Gene Information

Name : murD (NE0989)
Accession : NP_841062.1
Strain : Nitrosomonas europaea ATCC 19718
Genome accession: NC_004757
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1075207 - 1076622 bp
Length : 1416 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAACTATACCGGCAAAAAAATACTGGTTCTGGGCATGGGGAAAACCGGGATTTCCATGGTCAAATGGCTTTCCCGGCT
CGGTGCACAGCTGTCAGTGGCTGATACACGCACCAGCCCGCCCAATCTCGAACTGATAAGCCGGATCGTACCGGGTGAAG
CCATATTCTGCGGCCCGTTGAAGGAAGAATTGTTCCAGGGGATCGATGCAATTGCCATCAGCCCGGGTGTGGCAGTAGCC
GAACCACTGGTACAGGCAGCATTGCAGCAGGGTGTGCCCGTAATCGGTGATATCGAGCTGTTTGCCGTTGCACTCGATCA
GTACGCACCACCGGGTACAAAAATTCTTGCGATCACCGGTTCCAACGGGAAAACCACGGTCACCAGCATGGTCGGTGAAA
TGGTAAAAAATGCCGGATGGGATGTGGAGGTAGCAGGCAATATCGGCCCGGCAGCGCTGGATGCACTGATGCAACGGATG
GATGCAAATAAATGGCCCCATTTGTGGGCGCTGGAACTTTCCAGCTTTCAACTGGAGACCACCAGCAGCCTGCGGCCGGA
TGCAGCAACGGTATTGAACCTGAGCGAAGATCATCTGGACCGGTACGACAGTATCGAAGAATATGCCGCCGCAAAAGCAC
GGATATTTTCCCGCCCGCATAATAATGGTTGCGTGCAGATACTCAATCGTGATGATGCCAGGGTGTATGCCATGGCGGAT
AAAAACAGTAAACAGGTGACTTTTGGTCTATCCGCACCCGTGTCGGACGAAGAATTTGGTTTGCTCCCCGGCGGATCGGA
TGTATGGCTGGCACAAGGCAGTACCCATTTGCTGAAAACCAGTGAGCTTGCCGTCGCGGGACTGCATAACGCCGCCAATG
CGCTGGCTGCACTGGCGTTGTGCCGGGCGGTTGATCTGCCTTTCGAGCCGTTGTTGCATGCTTTGCGTACTTTCAGGGGA
TTGCCGCACCGTATGCAGAAAGTTGCCGAGTTCAATGGCGTAACGTTTTACGACGATTCTAAAAGCACCAACATAGGTTC
AGCTGTTGCCGCACTGAACGGGTTTCGCAAAAACGTGATTCTGATTGCAGGTGGAGATGGCAAAGGGCAGGATTTTTCCC
CTCTGGAACAGCCAGTCAGCAAGCATGTGCGCAGTGTCGTACTGCTGGGAAGGGATGCAGACAAAGTTGCACAGGCCATC
CAGGCCAGCAATGTACCGATACACCGGGTAACCACCATGGATGAGGCGGTACAGGTAAGCTTTCTGCTGGCAGAGCACGG
AGATGTCGTTCTGCTCTCTCCCGCTTGTGCCAGTCTCGATATGTTCAACAATTACATTCACCGCGCTGAGGTTTTCACGG
CTGCCGTCCGCCTGATCGAGCGCAAGTTCGTACTGACAGCACAGACATGTCATTAA

Protein sequence :
MNYTGKKILVLGMGKTGISMVKWLSRLGAQLSVADTRTSPPNLELISRIVPGEAIFCGPLKEELFQGIDAIAISPGVAVA
EPLVQAALQQGVPVIGDIELFAVALDQYAPPGTKILAITGSNGKTTVTSMVGEMVKNAGWDVEVAGNIGPAALDALMQRM
DANKWPHLWALELSSFQLETTSSLRPDAATVLNLSEDHLDRYDSIEEYAAAKARIFSRPHNNGCVQILNRDDARVYAMAD
KNSKQVTFGLSAPVSDEEFGLLPGGSDVWLAQGSTHLLKTSELAVAGLHNAANALAALALCRAVDLPFEPLLHALRTFRG
LPHRMQKVAEFNGVTFYDDSKSTNIGSAVAALNGFRKNVILIAGGDGKGQDFSPLEQPVSKHVRSVVLLGRDADKVAQAI
QASNVPIHRVTTMDEAVQVSFLLAEHGDVVLLSPACASLDMFNNYIHRAEVFTAAVRLIERKFVLTAQTCH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-66 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-66 43