Gene Information

Name : S2709 (S2709)
Accession : NP_838059.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : arsenical resistance protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG0431
EC number : -
Position : 2603369 - 2604136 bp
Length : 768 bp
Strand : +
Note : residues 13 to 250 of 255 are 66.39 pct identical to residues 5 to 243 of 244 from GenPept : >gb|AAK23485.1| (AE005825) arsenical resistance protein ArsH, [Caulobacter crescentus CB15]

DNA sequence :
ATGAGACTTCGCCATCTTTCCGACCCCGATTCTTTGCCCGCTTTGGACAAATCCTTTGCCATCGAGCGCCCGGCGCTCGG
GCTGGCACCCGACGCCCCGCCGGTGCGTATCCTGCTGCTGTATGGCTCGCTGCGCGCCCGCTCGTTCTCACGGCTGGCCG
TCGAGGAAGCGGCCCGGCTGCTGCAATTCTTTGGCGCAGAAACACGCATCTTCGACCCGTCCGATTTGCCGTTGCCCGAT
CAAGTGCAAAGCGACGATCACCCGGCCGTCAAGGAGCTGCGCGCCCTGTCCGAGTGGTCAGAGGGACAAGTCTGGTGCAG
CCCGGAACGCCACGGTCAGATTACCAGTGTCATGAAGGCGCAGATTGACCATCTGCCGCTTGAAATGGCCGGCATCCGGC
CGACCCAAGGCCGCACCCTGGCCGTGATGCAGGTATCCGGCGGCTCGCAGAGCTTCAACGCCGTGAACACCTTGCGTCTG
CTCGGCCGCTGGATGCGAATGTTCACCATTCCGAACCAGTCGAGTATCGCCAAAGCGTTCCAAGAGTTCGACGCGGCGGG
CCGCATGAAGCCCTCGCCGTACTACGACCGAATAGCCGATGTGATGGAAGAACTGGTGCGCTTCACGGCGCTGGTACGGC
CGCACCGTGAAGCACTGACAGACCGCTATTCCGAACGGAAAGCGGCCGGCCACGTCATCGACGAGGCCACCGATCTTTCA
TCCATCGCCATTGCTCCCCAGCCACTACCAGAAAGCGAAACATCATGA

Protein sequence :
MRLRHLSDPDSLPALDKSFAIERPALGLAPDAPPVRILLLYGSLRARSFSRLAVEEAARLLQFFGAETRIFDPSDLPLPD
QVQSDDHPAVKELRALSEWSEGQVWCSPERHGQITSVMKAQIDHLPLEMAGIRPTQGRTLAVMQVSGGSQSFNAVNTLRL
LGRWMRMFTIPNQSSIAKAFQEFDAAGRMKPSPYYDRIADVMEELVRFTALVRPHREALTDRYSERKAAGHVIDEATDLS
SIAIAPQPLPESETS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BCAM0236 YP_002232867.1 putative NADPH-dependent FMN reductase Not tested BcenGI11 Protein 1e-66 67
arsH YP_001007636.1 putative arsenic resistance protein Not tested YAPI Protein 1e-66 63
arsH CAJ77015.1 arsenic resistance protein Not tested AbaR1 Protein 1e-64 60
arsH ADZ05766.1 arsenic resistance protein Not tested AbaR11 Protein 1e-64 60
arsH AFC76432.1 ArsH Not tested AbaR5 Protein 1e-64 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S2709 NP_838059.1 arsenical resistance protein BAC0595 Protein 1e-61 69
S2709 NP_838059.1 arsenical resistance protein BAC0034 Protein 2e-63 58