Gene Information

Name : argH (S3709)
Accession : NP_838924.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : argininosuccinate lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0165
EC number : 4.3.2.1
Position : 3600239 - 3601612 bp
Length : 1374 bp
Strand : -
Note : catalyzes the formation of arginine from (N-L-arginino)succinate

DNA sequence :
ATGGCACTTTGGGGCGGGCGTTTTACCCAGGCAGCAGATCAACGGTTCAAACAATTCAACGACTCACTGCGCTTTGATTA
CCGTCTGGCGGAGCAGGATATTGTTGGCTCTGTGGCCTGGTCCAAAGCCTTGGTAACGGTCGGCGTGTTAACCGCAGAAG
AGCAGGCGCAACTGGAAGAGGCGCTGAACGTGTTGCTGGAAGATGTTCGCGCCAGGCCACAACAAATCCTTGAAAGCGAC
GCCGAAGATATCCATAGCTGGGTGGAAGGCAAACTGATCGACAAAGTGGGCCAGTTAGGCAAAAAGCTGCATACCGGGCG
TAGCCGTAATGATCAGGTAGCGACTGACCTGAAACTGTGGTGCAAAGATACCGTTAGCGAGTTACTGACGGCTAACCGGC
AGCTGCAATCGGCGCTGGTGGAAACCGCACAAAACAATCAGGACGCGGTAATGCCAGGTTACACTCACCTGCAACGCGCC
CAGCCGGTGACGTTCGCGCACTGGTGCCTGGCCTATGTTGAGATGCTGGCGCGTGATGAAAGCCGTTTGCAGGATGCGCT
TAAGCGTCTGGATGTCAGCCCATTAGGCTGTGGCGCGCTGGCGGGAACGGCCTATGAAATCGACCGTGAACAGTTAGCAG
GCTGGCTGGGCTTTGCTTCGGCGACCCGTAACAGTCTGGACAGCGTTTCTGACCGTGACCATGTGTTGGAACTGCTTTCT
GCTGCCGCTATCGGCATGGTGCATCTGTCGCGTTTTGCTGAAGATCTGATTTTCTTTAACACCGGCGAAGCGGGGTTTGT
GGAGCTTTCGGACCGCGTGACTTCCGGTTCATCATTAATGCCGCAGAAGAAAAACCCGGATGCGCTGGAGCTGATTCGCG
GTAAATGCGGCCGGGTGCAGGGTGCGTTAACCGGCATGATGATGACGCTGAAAGGTTTGCCGCTGGCTTACAACAAAGAT
ATGCAGGAAGACAAAGAAGGTCTGTTCGACGCGCTCGATACCTGGCTGGACTGCCTGCATATGGCGGCGCTGGTACTGGA
CGGCATTCAGGTGAAACGTCCGCGTTGTCAGGAAGCGGCGCAGCAGGGGTATGCGAACGCCACTGAACTGGCGGATTACC
TGGTGGCGAAAGGCGTACCTTTCCGCGAGGCGCACCATATTGTGGGTGAAGCGGTGGTGGAAGCCATTCGTCAGGGCAAA
CCGCTGGAAGATCTGCCACTCAGTGAGTTGCAGAAATTCAGTCAGGTGATTGGCGAAGATGTCTATCCGATTCTGTCGCT
ACAATCGTGCCTCGAAAAGCGTGCGGCAAAAGGCGGCGTCTCACCGCAGCAGGTGGCGCAGGCGATTGCTTTTGCGCAGG
CTCGGTTAGAGTAA

Protein sequence :
MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESD
AEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLS
AAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKD
MQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGK
PLEDLPLSELQKFSQVIGEDVYPILSLQSCLEKRAAKGGVSPQQVAQAIAFAQARLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00324 YP_008207789.1 Argininosuccinate lyase Not tested AbaR25 Protein 3e-87 49
BJAB0868_00328 YP_008211654.1 Argininosuccinate lyase Not tested AbaR26 Protein 3e-87 49