Gene Information

Name : S0235 (S0235)
Accession : NP_835957.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : IS911 orfA
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 240794 - 241846 bp
Length : 1053 bp
Strand : -
Note : residues 72 to 350 of 350 are 99.64 pct identical to residues 1 to 279 of 279 from GenPept : >gb|AAL72449.1| (AF386526) InsB [Shigella flexneri 2a]

DNA sequence : 
ATGACAAGATGGGTCAAACAACTGCGTGATGAGCGTCAGGGCAAAACACCAAAAGCCTCCCCCATTACCCCGGAACAAAT
TGAAATCCGTGAGCTCAGGAAAAAGCTACAACGCATTGAAATGGAGAATGAAATATTAAAAAGGCTCCGCGCTCTTGATG
TCAGACTCCCTGAACAGTTCTCGATAATCGGGAAACTCAGAGCGCATTATCCTGTGGTCACACTCTGCCATGTGTTCGGG
GTTCATCGCAGCAGCTACAGATACTGGAAAAACCGTCCTGAAAAACCAGACGGCAGACGGGCTGTATTACGCAGTCAGGT
ACTTGAGCTACATGGCATCAGCCACGGTTCGGCCGGAGCAAGAAGCATCGCCACAATGGCAACCCGGAGAGGCTACCAGA
TGGGACGCTGGCTTGCTGGCAGGCTCATGAAAGAGCTGGGGCTGGTCAGCTGTCAGCAGCCGACTCACCGGTATAAACGT
GGTGGTCATGAACATGTTGCTATCCCTAACTACCTTGAAAGGCAGTTCGCCGTGACCGAGCCAAATCAGGTGTGGTGCGG
TGATGTGACCTATATCTGGACGGGTAAGCGCTGGGCGTACCTCGCCGTTGTTCTCGACCTGTTCGCAAGAAAACCAGTGG
GCTGGGCCATGTCGTTCTCGCCGGACAGCAGGCTCACCATGAAAGCGCTGGAAATGGCATGGGAAACCCGTGGTAAGCCC
GGCGGGGTGATGTTCCACAGCGATCAGGGCAGTCATTATACGAGCAGGCAGTTCCGGCAGTTATTGTGGCGATACCAGAT
CAGACAGAGTATGAGCCGGCGCGGAAACTGCTGGGATAACAGCCCAATGGAACGCTTCTTCAGGAGTCTGAAGAACGAAT
GGATGCCGGTGGTGGGTTACGTAAGCTTCAGCGAGGCAGCTCACGCCATAACGGACTATATCGTTGGATATTACAGTGCA
CTAAGACCGCACGAATATAACGGTGGGTTACCCCCAAACGAATCGGAAAATCGATACTGGAAAAACTCTAACTCGGTGGC
CAGTTTTTGTTGA

Protein sequence : 
MTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMENEILKRLRALDVRLPEQFSIIGKLRAHYPVVTLCHVFG
VHRSSYRYWKNRPEKPDGRRAVLRSQVLELHGISHGSAGARSIATMATRRGYQMGRWLAGRLMKELGLVSCQQPTHRYKR
GGHEHVAIPNYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTMKALEMAWETRGKP
GGVMFHSDQGSHYTSRQFRQLLWRYQIRQSMSRRGNCWDNSPMERFFRSLKNEWMPVVGYVSFSEAAHAITDYIVGYYSA
LRPHEYNGGLPPNESENRYWKNSNSVASFC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orfB YP_001217329.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-96 66
orfB ACX47958.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-96 66
VPI2_0008c ACA01825.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-96 66
orfB AGK06910.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-96 66
overlap with orfA characteristic of IS3 family members AGK06947.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-96 66
orfB AGK06993.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-96 66
orfB AGK07051.1 IS1359 transposase; OrfB Not tested SGI1 Protein 2e-96 66
VC1789 NP_231424.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-96 66
RS04 AAP82949.1 putative transposase Not tested PAPI-2 Protein 3e-63 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S0235 NP_835957.1 IS911 orfA VFG1122 Protein 1e-96 66