Gene Information

Name : S0719 (S0719)
Accession : NP_836391.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : IS911 orfB
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 713669 - 714295 bp
Length : 627 bp
Strand : -
Note : residues 1 to 208 of 208 are 100.00 pct identical to residues 72 to 279 of 279 from GenPept : >gb|AAL72449.1| (AF386526) InsB [Shigella flexneri 2a]; partial

DNA sequence :
ATGAAAGAGCTGGGGCTGGTCAGCTGTCAGCAGCCGACTCACCGGTATAAACGTGGTGGTCATGAACATGTTGCTATCCC
TAACTACCTTGAAAGGCAGTTCGCCGTGACCGAGCCAAATCAGGTGTGGTGCGGTGATGTGACCTATATCTGGACGGGTA
AGCGCTGGGCGTACCTCGCCGTTGTTCTCGACCTGTTCGCAAGAAAACCAGTGGGCTGGGCCATGTCGTTCTCGCCGGAC
AGCAGGCTCACCATGAAAGCGCTGGAAATGGCATGGGAAACCCGTGGTAAGCCCGGCGGGGTGATGTTCCACAGCGATCA
GGGCAGTCATTATACGAGCAGGCAGTTCCGGCAGTTATTGTGGCGATACCAGATCAGACAGAGTATGAGCCGGCGCGGAA
ACTGCTGGGATAACAGCCCAATGGAACGCTTCTTCAGGAGTCTGAAGAACGAATGGATGCCGGTGGTGGGTTACGTAAGC
TTCAGCGAGGCAGCTCACGCCATAACGGACTATATCGTTGGATATTACAGCGCACTAAGACCGCACGAATATAACGGTGG
GTTACCCCCAAACGAATCGGAAAATCGATACTGGAAAAACTCTAACTCGGTGGCCAGTTTTTGTTGA

Protein sequence :
MKELGLVSCQQPTHRYKRGGHEHVAIPNYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPD
SRLTMKALEMAWETRGKPGGVMFHSDQGSHYTSRQFRQLLWRYQIRQSMSRRGNCWDNSPMERFFRSLKNEWMPVVGYVS
FSEAAHAITDYIVGYYSALRPHEYNGGLPPNESENRYWKNSNSVASFC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
l7094 CAD33743.1 ORF B protein Not tested PAI I 536 Protein 1e-90 90
orfB CAE85178.1 OrfB protein, IS911 Not tested PAI V 536 Protein 1e-90 90
orfB ACX47958.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-78 73
VC1789 NP_231424.1 transposase OrfAB subunit B Not tested VPI-2 Protein 3e-78 73
VPI2_0008c ACA01825.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-78 73
orfB YP_001217329.1 transposase OrfAB subunit B Not tested VPI-2 Protein 3e-78 73
orfB AGK06910.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-78 73
overlap with orfA characteristic of IS3 family members AGK06947.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-78 73
orfB AGK06993.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-78 73
orfB AGK07051.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-78 73
unnamed AAC31485.1 L0006 Not tested LEE Protein 5e-63 63
ECs4537 NP_312564.1 hypothetical protein Not tested LEE Protein 7e-63 63
unnamed CAI43898.1 putative transposase Not tested LEE Protein 1e-62 63
aec65 AAW51748.1 Aec65 Not tested AGI-3 Protein 1e-62 63
unnamed ACU09432.1 IS911 transposase orfB Not tested LEE Protein 4e-63 63
Z5089 NP_290241.1 transposase Not tested LEE Protein 6e-63 63
ECO111_3779 YP_003236114.1 putative IS602 transposase OrfB Not tested LEE Protein 1e-62 63
trp1329B CAB46576.1 IS1329 transposase B Not tested HPI Protein 2e-33 46
tnpB CAB61574.1 transposase B Not tested HPI Protein 3e-34 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S0719 NP_836391.1 IS911 orfB VFG1484 Protein 7e-91 90
S0719 NP_836391.1 IS911 orfB VFG1122 Protein 8e-79 73
S0719 NP_836391.1 IS911 orfB VFG0785 Protein 2e-63 63