Gene Information

Name : S4250 (S4250)
Accession : NP_839400.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 4166011 - 4166571 bp
Length : 561 bp
Strand : +
Note : residues 1 to 177 of 186 are 47.54 pct identical to residues 59 to 239 of 241 from GenPept : >gb|AAD26595.1| (AF012835) chaperone protein AafD [Escherichia coli]

DNA sequence :
ATGCTTGTGCAGAGTAAAGTCTTTGAAGAAGATAAAGTAACTGCAGCGCCCTTTATTGTCACTCCGCCACTGTTCAGGCT
TAATCCAGGCCAGCAAAATAAAATGTGGGTTGTGCAGACTGCGCCAGCTTTACAAGACAGGGAAAAATTACACTGGCTAT
GCGCCACCGGCATTACGCCTAAAAAGAGTGATGTTTGGGCCGAGAAAGATAAAGAAAAAATTGCTGAAAATGTGAACCTG
AACATCCAGGTTAACGTACATACCTGCATAAAACTTATTACCAGGCCATCTGGTATTGAAGGCAAGATGGTTAATGCGAG
TGAGAAGTTATCGTGGAAAAAGCAGGGTGATAAAATTGTCGCGGTCAATCAGTCGCCGTTCTACATCAACCTTTCTTCTT
TACAGGTTGGCGGTAGCAAGATTGAGAAACTAGATTATATTGCGCCGTTTTCGCAACATGAGTTTGTTATGCCAAAAACT
AGCGGCCAGGATATTAAATGGTCTGTGATTACTGATGAAGGTGGTGAGAGTCGTTTGTTTATATCTCATTTGCAATCATA
A

Protein sequence :
MLVQSKVFEEDKVTAAPFIVTPPLFRLNPGQQNKMWVVQTAPALQDREKLHWLCATGITPKKSDVWAEKDKEKIAENVNL
NIQVNVHTCIKLITRPSGIEGKMVNASEKLSWKKQGDKIVAVNQSPFYINLSSLQVGGSKIEKLDYIAPFSQHEFVMPKT
SGQDIKWSVITDEGGESRLFISHLQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
afaB AAK16197.1 AfaB Virulence PAI-I AL862 Protein 1e-39 42
afaB ADD91742.1 putative AfaB-VIII periplasmic chaperone Not tested PAI-I AL862 Protein 1e-39 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S4250 NP_839400.1 chaperone VFG0852 Protein 7e-40 47
S4250 NP_839400.1 chaperone VFG0858 Protein 2e-41 45
S4250 NP_839400.1 chaperone VFG0850 Protein 2e-41 43