Gene Information

Name : arsR (S4232)
Accession : NP_839383.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : DNA-binding transcriptional repressor ArsR
Function : -
COG functional category : K : Transcription
COG ID : COG0640
EC number : -
Position : 4146620 - 4146964 bp
Length : 345 bp
Strand : +
Note : regulates the expression of of the arsRBC involved in resistance to arsenic

DNA sequence :
CTGTTACCCATCCAATTGTTCAAAATTCTTGCTGATGAAACCCGTCTGGGCATCGTTTTACTGCTTAGCGAACTGGGAGA
GTTATGCGTCTGCGATCTCTGCACTGCCCTCGATCAGTCGCAGCCCAAGATATCCCGCCATCTGGCATTGCTGCGTGAAA
GCGGGCTATTGCTGGACCGCAAGCAAGGTAAGTGGGTTCATTACCGCTTATCGCCGCATATTCCAGCATGGGCGGCGAAA
ATTATTGATGAAGCCTGGCGATGTGAACAGGAAAAGATTCAGGCAATTGTCCGCAACCTGGCCAGACAAAACTGTTCCGG
AGACAGTAAGAACATTTGCAGTTAA

Protein sequence :
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAK
IIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsR2 YP_001007630.1 DNA-binding transcriptional repressor ArsR Not tested YAPI Protein 1e-38 73
arsR AFC76435.1 ArsR Not tested AbaR5 Protein 3e-19 50
arsR CAJ77018.1 arsenite inducible repressor Not tested AbaR1 Protein 2e-19 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsR NP_839383.1 DNA-binding transcriptional repressor ArsR BAC0594 Protein 6e-48 99
arsR NP_839383.1 DNA-binding transcriptional repressor ArsR BAC0589 Protein 1e-39 77
arsR NP_839383.1 DNA-binding transcriptional repressor ArsR BAC0591 Protein 6e-40 76
arsR NP_839383.1 DNA-binding transcriptional repressor ArsR BAC0588 Protein 5e-30 71