Gene Information

Name : iucD (S4053)
Accession : NP_839220.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : lysine:N6-hydroxylase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : -
Position : 3948660 - 3949997 bp
Length : 1338 bp
Strand : -
Note : residues 1 to 445 of 445 are 100.00 pct identical to residues 1 to 445 of 445 from GenPept : >gb|AAD44749.1|AF141323_20 (AF141323) IucD [Shigella flexneri]

DNA sequence :
ATGAAAAAAAGTGTCGATTTTATTGGTGTCGGGACAGGGCCATTTAATCTCAGCATTGCTGCATTGTCACATCAGATCGA
AGAACTGAACTGTCTCTTCTTTGACGAACATCCTCATTTTTCCTGGCATCCGGGTATGCTGGTACCGGATTGTCATATGC
AGACCGTCTTTCTGAAAGATCTGGTCAGTGCAGTTGCACCTACAAATCCCTACAGCTTTGTTAACTATCTGGTGAAGCAC
AAAAAGTTCTATCGCTTCCTTACAAGCAGGCTACGTACAGTATCCCGTGAAGAGTTTTCTGACTATCTCCGCTGGGCTGC
TGAAGATATGAATAACCTGTATTTCAGTCATACCGTTGAAAATATTGATTTCGACAAAAAAAGTCGATTGTTTCTGGTTC
AGACCAGTCGGGGAGAATATTTTGCCCACAATATCTGCCTTGGTACAGGAAAACAACCTTATTTACCACCCTGTGTGAAG
CATGTGACACAATCCTGTTTCCATGCCAGTGAAATGAATCTTCGTCGGCCGGACCTGAGTGGAAAACGGATAACCGTGGT
TGGTGGAGGACAGAGTGGTGCAGACCTGTTCCTTAATGCATTACGCGGGGAATGGGGAGAAGCGGCGGAAATAAACTGGG
TCTCACGGCGTAATAATTTTAACGCACTGGATGAGGCTGCTTTTGCTGATGAGTATTTTACACCTGAATATATTTCAGGC
TTCTCCGGACTGAAGGAAGATATTCGCCATCAGTTACTGGATGAGCAGAAAATGACATCGGATGGCATCACTGCCGATTC
TTTACTGACCATTTATCGTGAGTTGTACCACCGTTTTGAAGTTCTGAGAAAACCAAGAAATATCCGTCTGCTACCCAGTC
GCTCGGTAACAACTCTGGAAAGTAGTGGTCCGGGCTGGAGGTTATTGATGGAACATCATCTGGATCAGGGCAGAGAGAGC
CTGGAAAGTGATGTGGTGATTTTCGCCACAGGTTACCGTTCTGCATTGCCACAAATACTTCCCTCACTGATGCCCTTGAT
CACCATGCACGATAAGAACACCTTTAAAGTGCGTGATGACTTCACTCTGGAATGGAGTGGCCCGAAAGAAAATAACATCT
TTGCGGTCAACGCCAGCATGCAAACTCATGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGATCTGCACGTATT
CTTAATCGCGTACTGGGGCGTGATTTATTCGATCTCAGTATGCCGCCCGCACTGATTCAGTGGCGCAGCGGCAGCCGGAA
AAAACCACAGCCGGAGGCTGCTTCTTTAACTCACTATACAGCAAATATTCAGGAATAA

Protein sequence :
MKKSVDFIGVGTGPFNLSIAALSHQIEELNCLFFDEHPHFSWHPGMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKH
KKFYRFLTSRLRTVSREEFSDYLRWAAEDMNNLYFSHTVENIDFDKKSRLFLVQTSRGEYFAHNICLGTGKQPYLPPCVK
HVTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRNNFNALDEAAFADEYFTPEYISG
FSGLKEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVLRKPRNIRLLPSRSVTTLESSGPGWRLLMEHHLDQGRES
LESDVVIFATGYRSALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFAVNASMQTHGIAEPQLSLMAWRSARI
LNRVLGRDLFDLSMPPALIQWRSGSRKKPQPEAASLTHYTANIQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD AAD44749.1 IucD Virulence SHI-2 Protein 0.0 100
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 100
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 100
iucD AAK71634.1 IucD Virulence SHI-3 Protein 0.0 99
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucD NP_839220.1 lysine:N6-hydroxylase VFG0618 Protein 0.0 100
iucD NP_839220.1 lysine:N6-hydroxylase VFG0937 Protein 0.0 99
iucD NP_839220.1 lysine:N6-hydroxylase VFG1084 Protein 0.0 99