Gene Information

Name : actP (S3594)
Accession : NP_838828.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 3466028 - 3467677 bp
Length : 1650 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGCCAGCCAACGAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCAT
CAAAACGCGTACGTTCTCGTAGCGACTACTACACCGCAGGCGGCAATATCACTGGCTTCCAGAACGGGCTGGCGATTGCC
GGGGACTATATGTCCGCCGCCTCATTCTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGGCTGATCTACTC
GTTGGGCTTCCTGGTGGGCTGGCCAATCATTCTGTTTCTGATTGCCGAACGTCTGCGTAACCTGGGACGCTACACCTCTG
CCGATGTGGCCTCTTATCGTCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTAGTGGTGGCGCTT
TACCTTATCGCTCAGATGGTAGGCGCAGGTAAACTGATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTGGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTACAAATTATCAAAGCTGTGC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAACAATCTGTTCAGCGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAACCGGGCGGACTGGTGAAAGATCCGATCTCCGCGCTCTCTCT
GGGGCTGGGACTGATGTTTGGTACGGCGGGCTTGCCGCACATTCTGATGCGCTTCTTTACAGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGATTTATGGGCTACTTCTATATTCTGACCTTTATTATCGGCTTCGGCGCGATC
ATGCTTGTTGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCGGCCGTTCACCT
GGCGAATGCAGTGGGCGGCAACCTATTCCTCGGTTTTATTTCAGCGGTTGCTTTCGCCACTATCCTCGCGGTGGTTGCGG
ATCTGACGCTGGCGGGCGCATCGGCGGTTTCGCATGACTTGTACGCTAACGTCTTCAAAAAAGGCGCGACCGAACGTGAA
GAGCTGCGGGTATCAAAAATCACCGTACTGATCCTCGGCGTGATTGCGATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTTATGGTAGGCCTTGCGTTTGCCATCGCGGCGAGCTGTAACTTCCCGATCATTCTGCTTTCCATGTACTGGT
CGAAACTGACTACCCGTGGCGCGATGCTGGGCGGCTGGCTGGGGCTGATTACCGCAGTGGTGCTGATGATCCTCGGCCCG
ACTATTTGGGTACAGATCCTCGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGCATCTGGTTCTTCTCGGCAACCGATAACTCAGCGGAAGGGGCGCGCGAGCGTGAACTGTTCCGCGCGCAGT
TTATCCGCTCCCAGACCGGCTTTGGCGTTGAGCAAGGCCGCGCACATTAA

Protein sequence :
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTSADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVADLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 3e-129 58
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 8e-73 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP NP_838828.1 acetate permease BAC0564 Protein 0.0 99
actP NP_838828.1 acetate permease BAC0570 Protein 3e-141 65