Gene Information

Name : iutA (S4052)
Accession : NP_839219.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : ferric siderophore receptor
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1629
EC number : -
Position : 3946459 - 3948654 bp
Length : 2196 bp
Strand : -
Note : residues 1 to 731 of 731 are 97.40 pct identical to residues 2 to 732 of 732 from GenPept : >gb|AAD44750.1|AF141323_21 (AF141323) IutA [Shigella flexneri]

DNA sequence :
ATGCGCAAAAAGTATATGCCCCGGGCTCTTGGTCCGCTGCTTCTTGTCGTGCTGTCACCAGCTGTCGCCCAGCAAAACGA
TGATAATGAGATCATAGTGTCTGCCAGCCGCAGCAATCGAACTGTAGCGGAGATGGCGCAAACCACCTGGGTTATCGAAA
ATGCCGAACTGGAGCAGCAGATTCAGGGCGGTAAAGAGCTGAAAGACGCACTGGCTCAGTTAATCCCCGGCCTTGATGTC
AGCAGCCAGAGTCGAACCAACTACGGTATGAACATGCGTGGCCGCCCGCTGGTTGTCCTGATTGACGGTGTGCGCCTCAA
CTCTTCACGTTCCGACAGCCGACAACTGGACTCTGTCGATCCTTTTAATATCGACCATATTGAAGTGATCTCCGGCGCGA
CGGCCCTGTACGGTGGCGGGAGTACCGGAGGGTTGATCAACATCGTGACCAAAAAAGGTCAGCCGGAAACCATGATGGAG
TTTGAGGCTGGCACAAAAAGTGGCTTTAACAGCAGTAAAGATCACGATGAGCGCATTGCCGGTGCTGTCTCCGGCGGAAA
TGACCATATCTCCGGACGTCTTTCCGTGGCATATCAGAAATTTGGCGGCTGGTTTGACGGTAACGGCGATGCCACCCTGC
TTGATAACACCCAGACCGGCCTGCAGCACTCCAATCGGCTGGACATCATGGGAACCGGTACGCTGAACATCGATGAATCC
CGGCAGCTTCAACTGATAACGCAGTACTATAAAAGTCAGGGAGACGACAATTACGGGCTTAATCTCGGGAAAGGCTTTTC
CGCCATCAGCGGGAGCAGCACACCATACGTCAGTAAGGGGCTGAATTCTGACCGCATTCCCGGCACTGAGCGGCATTTGA
TCAGCCTGCAGTACTCTGACAGTGATTTCCTGGGACAGGAACTGGTCGGTCAGGTTTACTACCGCGATGAGTCGTTGCGG
TACTACCCGTTCCCGACGGTAAATGCGAATAAACAGGCGACGGCTTTCTCCTCGTCACAGCAGGATACCGACCAGTACGG
CATGAAACTGACTCTGAACAGCCAACTGATGGACGGCTGGCAAATCACCTGGGGGCTGGATGCTGAGCATGAGCGCTTTA
CCTCCAACCAGATGTTCTTCGATCTGGCTCAGGCAAGTGCTTCCGGAGGGCTGAACAACCATAAGATTTACACCACCGGG
CGCTATCCGTCATATGACATCACCAATCTGGCGGCCTTCCTGCAATCCAGCTATGACATTAATGATATTTTTACCGTTAG
CGGTGGCGTACGCTATCAGTATACTGAGAACAGGGTAGATGATTTCATCGACTACACGCAGCAACAGAAGATTGCTACCG
GGAAGGCGATATCTGCCGACGCCATTCCTGGTGGTTCGGTAGATTACGATAACTTTCTGTTCAATGCTGGTCTGCTGATG
CACATCACCGAACGTCAGCAGGCATGGTTCAATTTTTCCCAGGGGGTGGCATTGCCGGATCCGGGGAAATATTATGGTCG
CGGCATCTATGGTGCAGCAGTGAACGGCCATCTTCCCCTGACAAAGAGCGTGAACGTCAGCGACAGTAAGCTGGAAGGCG
TGAAAGTCGATTCTTATGAACTGGGCTGGCGCTTTATCGGTGACAACCTGCGGACTCAAATCGCGGCATATTACTCGCTT
TCCAATAAGAGCGTGGAAAGGAATAAAGATCTGACCATCAGTGTGAAGGACGACAGGCGCCGTATTTACGGCGTGGAAGG
TGCGGTGGACTACCTGATCCCGGATACTGACTGGAGTACCGGTGTGAACTTCAATGTGCTGAAAACCGAGTCGAAAGTGA
ACGGTCAATGGCAAAAATATGACGTGAAGGAATCAAGTCCATCGAAAGCGACAGCTTACATTAACTGGGCGCCGGAACCG
TGGAGTCTGCGTGTACAGAGCACCACTTCTTTCGACGTAAGCGATGCAGAGGGTAACGATATTAATGGTTACACTACCGT
CGATTTTATCAGTAGTTGGCAGCTTCCGGTGGGAACACTCAGCTTCAGCGTTGAGAACCTCTTCGACCGTGACTATACCA
CTGTCTGGGGACAGCGTGCACCTCTGTACTACAGCCCGGGTTACGGCCCTGCTTCACTGTACGACTACAAAGGCCGGGGC
CGAACCTTTGGTCTGAACTACTCAGTGCTGTTCTGA

Protein sequence :
MRKKYMPRALGPLLLVVLSPAVAQQNDDNEIIVSASRSNRTVAEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDV
SSQSRTNYGMNMRGRPLVVLIDGVRLNSSRSDSRQLDSVDPFNIDHIEVISGATALYGGGSTGGLINIVTKKGQPETMME
FEAGTKSGFNSSKDHDERIAGAVSGGNDHISGRLSVAYQKFGGWFDGNGDATLLDNTQTGLQHSNRLDIMGTGTLNIDES
RQLQLITQYYKSQGDDNYGLNLGKGFSAISGSSTPYVSKGLNSDRIPGTERHLISLQYSDSDFLGQELVGQVYYRDESLR
YYPFPTVNANKQATAFSSSQQDTDQYGMKLTLNSQLMDGWQITWGLDAEHERFTSNQMFFDLAQASASGGLNNHKIYTTG
RYPSYDITNLAAFLQSSYDINDIFTVSGGVRYQYTENRVDDFIDYTQQQKIATGKAISADAIPGGSVDYDNFLFNAGLLM
HITERQQAWFNFSQGVALPDPGKYYGRGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFIGDNLRTQIAAYYSL
SNKSVERNKDLTISVKDDRRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGQWQKYDVKESSPSKATAYINWAPEP
WSLRVQSTTSFDVSDAEGNDINGYTTVDFISSWQLPVGTLSFSVENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRG
RTFGLNYSVLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iutA NP_839219.1 ferric siderophore receptor Virulence SHI-2 Protein 0.0 100
iutA NP_709458.2 ferric siderophore receptor Virulence SHI-2 Protein 0.0 100
iutA AAK71635.1 IutA Virulence SHI-3 Protein 0.0 99
iutA AAD44750.1 IutA Virulence SHI-2 Protein 0.0 99
iutA YP_002414042.1 Ferric aerobactin receptor Virulence Not named Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iutA NP_839219.1 ferric siderophore receptor VFG0619 Protein 0.0 100
iutA NP_839219.1 ferric siderophore receptor VFG1085 Protein 0.0 99
iutA NP_839219.1 ferric siderophore receptor VFG0936 Protein 0.0 99