Gene Information

Name : S2243 (S2243)
Accession : NP_837678.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : IS1 orfB
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG1662
EC number : -
Position : 2117764 - 2118267 bp
Length : 504 bp
Strand : +
Note : residues 1 to 167 of 167 are 90.41 pct identical to residues 1 to 167 of 167 from GenPept : >gb|AAD44742.1|AF141323_13 (AF141323) TnpH [Shigella flexneri]

DNA sequence :
ATGTCGCGCCAGTGCACGCATTATGGGCGTTGGCCTCAACACGGTTTTACGTCACTTAAAAAACTCAGGCCGCAGTCGGT
AACCTCGCGCATACAACCGGGCAGTGATGTGATTGTCTGCGCTGAAATGGACGAACATTGGGGCTACGTCGGTGCTAAAT
CACGTCAGCGCTGGCTGTTTTACGCGTATGACAGGATACGGAGGACGGTTGTGGCGCACGTCTTCGGGGAACGCACTCTG
GCCACACTGGAGCGTCTTCTGAGCCTGCTGTCGGCCTTTGAGGTCGTGGTATGGATGACGGATGGCTGGCCGCTGTATGA
ATCACGCCTGAAGGGAAAGCTGCACGTTATCAGCAAGCGTTACACTCAGCGCATTGAGCGACATAATCTGAATCTGAGAC
AACATCTGGCAAGGCTGGTACGGAAGTCACTGTCGTTCTCAAAATCGGTGGAGCTGCATGACAAGGTCATCGGGCATTAT
CTGAACATAAAACACTATCAGTAA

Protein sequence :
MSRQCTHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMDEHWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTL
ATLERLLSLLSAFEVVVWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLVRKSLSFSKSVELHDKVIGHY
LNIKHYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tnpH AAD44742.1 TnpH Not tested SHI-2 Protein 4e-68 100
S4059 NP_839227.1 IS1 orfB Not tested SHI-2 Protein 5e-68 100
insB NP_709463.1 IS1 ORF2 Not tested SHI-2 Protein 1e-49 99
Z1192 NP_286727.1 IS1 protein InsB Not tested TAI Protein 4e-67 99
Z1632 NP_287135.1 IS1 protein InsB Not tested TAI Protein 4e-67 99
insB NP_709451.1 IS1 ORF2 Not tested SHI-2 Protein 9e-68 99
aec38 AAW51721.1 InsB Not tested AGI-3 Protein 2e-52 99
insB ADD91744.1 transposase Not tested PAI-I AL862 Protein 7e-63 93
EC042_4085 YP_006098368.1 transposase Not tested Tn2411 Protein 1e-62 89
EC042_4113 YP_006098397.1 transposase Not tested Tn2411 Protein 1e-62 89
insB NP_458736.1 insertion element IS1 protein InsB Not tested SPI-7 Protein 1e-62 89
InsB (Tn1) CAJ77072.1 Transposase Not tested AbaR1 Protein 4e-60 88

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S2243 NP_837678.1 IS1 orfB VFG0612 Protein 3e-68 99