Gene Information

Name : hpcR (S4655)
Accession : NP_839767.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : regulator of the 4HPA-hydroxylase operon
Function : -
COG functional category : K : Transcription
COG ID : COG1846
EC number : -
Position : 4549533 - 4549979 bp
Length : 447 bp
Strand : +
Note : residues 1 to 148 of 148 are 100.00 pct identical to residues 1 to 148 of 148 from GenPept : >emb|CAA86039.1| (Z37980) regulator of the meta operon of 3,4dhpa metabolic pathway [Escherichia coli]

DNA sequence :
ATGCACGACTCACTAACCATTGCGTTGCTCCAGGCGCGAGAAGCGGCGATGAGTTATTTTCGCCCAATCGTTAAACGGCA
TAATTTGACTGAGCAACAGTGGCGCATCGTGCGTATTCTGGCGGAAAGCCCATCAATGGATTTTCACGATCTGGCGTATC
GCGCCTGCATTTTGCGCCCAAGCCTGACCGGGATCCTCACGCGGATGGAACGCGACGGTTTAGTGTTGCGATTAAAGCCG
ATCAATGATCAGCGGAAGCTCTATATCTCGCTGACCAAAGAGGGGCAGGCGCTGTATAACCGCGCTCAGACACAGATTGA
AGAAGCCTATCGGCAGATTGAAGCTCAGTTTACTGCCGAGAAAATGCAACAGTTAACCCATCTGTTAGAGGAATTTATTG
CTCTGGGCAATTCCCGACAAGAAGACATCCCGGGCGATAATGAATAA

Protein sequence :
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKP
INDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpcR AAO17176.1 HpcR Not tested tcd island Protein 7e-48 66

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpcR NP_839767.1 regulator of the 4HPA-hydroxylase operon BAC0505 Protein 6e-34 58