Gene Information

Name : S2278 (S2278)
Accession : NP_837702.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : IS1 orfB
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG1662
EC number : -
Position : 2160671 - 2161174 bp
Length : 504 bp
Strand : -
Note : residues 1 to 167 of 167 are 89.82 pct identical to residues 1 to 167 of 167 from GenPept : >gb|AAK18365.1|AF348706_54 (AF348706) IS1 transposase [Shigella flexneri]

DNA sequence :
ATGTCGCGCCAGTGCACGCATTATGGGCGTTGGCCTCAACACGGTTTTACGTCACTTAAAAAACTCAGGCCGCAGTCGGT
AACCTCGCGCATACAACCGGGCAGTGATGTGATTGTCTGCGCTGAAATGGACGAACATTGGGGCTACGTCGGTGCTAAAT
CACGTCAGCGCTGGCTGTTTTACGCGTATGACAGGATACGGAGGACGGTTGTGGCGCACGTCTTCGGTGAACGCACTCTG
GCCACACTGGAGCGTCTTCTGAGCCTGCTGTCGGCCTTTGAGGTCGTGGTATGGATGACGGATGGCTGTCCGCTGTATGA
ATCACGCCTGAAGGGAAAGCTGCACGTTATCAGCAAGCGTTACACTCAGCGCATTGAGCGACATAATCTGAATCTGAGAC
AACATCTGGCAAGGCTGGGACGGAAGTCACTGTCGTTCTCAAAATCGGTGGAGCTGCATGACAAGGTCATCGGGCATTAT
CTGAACATAAAACACTATCAGTAA

Protein sequence :
MSRQCTHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMDEHWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTL
ATLERLLSLLSAFEVVVWMTDGCPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHY
LNIKHYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Z1632 NP_287135.1 IS1 protein InsB Not tested TAI Protein 7e-66 99
tnpH AAD44742.1 TnpH Not tested SHI-2 Protein 1e-65 99
S4059 NP_839227.1 IS1 orfB Not tested SHI-2 Protein 1e-65 99
Z1192 NP_286727.1 IS1 protein InsB Not tested TAI Protein 7e-66 99
aec38 AAW51721.1 InsB Not tested AGI-3 Protein 1e-50 99
insB NP_709463.1 IS1 ORF2 Not tested SHI-2 Protein 3e-47 98
insB NP_709451.1 IS1 ORF2 Not tested SHI-2 Protein 2e-65 98
insB ADD91744.1 transposase Not tested PAI-I AL862 Protein 9e-62 93
EC042_4085 YP_006098368.1 transposase Not tested Tn2411 Protein 1e-61 89
EC042_4113 YP_006098397.1 transposase Not tested Tn2411 Protein 1e-61 89
insB NP_458736.1 insertion element IS1 protein InsB Not tested SPI-7 Protein 1e-61 89
InsB (Tn1) CAJ77072.1 Transposase Not tested AbaR1 Protein 3e-59 88

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S2278 NP_837702.1 IS1 orfB VFG0612 Protein 6e-66 98