Gene Information

Name : shiA (S4834)
Accession : NP_839237.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3965821 - 3966864 bp
Length : 1044 bp
Strand : -
Note : residues 1 to 347 of 347 are 100.00 pct identical to residues 1 to 347 of 347 from NRprotein_Feb03 : >ref|NP_709438.1| orf, conserved hypothetical protein [Shigella flexneri 2a str. 301] pir||T44464 hypothetical protein shiA [imported] - Shigella flexneri

DNA sequence : 
ATGAACGATAGATTATGCTTTGAAGTGCACGATAACAAGGGTTATTTCGTATTTCCGGATACCTGGTTTGGCCCATTGCT
GGGGGAGTTTGAAGAAGTGCTTGATGCATACGACGCTGATGAAATCAGCGAGACGAGTTACATCAACAAACTCCGACGCC
TTGCTCAACGGGAGCCGGACTTTATTGATATACACGCTCATCTGGCATATGCATTTCTGGAACAGAATGCCCCGCGTAAG
GCACTGAACGCCGCTCTTAAAGGACTGGCGGCAGGTAATCGTATCATCCCGGAAAGTTTCTGTGGTGAAATAATCTGGAT
GCATCCCGAAAACCGGCCTTATCTGCGCGCGCTTTATGCAGCAATTCTCGCAAATGTGCACTTACAGCGCCATCAGGATG
CGGTTATGCTCACTGATAAAATACTGGCATACAATCCTGAAGATAATCAGGGGGCTCGCTGGTTGTTGGGTTCAGAGCTG
TTACGCACCGGCGATCATGAGCGAGCCTTCAGTGTACTGAAAGAGCATGCTGATGAATTTTCACCTTACTGGTATGAACT
CGGTCTCCTGCATTTTCTGAACGGGGAACATGTTAAGGCCGCCACAGCTTTTCGCCATGGCTTTGCCACAAACACTTACA
TCGCAGAAATGCTGTGCGGAAATCTGCATCCATTTCCACTTGCTGTGTGGCATGACTTCTCCGGCTCTCTGGATACGGCA
GAAGATTACTATGCAACATACTCACCATTATGGGGACAATATCCGGAAGCATTGCTGTTTGTAAACTGGCTCTATAACCA
TTCCTCCGTGCTGCATGAACGATCAGAAATCATTAAATGCGCCGAAATGCTGATTCAGGAAGATGATTTCGAAATATGCG
AAAGTATTTTAAGACAGCAGGAGCACCTGTGGAAAAGAATTGACAAGACACTTTCTGAGGAAATTGTACAGAAATGCAGA
AATATGAACGGTGAATATATCTGGCCCTGGATATTGCCCTTTTCCGCAGCAGGGATGAAACATTCAAGCATCCAGTATCA
GTAG

Protein sequence : 
MNDRLCFEVHDNKGYFVFPDTWFGPLLGEFEEVLDAYDADEISETSYINKLRRLAQREPDFIDIHAHLAYAFLEQNAPRK
ALNAALKGLAAGNRIIPESFCGEIIWMHPENRPYLRALYAAILANVHLQRHQDAVMLTDKILAYNPEDNQGARWLLGSEL
LRTGDHERAFSVLKEHADEFSPYWYELGLLHFLNGEHVKAATAFRHGFATNTYIAEMLCGNLHPFPLAVWHDFSGSLDTA
EDYYATYSPLWGQYPEALLFVNWLYNHSSVLHERSEIIKCAEMLIQEDDFEICESILRQQEHLWKRIDKTLSEEIVQKCR
NMNGEYIWPWILPFSAAGMKHSSIQYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
shiA AAD44731.1 ShiA Virulence SHI-2 Protein 8e-155 100
shiA NP_839237.1 hypothetical protein Virulence SHI-2 Protein 1e-154 100
shiA NP_709438.1 hypothetical protein Virulence SHI-2 Protein 1e-154 100
aec34 AAW51717.1 Aec34 Not tested AGI-3 Protein 8e-151 97
shiA AFX83956.1 ShiA family protein Not tested SE-PAI Protein 1e-137 88
c3557 NP_755432.1 ShiA-like protein Not tested PAI I CFT073 Protein 6e-134 84
ECUMN_3323 YP_002414005.1 SHI-2 pathogenicity island protein Virulence Not named Protein 3e-135 84

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
shiA NP_839237.1 hypothetical protein VFG0599 Protein 5e-155 100
shiA NP_839237.1 hypothetical protein VFG1694 Protein 3e-134 84