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Name : sigA (S4824) Accession : NP_838462.1 Strain : Shigella flexneri 2457T Genome accession: NC_004741 Putative virulence/resistance : Virulence Product : serine protease Function : - COG functional category : S : Function unknown COG ID : COG4625 EC number : - Position : 3052614 - 3056471 bp Length : 3858 bp Strand : + Note : residues 1 to 1285 of 1285 are 100.00 pct identical to residues 1 to 1285 of 1285 from NRprotein_Feb03 : >ref|NP_708742.1| exported serine protease SigA [Shigella flexneri 2a str. 301] gb|AAF67320.1|AF200692_1 exported serine protease SigA [Shigella flexn DNA sequence : ATGAATAAAATTTATTCACTGAAATATAGTCATATTACAGGTGGATTAGTTGCTGTTTCTGAACTGACCCGGAAAGTTAG TGTCGGTACATCAAGAAAGAAAGTTATCCTCGGTATTATTTTATCCTCAATATATGGAAGTTATGGCGAAACAGCATTTG CAGCAATGCTGGATATAAATAATATATGGACCCGCGATTATCTTGACCTTGCTCAAAACAGAGGAGAGTTCAGACCGGGT GCAACAAATGTTCAATTAATGATGAAAGATGGAAAGATATTTCATTTTCCAGAACTACCTGTACCTGATTTTTCTGCTGT TTCCAACAAAGGTGCAACAACATCAATTGGAGGTGCGTACAGTGTTACTGCGACTCATAACGGTACACAGCATCATGCAA TAACAACACAGTCATGGGATCAGACAGCATATAAAGCAAGTAACAGAGTATCATCTGGCGACTTTTCGGTTCATCGTCTG AATAAATTCGTCGTGGAAACAACAGGGGTTACGGAGAGTGCCGACTTCTCACTTTCTCCCGAAGATGCGATGAAAAGATA TGGCGTAAACTACAACGGTAAGGAACAAATAATTGGCTTCAGAGCAGGTGCCGGAACAACCTCAACGATATTAAACGGCA AACAATATCTGTTTGGACAAAACTATAATCCCGACTTGTTAAGCGCAAGTCTTTTTAATCTGGACTGGAAAAACAAGAGT TACATTTATACCAACAGAACCCCTTTTAAAAACTCACCAATTTTTGGCGATAGTGGTTCTGGTTCTTATCTATATGATAA AGAACAACAAAAATGGGTTTTCCATGGTGTTACCAGTACAGTTGGTTTTATCAGTAGTACCAATATAGCCTGGACAAACT ACTCGTTATTTAATAATATTCTGGTAAACAATTTAAAAAAGAATTTCACAAACACTATGCAGCTGGATGGTAAAAAACAA GAGTTATCATCGATTATAAAAGATAAGGACCTGTCTGTCTCAGGAGGAGGGGTATTAACGCTCAAGCAGGATACCGATCT TGGCATTGGCGGGCTTATATTCGATAAGAACCAGACATATAAAGTGTACGGAAAAGATAAGTCTTATAAAGGTGCCGGGA TAGATATTGATAATAATACCACCGTTGAATGGAATGTTAAGGGCGTTGCCGGAGATAATCTGCATAAAATAGGTAGTGGT ACTCTGGATGTAAAAATAGCACAGGGAAATAACCTTAAAATAGGTAATGGGACTGTCATCCTTAGTGCTGAAAAAGCCTT CAATAAAATTTACATGGCCGGAGGTAAAGGTACGGTAAAAATAAATGCCAAAGACGCTTTAAGCGAAAGCGGTAATGGCG AAATCTATTTTACCAGAAATGGCGGAACACTGGATCTAAACGGCTATGACCAGTCATTTCAGAAAATCGCAGCAACAGAT GCGGGAACAACCGTAACGAACTCAAACGTGAAGCAATCAACATTATCACTTACTAATACTGATGCATATATGTACCATGG GAATGTATCAGGTAATATAAGCATAAATCATATTATCAATACTACCCAGCAACATAACAATAATGCCAATCTGATCTTTG ATGGCTCAGTCGATATCAAAAACGATATCTCTGTCCGGAATGCACAGTTAACATTACAAGGACATGCGACAGAACATGCC ATATTTAAAGAAGGCAATAACAACTGTCCAATTCCTTTTTTATGTCAAAAAGACTATTCTGCTGCCATAAAGGACCAGGA AAGCACTGTAAATAAACGTTACAATACGGAATATAAGTCCAACAATCAGATAGCCTCTTTTTCCCAGCCCGACTGGGAAA GTCGTAAATTTAATTTCCGGAAATTAAATTTAGAAAACGCAACCCTGAGTATAGGCCGGGATGCTAATGTAAAAGGACAC ATAGAGGCTAAAAACTCTCAAATTGTTCTGGGAAATAAAACTGCATACATTGACATGTTCTCAGGAAGAAACATTACTGG CGAAGGTTTTGGATTCAGACAACAGCTTCGCTCCGGGGATTCAGCAGGCGAAAGTAGTTTCAACGGCAGTCTGAGTGCTC AAAACAGCAAAATAACTGTTGGTGATAAATCAACTGTTACTATGACTGGTGCATTATCCTTAATTAATACAGACCTGATT ATCAACAAAGGAGCTACTGTTACCGCCCAGGGAAAAATGTATGTAGATAAAGCTATTGAACTGGCCGGAACCCTGACATT AACAGGCACCCCTACAGAAAATAATAAATACAGCCCGGCAATCTATATGTCAGATGGATATAATATGACAGAAGATGGTG CCACGTTAAAGGCTCAAAATTATGCCTGGGTCAATGGTAATATAAAATCAGACAAAAAAGCATCTATTCTGTTTGGTGTT GACCAGTATAAAGAAGATAACCTGGACAAAACCACACACACACCGCTGGCTACAGGTTTGCTGGGTGGCTTTGATACTTC TTATACCGGAGGTATTGATGCTCCTGCAGCCTCAGCCAGCATGTATAACACCTTATGGAGAGTAAACGGACAGTCAGCCC TGCAATCATTAAAAACCCGCGACAGTCTTTTGTTGTTTAGTAACATAGAGAATTCGGGTTTCCATACTGTGACAGTAAAC ACACTGGATGCCACTAATACTGCTGTGATTATGCGGGCTGATCTGAGCCAGTCTGTAAATCAATCGGATAAACTCATTGT TAAAAATCAGTTAACCGGAAGCAATAACAGTCTGTCGGTCGATATACAGAAAGTGGGAAATAATAACTCAGGATTAAACG TTGACCTGATAACAGCCCCAAAAGGAAGCAATAAAGAGATATTTAAAGCCAGTACTCAGGCCATAGGTTTCAGCAACATA TCTCCTGTGATCAGCACGAAAGAGGATCAGGAACATACCACGTGGACCCTGACCGGATATAAGGTGGCTGAAAATACAGC ATCTTCCGGTGCAGCAAAATCGTATATGTCCGGTAATTACAAAGCCTTCCTGACAGAAGTCAACAACCTGAATAAACGAA TGGGGGATCTGCGTGACACCAATGGCGAGGCCGGTGCATGGGCCCGCATCATGAGCGGAGCAGGTTCAGCTTCTGGTGGA TACAGTGACAACTACACCCATGTGCAGATTGGTGTGGATAAAAAACATGAGCTGGATGGACTTGACCTTTTCACTGGTCT GACTATGACGTATACCGACAGTCATGCCAGCAGTAATGCATTCAGTGGCAAGACGAAGTCCGTCGGGGCAGGTCTGTATG CTTCCGCTATATTTGACTCTGGTGCCTATATCGACCTGATTAGTAAGTATGTTCACCATGATAATGAGTACTCGGCGACC TTTGCTGGACTCGGAACAAAAGACTACAGTTCTCATTCCTTGTATGTGGGTGCTGAAGCAGGCTACCGCTATCATGTAAC AGAAGACTCCTGGATTGAGCCGCAGGCAGAACTGGTTTATGGGGCCGTATCAGGTAAACGGTTCGACTGGCAGGATCGCG GAATGAGCGTGACCATGAAGGATAAGGACTTTAATCCGCTGATTGGGCGTACCGGTGTTGATGTGGGTAAATCCTTCTCC GGTAAGGACTGGAAAGTCACAGCCCGCGCCGGCCTTGGCTACCAGTTTGACCTGTTTGCCAACGGTGAAACCGTACTGCG TGATGCGTCCGGTGAGAAACGTATCAAAGGTGAAAAAGACGGTCGTATTCTCATGAATGTTGGTCTCAACGCCGAAATTC GCGATAATCTTCGCTTCGGTCTTGAGTTTGAGAAATCGGCATTTGGTAAATACAACGTGGATAACGCGATCAACGCCAAC TTCCGTTACTCTTTCTGA Protein sequence : MNKIYSLKYSHITGGLVAVSELTRKVSVGTSRKKVILGIILSSIYGSYGETAFAAMLDINNIWTRDYLDLAQNRGEFRPG ATNVQLMMKDGKIFHFPELPVPDFSAVSNKGATTSIGGAYSVTATHNGTQHHAITTQSWDQTAYKASNRVSSGDFSVHRL NKFVVETTGVTESADFSLSPEDAMKRYGVNYNGKEQIIGFRAGAGTTSTILNGKQYLFGQNYNPDLLSASLFNLDWKNKS YIYTNRTPFKNSPIFGDSGSGSYLYDKEQQKWVFHGVTSTVGFISSTNIAWTNYSLFNNILVNNLKKNFTNTMQLDGKKQ ELSSIIKDKDLSVSGGGVLTLKQDTDLGIGGLIFDKNQTYKVYGKDKSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSG TLDVKIAQGNNLKIGNGTVILSAEKAFNKIYMAGGKGTVKINAKDALSESGNGEIYFTRNGGTLDLNGYDQSFQKIAATD AGTTVTNSNVKQSTLSLTNTDAYMYHGNVSGNISINHIINTTQQHNNNANLIFDGSVDIKNDISVRNAQLTLQGHATEHA IFKEGNNNCPIPFLCQKDYSAAIKDQESTVNKRYNTEYKSNNQIASFSQPDWESRKFNFRKLNLENATLSIGRDANVKGH IEAKNSQIVLGNKTAYIDMFSGRNITGEGFGFRQQLRSGDSAGESSFNGSLSAQNSKITVGDKSTVTMTGALSLINTDLI INKGATVTAQGKMYVDKAIELAGTLTLTGTPTENNKYSPAIYMSDGYNMTEDGATLKAQNYAWVNGNIKSDKKASILFGV DQYKEDNLDKTTHTPLATGLLGGFDTSYTGGIDAPAASASMYNTLWRVNGQSALQSLKTRDSLLLFSNIENSGFHTVTVN TLDATNTAVIMRADLSQSVNQSDKLIVKNQLTGSNNSLSVDIQKVGNNNSGLNVDLITAPKGSNKEIFKASTQAIGFSNI SPVISTKEDQEHTTWTLTGYKVAENTASSGAAKSYMSGNYKAFLTEVNNLNKRMGDLRDTNGEAGAWARIMSGAGSASGG YSDNYTHVQIGVDKKHELDGLDLFTGLTMTYTDSHASSNAFSGKTKSVGAGLYASAIFDSGAYIDLISKYVHHDNEYSAT FAGLGTKDYSSHSLYVGAEAGYRYHVTEDSWIEPQAELVYGAVSGKRFDWQDRGMSVTMKDKDFNPLIGRTGVDVGKSFS GKDWKVTARAGLGYQFDLFANGETVLRDASGEKRIKGEKDGRILMNVGLNAEIRDNLRFGLEFEKSAFGKYNVDNAINAN FRYSF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| sigA | NP_838462.1 | serine protease | Virulence | SHI-1 | Protein | 0.0 | 100 |
| sigA | NP_708742.1 | serine protease | Virulence | SHI-1 | Protein | 0.0 | 100 |
| sigA | AAF67320.1 | exported serine protease SigA | Virulence | SHI-1 | Protein | 0.0 | 100 |
| sat | YP_002414040.1 | Serine protease | Not tested | Not named | Protein | 0.0 | 55 |
| espC | AAG37043.1 | enterotoxin EspC | Virulence | espC PAI | Protein | 0.0 | 54 |
| pic | NP_838464.1 | serine protease precurser | Virulence | SHI-1 | Protein | 1e-172 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| sigA | NP_838462.1 | serine protease | VFG0630 | Protein | 0.0 | 100 |
| sigA | NP_838462.1 | serine protease | VFG0862 | Protein | 0.0 | 57 |
| sigA | NP_838462.1 | serine protease | VFG0844 | Protein | 0.0 | 56 |
| sigA | NP_838462.1 | serine protease | VFG0902 | Protein | 0.0 | 55 |
| sigA | NP_838462.1 | serine protease | VFG0772 | Protein | 0.0 | 54 |
