Gene Information

Name : hsdR (NE0382)
Accession : NP_840469.1
Strain : Nitrosomonas europaea ATCC 19718
Genome accession: NC_004757
Putative virulence/resistance : Unknown
Product : restriction enzyme type I helicase subunits and related helicases
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 432929 - 436078 bp
Length : 3150 bp
Strand : -
Note : -

DNA sequence :
ATGATCACCGAACAAAAACTGGAAGATACAGCCGTTGGCTGGTTTGCCGAGCTGGGCTGGCCGCATGCCAACGGCCCGGA
GATCGCCCCCGATGGCGACCAGCCCGCCCGCACCGACTACCGCCAAGTGGTGCTGCGAGAACACCTGCTGGCCGCACTGG
CACGCATCAACCCGCACATCCCCGCCGCCGCGCTGGAGCAGGCCGCGCACGAGTTGTTGACGGTGGGCGAGCCGTTGTTG
ATTGCCCGCAATCGCCGTGTGCATCGGCTGCTGCTGTCCGGTATCCCCGTAGAGTTTTCCGTGGGTGATGAAAAGCGCAG
CGATCTGGTCAACCTGATCGACTTTGCCAACCCGCGCAACAACGACTTCCTGCTGGTCAGCCAGTTCACCGTCCGGGCTA
CCCGCCAGCCGCGCCGCCCCGATCTGGTGGCCTTCGTCAACGGCCTGCCGCTGGTGGTGATCGAGCTGAAGAACCCGGCC
AACGAGCAGACCGACATCTGGGATGCCTTGAACCAGATACAGACCTACAAGGAAGAGATTGGCGACCTGTTCAACACCAA
CGTGGCGGTGGTGGTCAGCGATGGCTTCACGGCGCGGTTGGGTTCGCTCACGGCCAATCAGGAGCGCATGCAGCCCTGGC
GGGCGATTGCCAACGAGGACGACCGGCCGCTGCTGGAATTCGAGCTGGAAACGCTGGTGCGTGGCTTCTTCGAGCCGGCG
CTGTTTCTCGACTATGTGCGCCACTTCGTTCTGTTCGAGCAGGATGCCGATCAGATCATCAAGAAGATCGCGGGCTATCA
CCAGTTCCATGCGGTGCGCGAGGCGGTGAAAGCCACGGTGATCGCCGCCAGCAACCCGAACAAAGGTTTGTTGGAAGTGC
AGGAGCCGCGCGCCACCTATGGTAAGGAAGTGCAGCCCGGCAGCCGCAAGGCTGGCGTGGTGTGGCATACGCAAGGCTCG
GGCAAGAGCATCACTATGGCCTGCTACGCGGGCAAGCTGTTGCAGCAGCCGGAGATGAAGAACCCCACCCTGGTGGTGGT
GACCGATCGCAACGATCTGGACGGGCAGTTGTTCGCCACCTTTTGCGCCGCCGAAGACTTGCTCCGTCAAACGCCAGTGC
AGGCCGGCAGCCGCGAGGAGCTGCGCGAAATACTGGCTTCGCGTGAGGCGGGCGGCATCATCTTCACCACGGTGCAGAAG
TTCGCCTTGCTGGACGACGAAGAACAGCACCCGCTGCTGTCGGATCGCAGCAATATCGTGGTGATTTCCGACGAGGCGCA
CCGCAGCCAGTACGGCATGAAAGGGCGACTGGATACCAAGACCGGCAAGTACGTATTTGGCTACGCCAAGCACATGCGCG
ACGCGCTGGCCAACGCCACCTTCATCGGCTTCACCGGCACCCCCATCGCCCTGGAAGACAAAGACACGCGGGCGGTGTTC
GGCGATTACGTCAGCATCTACGACATTCAGGACGCGGTGGACGATGGCGCCACGGTACCGATCTTCTACGAAAGCCGCCT
AGCCAAGCTGGACGTGAACCAGGCCGAGATCGACGCACTCAATGCCCAGGTAGATGAGGTCATCGAGGACGAGGAAGACA
TCACCGCCCGCGAGAAGACCAAGAGCGATTGGGCTGCGCTGACCAAGCTAGTCGGCGCGCAGCCGCGTCTGGAACAGGTG
GCTGCCGACCTGGTGCAGCACTTCGAGACGCGCACAGCCACTCTGGAAGGCAAGGTGATGATCGTGTGCATGAGCCGGGA
CATTTGCGCCGAGCTGTACAACGCCACCGTCGCCCTGCGCCCGGACTGGCACGATGCCGACCCGGAGAAGGGCGCAATCA
AGGTAGTGATGACCGGCTCGGCAGCGGACAAGCCCTTGCTGCAGCCTCACCTGTACAGCCAGCAGGTCAAAAAACTCCTG
GAAAAGCGCTTCAAGGACCCGGCGGACCCGTTGAAGCTGGTGATCGTGCGCGATATGTGGCTGACCGGCTTCGACGCGCC
CTGCTGCCACACGATGTATGTGGACAAGCCCATGAAGGGCCACAACCTGATGCAAGCTATTGCCCGCGTCAACCGGGTAT
TCCGCAACAAGCCCGGCGGGCTGGTGGTGGATTACATCGGCATCGCCAACGAGCTGAAGGCGGCGCTCAAGACCTACACC
GAATCCAAGGGCAAGGGCGACCCGACGCACAACGCGGCCGAAGCTCTGGCAGTCCTGCTGGAGAAGCTGGACATCGTGCG
TGGGCTGATGCACGGCTTCGACTACCGCGGGTTCGAGACCGATGCAATGAAGCTGCTGGTGCCGGTAGCCAACCATATCC
TGGGGCTGAAGGACGGCAAGCAGCGCTTCCTCGATGCCATGCTGGCCGTGAGCAAGGCATTTTCCCTGTGCAGCACGTTG
GATGAAACTGCTGCCTTGCGTACGGAGATTGCCTTCTTCGCCGCCGTCAAGGCCGCCATCGTCAAGTTCACCACGGTGGA
CCGCAAGCGTTCCGACGCAGATAAGAACAGCGCGCTCAAGCAGATTCTGGACAACGCCATCGTCGCTGACGGGGTGGCGG
ATATCTTCGCGCTGGCGGGTCTGGACAAGCCCAACATCGGGCTGTTGTCGGAAGAATTCCTGGAAGATGTGCGACAGATG
AAGAACCGCAACCTGGCGGTAGAGCTTCTGGAAAAACTGCTGAGCGACGAAATCAAGGCGCGCGCACGCAACAACGTGGT
GCAGGAGAAGAAGTACGGCGACCGCCTGCTGGAAACCCTGCGCAAATACCACAACCGGGCGGTGGAGACGGCGCAGATCA
TCGAGGAACTGATCCAGATGGCGAAGGACTTCCAGGCGGCGCTTGAACGCGAAGCCGCGCTGGGGCTGAATCCCGATGAA
ATTGCTTTCTATGATGCACTGGCCAACAACGAAAGCGCCGTGCGGGAGCTGGGAGACGACACCCTCAAGAAAATCGCCGT
CGAGATTACCGAAAAACTGCGCAACAGCACCACGGTGGATTGGCAGGTGCGTGAGAGTGTTCGCGCCAAGCTGCGGATTC
TGGTGCGGCGCACCTTGCAGAAATGGAAGTACCCGCCCGACAAGCAGCTGGAGGCAGTGGAATTGGTGCTACAGCAAGCG
GAAGTGTTGTCGAATTCATGGTCGAAGTGA

Protein sequence :
MITEQKLEDTAVGWFAELGWPHANGPEIAPDGDQPARTDYRQVVLREHLLAALARINPHIPAAALEQAAHELLTVGEPLL
IARNRRVHRLLLSGIPVEFSVGDEKRSDLVNLIDFANPRNNDFLLVSQFTVRATRQPRRPDLVAFVNGLPLVVIELKNPA
NEQTDIWDALNQIQTYKEEIGDLFNTNVAVVVSDGFTARLGSLTANQERMQPWRAIANEDDRPLLEFELETLVRGFFEPA
LFLDYVRHFVLFEQDADQIIKKIAGYHQFHAVREAVKATVIAASNPNKGLLEVQEPRATYGKEVQPGSRKAGVVWHTQGS
GKSITMACYAGKLLQQPEMKNPTLVVVTDRNDLDGQLFATFCAAEDLLRQTPVQAGSREELREILASREAGGIIFTTVQK
FALLDDEEQHPLLSDRSNIVVISDEAHRSQYGMKGRLDTKTGKYVFGYAKHMRDALANATFIGFTGTPIALEDKDTRAVF
GDYVSIYDIQDAVDDGATVPIFYESRLAKLDVNQAEIDALNAQVDEVIEDEEDITAREKTKSDWAALTKLVGAQPRLEQV
AADLVQHFETRTATLEGKVMIVCMSRDICAELYNATVALRPDWHDADPEKGAIKVVMTGSAADKPLLQPHLYSQQVKKLL
EKRFKDPADPLKLVIVRDMWLTGFDAPCCHTMYVDKPMKGHNLMQAIARVNRVFRNKPGGLVVDYIGIANELKAALKTYT
ESKGKGDPTHNAAEALAVLLEKLDIVRGLMHGFDYRGFETDAMKLLVPVANHILGLKDGKQRFLDAMLAVSKAFSLCSTL
DETAALRTEIAFFAAVKAAIVKFTTVDRKRSDADKNSALKQILDNAIVADGVADIFALAGLDKPNIGLLSEEFLEDVRQM
KNRNLAVELLEKLLSDEIKARARNNVVQEKKYGDRLLETLRKYHNRAVETAQIIEELIQMAKDFQAALEREAALGLNPDE
IAFYDALANNESAVRELGDDTLKKIAVEITEKLRNSTTVDWQVRESVRAKLRILVRRTLQKWKYPPDKQLEAVELVLQQA
EVLSNSWSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 65
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 44
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 44
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 43