Gene Information

Name : yhcJ (S3476)
Accession : NP_838725.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : 5.1.3.9
Position : 3347525 - 3348214 bp
Length : 690 bp
Strand : -
Note : Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence : 
ATGTCGTTACTTGCACAACTGGATCAAAAAATCGCTGCTAACGGTGGCCTGATTGTCTCCTGCCAGCCGGTTCCTGACAG
CCCGCTCGATAAACCCGAAATCGTCGCAGCCATGGCATTAGCGGCAGAGCAGGCGGGCGCGGTTGCCATTCGCATCGAAG
GTGTGGCAAATCTGCAAGCCACGCGTGCGGTGGTGAGCGTGCCGATTATTGGAATTGTGAAACGCGATCTGGAGGATTCT
CCGGTACGCATCACGGCCTATATTGAAGATGTCGATGCGCTGGCGCAGGCGGGCGCGGACATTATCGCCATTGACGGCAC
CGACCGCCCGCGTCCGGTGCCTGTTGAAACGCTGCTGGCACGTATCCATCATCACGGTTTACTGGCGATGACCGACTGCT
CAACGCCGGAAGACGGCCTGGCATGCCAAAAGCTGGGAGCCGAAATTATTGGCACTACGCTTTCTGGCTATACCACGCCT
GAAACGCCAGAAGAGCCGGATCTGGCGCTGGTGAAAACGTTGAGCGAAGCCGGATGTCGGGTGATTGCCGAAGGGCGTTA
CAACACGCCTGCTCAGGCGGCAGATGCGATGCGCCACGGCGCGTGGGCGGTGACGGTCGGTTCTGCCATTACGCGTCTTG
AACACATTTGTCAGTGGTACAACACAGCGATGAAAAAGGCGGTGCTATGA

Protein sequence : 
MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDS
PVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
ETPEEPDLALVKTLSEAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 7e-38 59
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 6e-38 58
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 9e-38 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yhcJ NP_838725.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 2e-38 58