Gene Information

Name : S4440 (S4440)
Accession : NP_839580.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : ISSfl3 orfD
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG3436
EC number : -
Position : 4350527 - 4351489 bp
Length : 963 bp
Strand : +
Note : residues 1 to 320 of 320 are 99.68 pct identical to residues 214 to 533 of 533 from GenPept : >gb|AAL72472.1| (AF386526) hypothetical protein [Shigella flexneri 2a]

DNA sequence :
ATGGAACATATCCCTTTATATCGCCAGTCAGAAATATACGCGCGACAGGGCGTGGAGCTGAGCCGTAATACCATGGTGCG
CTGGGTATCAGAAATGGCAGACAAACTCCGTCCTCTGTATATAGCGCTGAATGACTATGTTCTGGAGGCAGGAAAGGTGC
ACGCAGATGACACTCCGGTGAAAGTACTGGCCCCGGGGAACGGAAAGACGAAAACGGGTCGTCTGTGGGTATACGTCAGG
GATGATCGTAATGCGGGTTCATCCCTGCCGGCAGCCGTCTGGTTCGCGTATTCGGCAGATCGCAAAGGAGAACATCCGCA
GCTCCACCTGGCAAAGTATCAGGGCGTACTGCAGGCTGATGCCTATGCAGGTTATAACGTACTGTACGAAACGGGCCGGG
TGAAGGAAGCCGGGTGCCTGGCCCACGCCCGCCGAAAAATCCATGACGAGGATGTGCGCCGTCCGACAGAAATGACTCAG
GAAGCGCTCAGACGGATAGCAGAGTTATACGACATAGAAGCGGAGATACGTGGCAGTCCGGCAGAGGAACGGCTTGCAGT
CAGAAAAGCCAGAAGCGTCCAGTTGATGCAGTCGTTGTACGACTGGATACAGTTGCAGAGGAAAACGCTGTCGAAACATG
CGGAGATGGCGAAGGCGTTCGACTATATCCTGAATCACTGGAATGCGCTGAACGAGTTCTGTCGTGACGGCTGGGTGGAA
ATAGACAACAACATCGGTGAAAACGCGTTACGATCGGTGGCGGTTGGAAGAAAAAATTATCTCTTTTTCGGCTCAGACAA
GGGAGGAGAAAGTGCGGCGATCATCTACAGTCTGCTGGTCACCTGCAAACAGAACGAAGTGGAGCCGGAGGACTGGTTGC
GCGAAGTGATCGAGAAGCTCAATGACTGGCCGTCGAACCAAGTGCATAAACTGCTGCCCTGGAACTTCTCGTCTGTAAAA
TAA

Protein sequence :
MEHIPLYRQSEIYARQGVELSRNTMVRWVSEMADKLRPLYIALNDYVLEAGKVHADDTPVKVLAPGNGKTKTGRLWVYVR
DDRNAGSSLPAAVWFAYSADRKGEHPQLHLAKYQGVLQADAYAGYNVLYETGRVKEAGCLAHARRKIHDEDVRRPTEMTQ
EALRRIAELYDIEAEIRGSPAEERLAVRKARSVQLMQSLYDWIQLQRKTLSKHAEMAKAFDYILNHWNALNEFCRDGWVE
IDNNIGENALRSVAVGRKNYLFFGSDKGGESAAIIYSLLVTCKQNEVEPEDWLREVIEKLNDWPSNQVHKLLPWNFSSVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SF2972 NP_708746.1 hypothetical protein Not tested SHI-1 Protein 7e-96 66
unnamed AAK00463.1 unknown Not tested SHI-1 Protein 2e-98 66
c3563 NP_755438.1 hypothetical protein Not tested PAI I CFT073 Protein 1e-95 65
unnamed AAL67373.1 unknown Not tested PAI II CFT073 Protein 8e-55 57
unnamed AAL67335.1 L0015-like protein Not tested PAI II CFT073 Protein 1e-56 56
Z4314 NP_289540.2 hypothetical protein Not tested OI-122 Protein 4e-56 51
RS12 AAP82957.1 transposase Not tested PAPI-2 Protein 4e-47 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S4440 NP_839580.1 ISSfl3 orfD VFG0634 Protein 3e-96 66
S4440 NP_839580.1 ISSfl3 orfD VFG1700 Protein 4e-96 65