Gene Information

Name : ribD (S0359)
Accession : NP_836080.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 362087 - 363190 bp
Length : 1104 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
GTGCAGGACGAGTATTACATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACCCACCCCAACCCGAATGT
CGGGTGCGTCATTGTCAAAGATGGCGAAATTGTCGGTGAAGGTTACCACCAACGAGCGGGTGAACCACATGCCGAAGTAC
ACGCGTTGCGTATGGCGGGTGAAAAAGCCAAAGGCGCAACGGCGTATGTGACACTCGAACCCTGTAGCCATCATGGCCGT
ACGCCACCGTGCTGTGACGCACTCATCGCCGCTGGCGTAGCGCGCGTGGTCGCAGCGATGCAAGATCCTAACCCGCAGGT
CGCTGGGCGTGGACTTTACCGTCTGCAACAGGCTGGCATTGACGTCAGCCACGGGCTGATGATGAGTGAAGCCGAGCAAT
TGAATAAAGGCTTTCTCAAGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGCCGC
ACGGCGATGGCGAGCGGCGAAAGCCAGTGGATCACTTCGCCTCAGGCGCGGCGCGACGTACAACGACAGCGCGCACAAAG
TCATGCCATTTTAACCAGCAGCGCCACGGTGCTGGCGGATGATCCAGCCTTAACAGTGCGTTGGTCTGAACTGGATGAAC
AAACTCAGGCGCTCTACCCGCAACAAAATCTCCGCCAGCCAGTACGTATTGTGATTGATAGCCAAAATCGCGTGACGCCG
GAACATCGCATTGTGCAGCAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTCGTGAGTGGCCGGAAACGGT
GCGTACCTTGCTGATTCCAGAGCATAAAGGTCATCTGGATCTGGTTGTACTGATGATGCAACTGGGTAAACAGCAGATTA
ACAGCATCTGGGTGGAAGCGGGGCCAACGCTCGCTGGCGTATTGCTACAGGCGGGTTTAGTCGATGAGCTGATTGTCTAT
ATCGCACCTAAACTATTAGGCAGCGACGCCCGTGGATTATGCTCGCTGCCAGGGCTTGAGAAATTAGCCGACGCCCCCCA
ATTTAAATTCAAAGAGATACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTGGGTGCATGA

Protein sequence :
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVAAMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRQRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPVRIVIDSQNRVTP
EHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGVLLQAGLVDELIVY
IAPKLLGSDARGLCSLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 1e-60 47
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 1e-60 47