Gene Information

Name : S2859 (S2859)
Accession : NP_838190.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2749333 - 2750574 bp
Length : 1242 bp
Strand : +
Note : CP4-57 prophage; integrase

DNA sequence :
ATGGCAAGACAAACCAAACCTCTATCCGTTAAGGAAATCGAATCTGCTAAACCCAAGGAAGCGGACTACGTTCTCTATGA
TGGCGATGGCCTTGAGCTACTCATTAAATCCAGCGGGAGTAAAATCTGGCAGTTTCGCTACATTCGCCCTGTCACCAAGA
CACGAGCAAAGAAAAGCATAGGCCCTTACCCGTCAGTTACCCTTGCCGATGCCAGAAACTACCGTGCAGAGTCCCGCTCA
CTCCTAGCTAAACAGATTGATCCGCAGGAACATCAGCAAGAACAATTGCGTAGTTCGCTGGAAGCCAAAACCAATACTTT
CCAGCTCGTAGCTGAACGTTGGTGGAATGTGAAGAAAGCCAGTGTGACAGAGGACTATGCGGAAGATATCTGGCGCTCTC
TTGAAAGAGATGTCTTTCCTGCGATTGGCGACGTTAGCGTTACAGATATTAAAGCTCATACACTGGTTCAGGCCGTACAA
CCGGTTCAGGCCAGAGGAGCACTGGAAACGGTTCGTCGCCTGTGTCAACGTATTAATGAGGTCATGATCTATGCCCAGAA
CACAGGGCTGATTGATGCTGTTCCCAGCGTTAATATCGGTAAAGCCTTCGAAAAGCCTCAGAAAAAGAACATGCCCAGCA
TTCGACCGGATCAGCTATCTCAACTGATGCAGACAATGCGAACAGCCAGCATTAGCCTTTCCACACGCTGCCTGTTCATG
TGGCAACTTCTTACTATTACCCGCCCTGCCGAAGCGGCTGAAGCTCGCTGGGAAGAAGTAGACATAGAAGCGCAAGAGTG
GAAGATTCCCGCAGCACGCATGAAAATGAACCGCGACCATACTGTTCCATTGTCAGATGAAGCAATAGCTGTGCTGGAGA
TGATGAAACCGCTAAGCGGCAACCGAGAATTTATCTTTCCTAGCCGTATCAAGCCCAACCAGCCTATGAACAGTCAGACT
GTTAACGCCTCACTAAAACGCGCAGGTTTTGGTGGTGTGCTTGTTTCGCATGGTCTGAGATCAATTGCCAGTACGGCTCT
TAATGAACAAGGCTTTCCGCCTGATGCCATTGAGGCAGCATTGGCCCATGTGGATAAGAATGAGGTTCGTCGTGCTTATA
ACCGCAGCGATTACCTGGAACAGCGTCGCCCGATGATGCAATGGTGGGCAAATTTTGTGATGGCAGCGGATCGTGGAAGC
ATGATTGAAGGTGGGATAAAAGGAATGAAGCTAGTTGGGTGA

Protein sequence :
MARQTKPLSVKEIESAKPKEADYVLYDGDGLELLIKSSGSKIWQFRYIRPVTKTRAKKSIGPYPSVTLADARNYRAESRS
LLAKQIDPQEHQQEQLRSSLEAKTNTFQLVAERWWNVKKASVTEDYAEDIWRSLERDVFPAIGDVSVTDIKAHTLVQAVQ
PVQARGALETVRRLCQRINEVMIYAQNTGLIDAVPSVNIGKAFEKPQKKNMPSIRPDQLSQLMQTMRTASISLSTRCLFM
WQLLTITRPAEAAEARWEEVDIEAQEWKIPAARMKMNRDHTVPLSDEAIAVLEMMKPLSGNREFIFPSRIKPNQPMNSQT
VNASLKRAGFGGVLVSHGLRSIASTALNEQGFPPDAIEAALAHVDKNEVRRAYNRSDYLEQRRPMMQWWANFVMAADRGS
MIEGGIKGMKLVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int AAK20773.1 integrase Not tested VPI Protein 7e-101 52
int AAK20803.1 integrase Not tested VPI Protein 7e-101 52
unnamed AAA82714.1 integrase Not tested VPI Protein 7e-101 52
VC0847 NP_230494.1 phage family integrase Not tested VPI-1 Protein 9e-101 52
VC0395_A0372 YP_001216328.1 phage family integrase Not tested VPI-1 Protein 9e-101 52
VC0516 NP_230167.1 phage integrase Not tested VSP-2 Protein 2e-100 49
VPI2_0001 ACA01818.1 phage family integrase Not tested VPI-2 Protein 9e-81 45
VC1758 NP_231394.1 phage family integrase Not tested VPI-2 Protein 4e-80 45
VC0395_A1357 YP_001217300.1 phage family integrase Not tested VPI-2 Protein 4e-80 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S2859 NP_838190.1 integrase VFG1092 Protein 2e-80 45