Gene Information

Name : serS (NE0180)
Accession : NP_840274.1
Strain : Nitrosomonas europaea ATCC 19718
Genome accession: NC_004757
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 218882 - 220195 bp
Length : 1314 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATATCCAACAATTACGCAGCAATCTGCAAAACATCATTACCCGCCTTGCGCAAAGAGGTTACGACTTTCCCGT
AGCGGATTTCGAATCCCTGGAAAGCCAGCGTAAATCTGTCCAAACCCTGACCCAGACATTGCAGGCAAAACGTAATTCAG
CCTCCAAACAAATTGGAATTGCCAGGCAACGGGGTGAAGATGTCAGTCTGATCATGGCCGAAGTGGCCAATATGGGCGAT
GAACTCAAACAGGCAGAAAATCAGCTCGAAGCCGTTCAGACCCGATTGCAACAGCTATTGCTGGAAATTCCCAATCTGCC
ACACGACAGTGTTCCAGCAGGCAAGGATGAAAACGATAATCTGGAAATGCGGCGTTGGGGGACCCCGAAAACGTTTGATT
TTCCGGTACAGGATCATGCCAGCATTGGTGAACACCTCAAGCTGATCGACTTTGAAACAGCCGCAAAGCTGAGTGGTGCG
CGCTTCAGTCTGCTGAAAGGCGGACTGGCGCGACTTCATCGTGCTCTGGCGCAATTCATGCTCGACACACACACACAGGA
AAATGGCTACAACGAAATCTATGTACCTTACCTGGTCAATGCAGACTGTTTGCGGGGTACGGGACAGCTGCCAAAATTTG
AACAGGATCTTTTCGCTGTCCGGTCCGGCGCTCAGGAAGAGGCAGACAACCCGGATAAAACGGGTCCGGCAGGTCTGCAT
CTCATCCCGACTGCCGAAGTCCCTCTTACCAACATTGTACGAAACACGATCGTTCCACTTGAAAATCTCCCGCTTCAATT
TGTCGCGCATACGCCCTGTTTTCGTTCCGAGGCAGGGAGTTACGGCCGAGATACCCGCGGACTGATCCGCCAGCACCAGT
TTGATAAGGTCGAGCTCGTACAAATCACTCATCCGGAAAAATCCCATGAAGCGTTGGAATCACTGGTAGGCCATGCCGAA
AAGATTCTCCAGAAGCTGGAGCTGCCTTACCGTGTCATGCTGCTGTGTACCGGTGACATGGGATTCTCTGCTGCCAAGAC
TTACGATATCGAAGTATGGCTGCCTGCGCAGCAAGCCTACCGGGAAATCTCGTCATGCAGTAATTGTGAAGCATTCCAGG
CGCGGCGCATGCAGGCACGCTTCCGCAAGGGGCAGGAGAAACCTGAGCTGCTGCATACACTCAATGGCTCCGGGCTGGCA
GTCGGGCGGACACTGGTGGCCATTCTGGAAAATTATCAGAATGAAGATGGCAGTATCACCATTCCGGAGATTTTGCGGGC
TTATATGGGTGGCATTGAACGGATCGGCCTATAA

Protein sequence :
MLDIQQLRSNLQNIITRLAQRGYDFPVADFESLESQRKSVQTLTQTLQAKRNSASKQIGIARQRGEDVSLIMAEVANMGD
ELKQAENQLEAVQTRLQQLLLEIPNLPHDSVPAGKDENDNLEMRRWGTPKTFDFPVQDHASIGEHLKLIDFETAAKLSGA
RFSLLKGGLARLHRALAQFMLDTHTQENGYNEIYVPYLVNADCLRGTGQLPKFEQDLFAVRSGAQEEADNPDKTGPAGLH
LIPTAEVPLTNIVRNTIVPLENLPLQFVAHTPCFRSEAGSYGRDTRGLIRQHQFDKVELVQITHPEKSHEALESLVGHAE
KILQKLELPYRVMLLCTGDMGFSAAKTYDIEVWLPAQQAYREISSCSNCEAFQARRMQARFRKGQEKPELLHTLNGSGLA
VGRTLVAILENYQNEDGSITIPEILRAYMGGIERIGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-98 50