Gene Information

Name : ygiX (S3270)
Accession : NP_838546.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional regulator QseB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3151702 - 3152361 bp
Length : 660 bp
Strand : +
Note : response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes

DNA sequence : 
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGTGACGGCATCAAAACTGGCCTTAGTAAAATGGGTTTTAGTGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAGAAAGGTCAGCGTGAGCCGGTACTGAACCTGACCGCG
CGTGATGCGTTAGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAGGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Protein sequence : 
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLNLTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 9e-40 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0487 Protein 2e-39 44
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0638 Protein 2e-30 44
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0083 Protein 2e-36 43
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0347 Protein 2e-33 42
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB NC_002516.2.879194.p Protein 4e-30 41
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0308 Protein 5e-36 41
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0197 Protein 9e-36 41
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB BAC0111 Protein 7e-34 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB VFG0473 Protein 1e-39 46
ygiX NP_838546.1 DNA-binding transcriptional regulator QseB VFG1390 Protein 6e-32 42