Gene Information

Name : kdpA (S0609)
Accession : NP_836305.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : potassium-transporting ATPase subunit A
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2060
EC number : 3.6.3.12
Position : 620828 - 622501 bp
Length : 1674 bp
Strand : +
Note : catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

DNA sequence :
ATGGCTGCGCAAGGGTTCTTACTGATTGCCACGTTTTTACTGGTATTAATGGTGCTGGCGCGTCCTTTAGGCAGCGGGCT
GGCGCGGCTGATTAATGACATTCCTCTTCCAGGTACAGCGGGCGTTGAACGTATACTCTTTCGTTTACCTGGCGTCTCTG
ACCATGAGATGAACTGGAAGCAATATCTTTGTGCCATTCTCGGCCTGAACATGCTGGGGCTGGCGGTGCTGTTTTTTATG
TTGCTCGGTCAGCACTATCTGCCGCTTAATCCACAGCAGTTGCCGGGGCTGTCGTGGGATCTGGCGCTGAATACCGCCGT
CAGCTTTGTCACGAATACCAACTGGCAATCTTATAGCGGTGAAACCACGTTGAGCTATTTCAGCCAGATGGCAGGCTTAA
CGGTACAAAACTTTCTTTCTGCCGCCAGCGGGATTGCGGTGATTTTTGCCTTCATCCGTGCGTTTACTCGCCAGAGCATG
AGCACACTCGGGAATGCCTGGGTCGATCTGCTACGCATCACGTTATGGGTGCTAGTCCCTGTGGCGTTGTTGATCGCACT
GTTTTTTATTCAACAAGGTGCGCAGCAAAACTTTCTGCCCTATCAGGCAGTGAATACCGTTGAAGGAGCGCAACAGCTGT
TACCCATGGGACCAGTAGCTTCTCAGGAAGCGATCAAGATGCTCGGTACTAACGGCGGTGGCTTCTTTAATGCCAACTCG
TCGCATCCGTTTGAAAACCCAACCGCACTGACCAACTTCGTGCAGATGCTGGCGATCTTCTTGATCCCAACAGCGCTGTG
CTTTGCCTTTGGTGAAGTGACGGGCGATCGCCGCCAGGGGCGCATGTTGCTGTGGGCGATGTCAGTGATTTTTGTCATCT
GCGTAGGCGTGGTTATGTGGGCAGAAGTTCAGGGTAATCCTCATCTGCTGGCGCTCGGCGCAGACAGCAGCATCAATATG
GAAGGTAAAGAGAGCCGTTTCGGCGTGCTGGTCAGTAGCCTGTTTGCGGTCGTGACTACGGCGGCGTCCTGTGGCGCGGT
GATTGCGATGCATGATTCGTTTACCGCTCTCGGCGGCATGGTGCCGATGTGGCTAATGCAAATTGGTGAAGTGGTGTTCG
GCGGTGTCGGTTCTGGTCTTTACGGCATGATGCTGTTTGTCCTGCTGGCGGTGTTTATTGCCGGGCTGATGATTGGTCGT
ACACCGGAATATCTGGGTAAAAAAATAGACGTACGCGAGATGAAACTGACTGCACTGGCGATTCTGGTTACTCCAACACT
GGTACTGATGGGCGCGGCGTTGGCGATGATGACCGACGCCGGACGTAGCGCCATGCTTAACCCTAGCCCGCATGGTTTTA
GCGAAGTGCTGTACGCCGTGTCGTCCGCCGCTAACAACAACGGCAGCGCCTTTGCCGGATTAAGCGCCAACTCTCCGTTC
TGGAACTGTTTACTGGCGTTCTGCATGTTTGTCGGTCGCTTCGGGGTGATTATCCCGGTGATGGCAATTGCCGGTTCGCT
GGTGAGTAAAAAGAGCCAACCCGCCAGCTCCGGCACGCTGCCAACGCACGGCCCGCTGTTTGTTGGCCTGTTAATCGGCA
CCGTGTTGCTGGTTGGCGCACTGACCTTTATCCCTGCCCTGGCGCTTGGTCCGGTGGCGGAATATCTCTCCTGA

Protein sequence :
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFAFIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGAQQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPSPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kdpA NP_814333.1 potassium-transporting ATPase subunit A Not tested Not named Protein 2e-83 50
ef0087 AAM75290.1 EF0087 Not tested Not named Protein 1e-83 50
SAR0070 YP_039538.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 6e-70 45
truncated-kdpA NP_370596.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 6e-70 45
kdpA NP_373308.2 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 6e-70 45
kdpA YP_190030.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 6e-70 45
kdpA YP_251948.1 potassium-transporting ATPase subunit A Not tested SCCmec Protein 3e-71 45
unnamed BAB43902.1 potassium-transporting ATPase(A chain) Not tested Type-II SCCmec Protein 5e-70 45