAGAGCTGACTTGGGAAATTTTTCGCGATACATTGATCGAGCAG
GCAGAACAGGGAGTGGATTACTTTACGATTCATGCCGGAGTGCGCCTGCCTTTCATTCCGATGACAGCCAAGCGGATGAC
CGGTATCGTTTCGCGTGGAGGTTCCATCATGGCTAAATGGTGCCTGGCGCACCATCAGGAAAGCTTCCTGTATACACATT
TTGAAGATATCTGCGAAATCATGAAGGCCTATGATGTCAGCTTTTCTCTGGGTGACGGATTACGCCCCGGTTCGATTTAC
GACGCTAACGATGAAGCACAGTTTGCCGAGCTGAAAACATTGGGTGAATTAACCGAGATTGCCTGGAAGCATGATGTGCA
GGTGATGATTGAAGGGCCCGGCCATGTGCCTATGCACCTGATCCGGGAAAATATGGATTTGCAGCTCAAATATTGTCACG
AGGCACCTTTTTATACCTTGGGGCCGCTCACGACCGATATTGCTCCCGGTTACGACCACATTACCTCGGCAATCGGTGCT
GCCATGATTGGCTGGTATGGCACGGCCATGCTGTGTTACGTCACGCCTAAAGAGCATCTTGGTTTGCCGGACAAGGATGA
TGTCAAGGATGGAATCATTACCTATAAAATCGCCGCACATGCCGCCGATCTGGCCAAAGGCCATCCTGGTGCGCAAGTTC
GGGATAACGCGCTCTCCAAGGCGCGCTTCGAGTTTCGTTGGAATGATCAGTTCAATCTGAGCCTCGATCCTGACAAAGCC
AGGGAATTTCACGATGAAACATTGCCGCAGGAAGGTGCCAAACTCGCCCATTTCTGCTCGATGTGCGGGCCTAATTTCTG
TTCGATGAAAATTACCCAGGATGTGCGTGACTATGCTGCGCAACAGGGAATCTCCGAGACTGTAGCGTTACAGGAAGGTA
TGGCCAGGAAAGCAAATGAATTCATTGAGAAGGGTGGGGAGCTTTACAGCAAACAATGA

Protein sequence :
MKTPVSKLEKFTNDNARVDTAAVQPLPNSRKIYIQGSRADIQVPMREITQSDTATGRGAEKNPPIYVYDTSGPYTDPDTR
IDIRHGLPPLREKWIDERGDTEILTGLSSSYSLKRLQDPALTKMRFNLMRPVRHARNGANVTQMHYARRGIITPEMEFIA
LRENQRRERVADLASNELLNRQHPGQSFGAIIQEWITPEFVRDEVACGRAIIPANINHPETEPMIIGRNFLVKINANIGN
SALGSSIQDEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQ
AEQGVDYFTIHAGVRLPFIPMTAKRMTGIVSRGGSIMAKWCLAHHQESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIY
DANDEAQFAELKTLGELTEIAWKHDVQVMIEGPGHVPMHLIRENMDLQLKYCHEAPFYTLGPLTTDIAPGYDHITSAIGA
AMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWNDQFNLSLDPDKA
REFHDETLPQEGAKLAHFCSMCGPNFCSMKITQDVRDYAAQQGISETVALQEGMARKANEFIEKGGELYSKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 77
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 77
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 72