Gene Information

Name : phoB (S0344)
Accession : NP_836066.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : transcriptional regulator PhoB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 345784 - 346473 bp
Length : 690 bp
Strand : +
Note : two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB

DNA sequence : 
ATGGCGAGACGTATTCTGGTCGTAGAAGATGAAGCTCCAATTCGCGAAATGGTCTGCTTCGTGCTCGAACAAAATGGCTT
TCAGCCGGTCGAAGCGGAAGATTATGACAGTGCTGTGAATCAACTGAATGAACCCTGGCCGGATTTAATTCTCCTTGACT
GGATGTTACCTGGCGGCTCCGGTATCCAGTTCATCAAACACCTCAAGCGCGAGTCGATGACCCGGGATATTCCAGTGGTG
ATGTTGACCGCCAGAGGGGAAGAAGAAGATCGCGTGCGCGGCCTTGAAACCGGCGCGGATGACTATATCACCAAGCCATT
TTCGCCGAAGGAGCTGGTGGCGCGAATCAAAGCGGTAATGCGCCGTATTTCGCCAATGGCGGTGGAAGAGGTGATTAAGA
TGCAGGGATTAAGTCTCAACCCGACATCTCACCGAGTGATGGCGGGCGAAGAGCCGCTGGAGATGGGGCCGACAGAATTT
AAACTGCTGCACTTTTTTATGACGCATCCTGAGCGCGTGTACAGCCGCGAGCAGCTGTTAAACCACGTCTGGGGAACTAA
CGTGTATGTGGAAGACCGCACGGTCGATGTCCACATTCGTCGCCTGCGTAAAGCACTGGAGCCCGGCGGGCATGACCGCA
TGGTGCAGACCGTGCGCGGTACAGGATATCGTTTTTCAACCCGCTTTTAA

Protein sequence : 
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVV
MLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIKMQGLSLNPTSHRVMAGEEPLEMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 6e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB NP_836066.1 transcriptional regulator PhoB HE999704.1.gene2815. Protein 4e-40 44
phoB NP_836066.1 transcriptional regulator PhoB CP001918.1.gene5135. Protein 3e-24 43
phoB NP_836066.1 transcriptional regulator PhoB NC_002952.2859905.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_013450.8614421.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_007793.3914279.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_007622.3794472.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_002745.1124361.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_009782.5559369.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_002951.3237708.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_003923.1003749.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_002758.1121668.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB NC_009641.5332272.p0 Protein 1e-36 41
phoB NP_836066.1 transcriptional regulator PhoB CP000647.1.gene2531. Protein 5e-34 41
phoB NP_836066.1 transcriptional regulator PhoB CP001918.1.gene3444. Protein 2e-33 41