Gene Information

Name : fimC (S4463)
Accession : NP_839600.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : periplasmic chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 4371286 - 4372011 bp
Length : 726 bp
Strand : -
Note : residues 1 to 241 of 241 are 99.17 pct identical to residues 1 to 241 of 241 from Escherichia coli K-12 : B4316; required for type 1 fimbriae

DNA sequence : 
GTGAGTAATAAAAACGTCAATGTAAGGAAATCGCAGGAAATAACATTCTGCTTGCTGGCAGGTATCCTGATGTTCATGGC
AATGATGGTTGCCGGACGCGCTGAAGCAGGAGTGGCCTTAGGTGCGACTCGCGTAATTTATCCGGCAGGGCAAAAACAAG
TGCAACTTGCCGTGACAAATAATGATGAAAATAGTACCTATTTAATTCAATCATGGGTGGAAAATGCCGATGGTGTAAAG
GATGGTCGTTTTATCGTGACGCCTCCTCTGTTTGCGATGAAGGGAAAAAAAGAGAATACCTTACGTATTCTTGATGCAAC
AAATAACCAATTGCCACAGGACCGGGAAAGTTTATTCTGGATGAACGTTAAAGCGATTCCGTCAATGGATAAATCAAAAT
TGACTGAGAATATGCTACAGCTCGCAATTATCAGCCGCATTAAACTGTACTATCGCCCGGCTAAATTAGCGTTGCCACCC
GATCAGGCCGCAGAAAAATTAAGATTTCGTCGTAGCGCGAATTCTCTGACGCTGATTAACCCGACACCCTATTACCTGAC
GGTAACAGAGTTGAATGCCGGAACCCGGGTTCTTGAAAATGCATTGGTGCCTCCAATGGGCGAAAGCACGGTTAAATTGC
CTTCTGATGCAGGAAGCAATATTACTTACCGAACAATAAATGATTATGGCGCACTTACCCCCAAAATGACGGGCGTAATG
GAATAA

Protein sequence : 
MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATRVIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVK
DGRFIVTPPLFAMKGKKENTLRILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENMLQLAIISRIKLYYRPAKLALPP
DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAGSNITYRTINDYGALTPKMTGVM
E

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2C AFH78430.1 putative fimbrial chaperone protein Virulence KpGI-5 Protein 1e-83 84
sfaE CAC16952.2 SfaE protein Virulence PAI III 536 Protein 2e-70 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fimC NP_839600.1 periplasmic chaperone VFG0875 Protein 1e-109 99
fimC NP_839600.1 periplasmic chaperone VFG0911 Protein 6e-71 66
fimC NP_839600.1 periplasmic chaperone VFG1644 Protein 9e-71 66
fimC NP_839600.1 periplasmic chaperone VFG0445 Protein 2e-53 48